The Project Scientist will focus their research on neuro-oncology and identifying unexplored anticancer strategies. Additionally, the Project Scientist will provide statistical analysis and abstract and manuscript preparation. The Project Scientist will also have the opportunity to submit research grants independently as well as perform research projects in collaboration with faculty in the division of Regenerative Medicine. The Project scientist will occasionally teach and provide lectures to graduate students.

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Under full supervision, the Clinical Trials Regulatory Research Associate is responsible for the development and maintenance of regulatory documents pertaining to the clinical trials conducted by investigators at the Cancer Center. Key to this role is the preparation of clinical trial protocols and related regulatory documents for submission to the UCSD Human Research Protections Program (UCSD's Institutional Review Board or IRB) in order to obtain its approval for the clinical trials to proceed. The Regulatory Research Associate will act as a resource to investigators and staff for interpretation and execution of complex clinical research regulations, policies & procedures concerning the conduct of clinical trials, including those of the FDA, HHS, UCSD IRB, and the CTO. This position requires regular interaction with a variety of internal and external contacts including Cancer Center investigators and staff, UCSD IRB staff, study sponsors and/or their representatives. Other duties assigned as needed.

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Under supervision, perform cell culture and propagation of tumor cell lines as well as transfection and cellular fractionation experiments. Perform computational analysis of complex genomic, epigenomic, and transcriptional data from public and lab generated data to infer biologic changes. Provide assistance to laboratory members in computational analysis of experiments. Create code to interpret experiments and biologic pathway analysis. Independently maintain tumor cell and neurosphere cultures for use in transfection and cellular fractionation experiments. Responsible for maintaining and inventory of frozen cell stocks and routine testing for mycoplasma contamination. Process tumor specimens by extracting DNA and RNA, as well as perform cloning and subcloning of DNA fragments. Perform molecular biology/cell biologic assays, to study mouse models of cancer. Perform ordering, inventory, and basic laboratory supply management. Act as the Area Safety Coordinator for assigned laboratory space. Responsible for EH&S compliance of the laboratory and the required training of lab personnel. Prepare chemical, biological, and radiation protocols for submission to EH&S committees for review. Assist Principal Investigator with departmental budgetary and personnel matters. Integrate information obtained from scientific journals for use in the laboratory and disseminate this information to other lab members. Other duties assigned as needed.

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Perform tumor immunology studies consisting of murine models of cancer, animal breeding and genotyping, flow cytometry, single cell sequencing, immunohistochemistry, in vitro cell biology, and in vitro biochemistry. Murine tumor biology studies will include xenograft, orthotopic and spontaneous tumor growth and metastasis assays, immunological analysis, treatment of animals with experimental therapeutic agents by gavage, intravenous and intraperitoneal methods, breeding and genotyping of transgenic and mutant mice, and immune cell isolations. Perform major surgery, including small animal anesthesia. In addition, perform immunohistochemistry of frozen and fixed tissues or cells. Conduct various in vitro cell biology techniques to include performing flow cytometry analysis of cell surface protein expression, cell adhesion and migration assays, transfecting cells with expression constructs, preparing lysates of cells in culture or tissues, quantification, ELISA assays, SDS PAGE, Western and Immunoblotting and gel electrophoresis. Additionally, perform recombinant DNA techniques to include preparing plasmids and maintaining plasmid stocks, analyzing DNA and RNA purification, and conducting DNA electrophoresis, and RT-PCR. Make innovative contributions regarding experimental design and methodology, using published scientific data in referred journals, as well as online using search engines and subject-specific websites, to make recommended changes to current protocols and practices. Troubleshoot problems for quality control on immunochemical and histochemical procedures. Maintain and prepare accurate records of all experiments. Assist in the preparation of data for publication. Assume responsibility for lab maintenance and safety training. Provide training and work direction in areas of expertise as needed. Maintain and prepare accurate records of all experiments. Assist in the preparation of data for publication. Other duties assigned as needed.

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Directly enhance the academic and research missions of the department of Radiation Medicine and Applied Sciences as well as Moores Cancer Center through research in the area of health services research which will help put the department in a position to compete for larger training grants, center grants, or project grants through the NCI. Will directly support the mission of Moores Cancer Center, specifically the Cancer Control Program (CCP) and the NCI-funded P30 Cancer Center Support Grant through research interests in health services research including the field of financial toxicity surrounding cancer care. Additionally, the incumbent will support the goals of the SDSU/UCSD Cancer Partnership (supported by an NCI U54 grant), which focuses on research, education, and community outreach to reduce the impact of health disparities in San Diego. We expect the incumbent will collaborate with other faculty members within the department on research projects. Will direct a research program that supports the overarching goal of the "Excellence Search for Diverse Faculty in Health Sciences" program which is to build a more diverse faculty and aims to foster a diverse and inclusive community of scholars to enhance our academic and research missions.

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Under close supervision of the Assistant Director, Clinical Trials Finance Support, the incumbent will support invoicing and reconciliation of clinical trials to optimize revenue collections for the MCC CTO’s portfolio. Provides assistance in maintaining 50-100 financial accounts for studies and reviews financial documentation across multiple systems (including, but not limited to: agreements and budgets, payment remittances, grant awards, coverage analysis, etc.). Utilizes multiple systems to document and manage Accounts Receivable (A/R) in CTMS, Financial System of Record, and other systems as needed. Develop good working relationships with Sponsors and CROs in efforts to maintain collection procedures and processes to help resolve issues of overdue accounts. Assist with reviewing reports for Disease Teams and communicating A/R improvements to Disease Team and individual study staff (e.g., CRCs, Data Coordinators, etc.) to resolve any delinquency status. Assist with addressing and correcting billing issues, and follow-up actions required to ensure the timely receipt of payments.

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The Clinical Informatics Specialist is responsible for triaging, designing, managing, and meeting analytics needs across UCSD Health Cancer Services. Responsible for producing reports in Reporting workbench, Radar, Clarity, Crystal and Tableau. This involves the development and implementation of the organization's information systems and tools that are applied to clinical information. Works closely with UC San Diego Health’s IS Analytics Department, and other stakeholders across all hospital/healthcare departments to optimize effective use of systems. Coordinates analytical support for Cancer Center clinical operations and quality initiatives, including business analytics/performance metrics. Defines systems and applications to support various functions. May provide customer service, troubleshooting and maintenance. Applies skills and experience as a seasoned clinical informatics professional to projects of medium size at all levels of complexity, or portions of large projects.

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The Administrative Specialist position is part of the Moores Cancer Center at UC San Diego Health, one of only 40 National Cancer Institute-designated Comprehensive Cancer Centers in the United States. This designation is reserved for cancer centers with the highest achievements in cancer research, clinical care, education, and community contributions. Moores Cancer Center strives to stay at the forefront of emerging cancer research in a patient centric environment. Reporting directly to the Executive Business Administrator of the Moores Cancer Center Director’s Office, the Administrative Specialist serves as a non-clinical resource to support the administrative business operations for oncology and radiation therapy services directors, senior leaders, and other functional area department teams. The Specialist administers the day-to-day business operations for defined operational programs and activities in the areas of finances, facilities, payroll, space planning, student services, human resources, communications, employee morale activities, event planning, comprehensive database and website management, informational technology and safety.

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Reporting to the Network Sites Project Manager, the Network Coordinator II is responsible for coordinating and monitoring clinical trials including providing all aspects of protocol oversight, including but not limited to screening for patient eligibility, data collection and analysis, ensuring protocol compliance, adverse drug/therapy reaction reports, monitoring patient treatment and toxicities, laboratory and specimen collection, processing, and submission, and maintenance of accurate and complete clinical research files.

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The Clinical Research Coordinator (CRC) II will coordinate and oversee start-up procedures, implementation, recruitment, screening, enrollment, and maintenance of subjects. Create informational and recruitment materials and act as a liaison with other UCSD departments and agencies for the purpose of implementation of studies. The Clinical Research Coordinator (CRC) II will plan, develop and implement start-up procedures for multiple phase I-III research studies in assigned disease team as well as lead, direct, and coordinator operational efforts. Assure compliance with state and federal regulatory guidelines. Oversee the quality of the medical and clinical research data. Provide direction and guidance to investigators. Provide education and information to the general public concerning the ongoing clinical trials. Assist PIs with proposals, progress reports and manuscripts. Independently create original documents and policies for assigned disease teams. Work closely with federal and state regulatory officials.

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Reporting directly to the Disease Team Project Manager, the Clinical Research Coordinator I is responsible for coordinating and managing clinical trials including providing all aspects of protocol management, including screening for patient eligibility, data collection and analysis, ensuring protocol compliance, adverse drug reaction reports, monitoring patient treatment and toxicities, laboratory and specimen submission, and maintenance of accurate and complete clinical research files. Assist the regulatory department with Human subjects submissions, renewals, and safety reports. Directly communicate with assigned physicians and disease groups, including attending weekly meetings and tumor boards. Provide direct assistance to the Project Manager in reviewing and verifying university research account statements, professional fee statements, and invoicing. Other duties assigned as needed.

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Reporting directly to the Disease Team Project Manager, the Clinical Research Coordinator I is responsible for coordinating and managing clinical trials including providing all aspects of protocol management, including screening for patient eligibility, data collection and analysis, ensuring protocol compliance, adverse drug reaction reports, monitoring patient treatment and toxicities, laboratory and specimen submission, and maintenance of accurate and complete clinical research files. Assist the regulatory department with Human subjects submissions, renewals, and safety reports. Directly communicate with assigned physicians and disease groups, including attending weekly meetings and tumor boards. Provide direct assistance to the Project Manager in reviewing and verifying university research account statements, professional fee statements, and invoicing. Other duties assigned as needed.

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Under general supervision, the Assistant Clinical Research Coordinator (ACRC) will work in the Pancreatic Cancer Center in collaboration with the group's clinical and research teams to execute clinical studies including the Pancreatic Cancer Early Detection (PRECEDE) consortium study and other studies relevant to pancreatic cancer, pancreatic cysts, and early detection as needed. The ACRC will be responsible for various aspects of protocol management such as assisting with initiation, implementation, and management of clinical studies, recruiting and consenting participants, collecting and entering research data, updating study and patient records, submitting protocol applications and amendments to local IRB, sample acquisition and downstream processing, and maintenance of accurate and complete research files. Other duties assigned as needed.

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The Simeone lab, with 25 years of continuous NIH funding, has been driven to understand the molecular determinants that drive pancreatic cancer development and progression. The lab works to define therapeutic vulnerabilities and uses laboratory-based models to study approaches for early detection, prevention, and development of novel therapeutics for pancreatic cancer. Specific areas of research interest are the DNA damage response and therapeutic vulnerabilities, understanding the complexities of the tumor microenvironment and mechanisms that drive therapeutic resistance, and developing new therapeutics to more effectively target pancreatic cancer.

Under general direction of the Principal Investigator, the Lab Manager will have dual responsibilities of overseeing and helping to drive the scientific direction and research productivity of the lab. The Lab Manager will serve as a senior scientist making significant innovative contributions pertaining to the development and design of new projects, grant writing, and establishing research collaborations between the Simeone lab and others across the UCSD community and beyond. For the right applicant, this position has the potential to lead to independent funding in the future.

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Under supervision, assist with the characterization of "POLQ Synthetic Lethality in HR-Deficient Pancreatic Adenocarcinoma" and preclinical studies. Assist with recombinant DNA work and genome engineering. Assist with various cell culture techniques such as performing flow cytometry analysis of cell surface protein expression, cell propagation, contaminant testing, and cryopreservation. Assist with mouse colony management and genotyping using established PCR techniques. Work with small animals and assist with procedures such as surgery, pancreatic orthotopic injections, ultrasound imaging, and monitoring pregnancies. Assist with immunohistochemistry of frozen and fixed tissues or cells. Assist with protein biochemistry techniques including protein quantification, SDS PAGE, immunoprecipitation, and Western blotting. Maintain and prepare accurate records of all experiments. Assist in the preparation of data for publication. Other duties assigned as needed.

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Under supervision, assist with preparation and execution of experiments using biological and chemical materials. Tasks will include preparation of standardized media and reagents; upkeep of laboratory apparatus and facilities; ordering and organization of laboratory supplies; record-keeping and organization of experimental outputs onthe laboratory computer notebook and databases. The assistant will have an opportunity to observe and assist senior laboratory members with experiments involving cell culture, PCR, specimen sectioning, molecular cloning, and gel electrophoresis. Perform all other duties as assigned.

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The Nurse Supervisor provides support and care to the clients and maintains professional standards of care, following the ANA Code of Ethics. Under the general supervision of the Nurse Manager, the Nurse Supervisor is responsible for immediate supervision of a wide variety of clinic and infusion functions at the Hillcrest campus, planning and performing direct and indirect nursing interventions, and is responsible for supervising, organizing, planning, assessing and monitoring the medical services provided by UC San Diego Health.

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Using the nursing process in the planning and delivery of care, the Registered Nurse (RN) complies with all regulations and standards of regulatory and accrediting bodies and maintains a safe level of knowledge and skills with technical procedures. The Radiation Oncology RN will be responsible for completing regular biopsychosocial assessments and care plans with patients, communicating and collaborating with healthcare teams to ensure coordination of care, providing education to patients/families regarding treatment plans, medications, advance directives, appointments and so forth, assessing patients and families for additional resource and referral needs, evaluating response to plan of care and ensuring appropriate documentation.

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The Oncology Nursing Float Pool Clinic RNs will work within all domains of outpatient cancer services (clinics, BMT, Radiation Oncology) to provide competent, confident patient care excellence in coverage of FMLAs or leaves greater than 2 weeks. These positions require dynamic, experienced oncology RNs with previous oncology and/or infusion experience, exceptional verbal and written communication skills with team members, patients, and families in the application of top of license care, including but not limited to: assessment, care coordination planning, intervention, evaluation and patient/family education.

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The Oncology Nursing Float Pool Infusion RNs will work all infusion center locations to provide competent, confident patient care excellence in coverage of FMLAs or leaves greater than 2 weeks. These positions require dynamic, experienced oncology RNs with previous oncology and/or infusion experience, exceptional verbal and written communication skills with team members, patients, and families in the application of top of license care, including but not limited to: assessment, symptom intervention, evaluation and patient/family education during the safe delivery of cancer and non-cancer related IV therapies.

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The Multi-Specialty Clinic brings together specialists in medical oncology, surgical oncology, hematology-oncology, and gynecologic oncology. We are looking for dynamic oncology clinic RNs with strong critical thinking, communication, care coordination, and patient advocacy skills. This position will cross-train and work with multiple oncology disease teams as needed to ensure patient safety and continuity of care. Additional opportunities include Unit-Based Council membership, with the opportunity to identify, develop and implement performance improvement initiatives to improve patient care and staff wellbeing.

Autonomous nursing care is the ability of a nurse to assess and provide nursing actions as appropriate for patient care populations based on competence, professional expertise, and knowledge. The nurse is expected to practice autonomously consistent with ANA Standards of Practice and Professional Performance. Independent judgment is expected to be exercised within the context of interdisciplinary and multidisciplinary approaches to patient care.

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This position will work with the outpatient Palliative Care team to provide palliative services to patients and families throughout UCSD. The Palliative Care RN, in collaboration with the Palliative Care team, focuses on assessment, diagnosis and treatment of human responses to actual or potentially life-limiting illness and necessitates a dynamic, caring relationship with the patient and family to reduce suffering. This position requires a strong clinical knowledge of symptom management, including pain, and experience in working with multi-disciplinary teams to optimize care for the patient. Strong clinical, communication and advocacy skills are essential.The New Graduate Nurse Transition to Practice Program is accredited with distinction as a Practice Transition Program by the American Nurses Credentialing Center’s Commission on Accreditation in Practice Transition Programs. This program is multi-faceted and designed to support our New Grads with a comprehensive transition-to-practice experience through enhanced clinical learning, patient simulation activities, hands-on skill training and so much more!

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Under the general supervision of a registered nurse in the assigned clinic, the Sr. LVN performs a wide variety of patient care activities in support of clinic activity. Duties include prioritizing and assisting in patient triage processing, preparation and assistance with patient examinations, administering medications, drawing blood, collecting and preparing laboratory tests, and patient education. The position requires initiative, able to prioritize critical demands, and the ability to work in a team environment.

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Under the general supervision of a registered nurse in the assigned clinic, the Sr. LVN performs a wide variety of patient care activities in support of clinic activity. Duties include prioritizing and assisting in patient triage processing, preparation and assistance with patient examinations, administering medications, drawing blood, collecting and preparing laboratory tests, and patient education. The position requires initiative, able to prioritize critical demands, and the ability to work in a team environment.

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Under the direct supervision of the Palliative Care Program Manager, and working alongside an inter-professional team, performs a wide variety of patient care activities in support of clinic activity. The Palliative Care Nurse case managers assist the medical provider in a case management role by prepping patients for their in-person/telemedicine visits, conducting pain, nausea, constipation, and sleep assessments, triage processing, preparation and assistance with patient examinations, and patient education. Will be responsible for managing a transition of care clinic, including scheduling patients for post discharge visits. Position requires initiative, able to prioritize, and multitasking.

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The Pharmacist Supervisor will provide direct supervision to pharmacists and technical support staff for the Moores/KOP infusion Pharmacy. The position will be a working position within the pharmacy and will report to the Moores/KOP Infusion Pharmacy Manager. The position will resolve problems, interpret policies (e.g. fiscal management, HR, contracts, resource management), supervise drug procurement, dispensing and counseling patients regarding their drug treatments. The Supervisor will oversee the operations of the pharmacy ensuring adherence to productivity and quality standards, internal policy requirements and external regulations. The position will participate in the implementation of quality and patient service improvement activities and suggest ways to improve professional and technical staff utilization and efficiency. The Supervisor will help onboard new staff. The Supervisor will advise and coach staff to identify resolutions for patient issues.

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Under general supervision, positions in this title can be assigned to Inpatient, Outpatient and Home Infusion units within the Pharmacy Department. The Pharmacy Technician, assists the pharmacist in the preparation of medications for patient use (oral and parenteral) according to established procedures; assists in the distribution of medications; performs computer order entry, record keeping, and billing functions; maintains inventory levels; Will perform assigned operational duties in a scheduled area and will assist pharmacists in completing medication orders and related distribution duties in the assigned areas.

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Radiation Therapy Technologists typically confer with Radiation Oncologists and work closely with Dosimetrists to discuss the treatment plan and the type of simulator films that will be necessary; place reference markings on the patients' body; review treatment procedures with the patient to reinforce the therapist's comments on reactions to therapy, to ensure that communication and emergency procedures are understood, and to advise on appropriate dietary and skin care procedures; position patients for single portal, multiple portal, rotation or cross beam therapy, providing immobilization devices as required; set up equipment according to the treatment plan verifying the placement of bars, wedges and similar devices; closely monitor the patient for unexpected reactions and report these deviations to the Therapist; and record delivered dosage values on the chart, verifying these values against the prescribed treatment plan.

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Seeking a dynamic leader who will play a crucial role in leading and overseeing patient navigation services within Cancer Services. This Manager will ensure a culturally competent patient navigation program through training, workflow enhancement, and ongoing program refinement. They will monitor program effectiveness and outcomes, collecting and analyzing data to make informed decisions and drive continuous improvement and appropriate workflow standardization. Building upon the success of the existing program, the Manager will partner with Cancer Services leaders to identify opportunities for programmatic expansion in alignment with clinical services geographic growth. The incumbent will cultivate positive relationships with physician leaders, providers, care team members and all UC San Diego Health staff to support patients throughout their cancer journey. In addition, they will establish and maintain relationships with philanthropic donors, community organizations and resources to provide patients with access to critical supportive services, financial assistance, and other resources.

The position supervises a team of non-clinical patient navigators, providing guidance, support, and mentorship to ensure the team delivers exceptional service to patients and caregivers obtaining oncology care. They provide oversight for patient navigators initiating contact with patients and families, ensuring proactive communication at each phase of treatment. The Manager will also directly provide patient navigation services.

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Under general supervision of the Administrative Director, the Mental Health Therapist provides all aspects of psychosocial mental and behavioral health services for oncology patients through the continuum of care: diagnosis, living with cancer, recurrence, end-of-life, and survivorship. Employs a model of patient care that focuses on providing patients/caregivers with supportive counseling, support groups, psychosocial assessments, therapeutic interventions, education, and community resource support information. Demonstrates compassion, warmth, and understanding of the psychosocial needs of oncology patients. Participates in multi-disciplinary treatment team.

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Under the general supervision of Cancer Services leadership, and in addition to performing the full range of operational level duties, the Clinical Social Worker II is responsible for administering social work services, including comprehensive psychosocial assessment and psychosocial support surrounding crisis intervention, adjustment to illness, psychoeducation and anticipatory guidance related to treatment, mental health, substance use, mandated reporting, transportation, lodging, financial/grant support, barriers to care/compliance, and linkage to additional resources as needed.

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Bone and Marrow Transplantation (BMT) is a highly complex and resource-intensive treatment requiring a specialized multi-disciplinary team. Under the general supervision of BMT leadership, the BMT Clinical Social Worker III provides clinical social work services, including comprehensive bio-psychosocial assessment and treatment planning; ongoing psychosocial evaluation; counseling for adjustment to illness and the impact of treatment; psycho-education; and linkage with resources, e.g., support and financial assistance. Services are provided to patients and their caregivers in both out-patient and in-patient settings. The Clinical Social Worker III also participates in related department functions. Performs all other duties as assigned.

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Under the supervision of the Administrative Supervisor and Patient Access Lead and working in an independent manner, the Patient Access Per Diem will assist in ensuring patients are efficiently scheduled in the department. The Patient Access Per Diem will support multiple physicians. Assist with continuity and coordination of care by scheduling all patient appointments from consultation to follow-up. Using sound judgment, will independently set priorities, meet established deadlines and work effectively in a high volume environment. Will provide support to all Patient Services functions as needed. Adaptability will be necessary, as the individual will help fill in and complete tasks based on staffing. Main duties will be patient access related; scheduling patients for consults, simulations, or follow up appointments. Obtaining outside records and superb communication with patients.

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Reporting directly to the Director of Clinical Operations, Patient Access and Supportive Care, the Patient Navigation Program Supervisor is responsible for the management and supervision of patient navigation program staff in facilitating the delivery of an excellent experience for patients and caregivers obtaining oncology care. The incumbent will ensure the development and maintenance of positive program relationships with physician leaders, providers, care team members and all UC San Diego Health staff to facilitate and support patients throughout their cancer journey. The Patient Navigation Program Supervisor will oversee navigator responsibilities, evaluations, schedules, coverage, onboarding, training, recruitment and retention. The supervisor will provide oversight for patient navigators initiating contact with patients and families and establishing ongoing, proactive communication at each new phase of treatment.

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