APPLY FOR A FARA RESEARCH GRANT

General Research Grant Deadlines and Budget Limits

Grant TypeLetter of Intent (LOI) DeadlineApplication DeadlineAward NoticeGrant Start DatesMaximum Budget (USD)

General Research Grant

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

$125,000 per year for 1 or 2 years

Award for Innovative Mindset (AIM)

No LOI

Apr 1

Jul 1

Aug 1 – Sep 1

$100,000 for 1 year

Keith Michael Andrus Cardiac Award

Feb 15

Apr 15

Aug 1

Sep 1 – Oct 1

$125,000 per year for 1 or 2 years

Kyle Bryant Translational Research Award

Feb 15

Apr 15

Aug 1

Sep 1 – Oct 1

$200,000 per year for 1 or 2 years

Bronya J. Keats Research Collaboration Award

Feb 15

Apr 15

Aug 1

Sep 1 – Oct 1

$175,000 per year for 1 or 2 years

Postdoctoral Research Award

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

$100,000 per year for 1 or 2 years

Postdoctoral Fellowship

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

Trainee salary up to 2 years

Graduate Research Fellowship

Mar 15

May 15

Sep 1

Oct 1 – Nov 1

$50,000 per year up to 3 years

Request for Proposals and Ad-hoc Requests

TBC

General Research Grant

The General Research Grant is open to qualified investigators proposing projects that align with FARA Research Priorities.

Maximum Budget (USD): $125,000 per year for 1 or 2 years

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

General Research Grants

FUNDED GRANT | Jan 2025

Rescuing frataxin expression by alternative splicing reprogramming with base editing

General Research Grant, Gene & Stem Cell Therapy Alessandro Quattrone, PhD,
University of Trento
FUNDED GRANT | Dec 2024

Application of RSwitch technology to improve Friedreich's ataxia viral gene therapy safety and efficacy: control of FXN transgene expression through a small molecule regulation

General Research Grant, Gene & Stem Cell Therapy Samuel Hasson, PhD,
Rgenta Therapeutics, Inc

Award for Innovative Mindset (AIM)

The Award for Innovative Mindset (AIM) supports the initial exploration of innovative, high-risk, high-gain, and potentially ground-breaking concepts in FA research, that will foster new directions, bring new perspectives to the field and address neglected issues in FA research. The presentation of preliminary and/or published data is encouraged, but not required.

Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design.

Research that is an incremental advance upon published data is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of FA.

Maximum Budget (USD): $100,000 for 1 year

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: N/A
  • Application Deadline: Apr 1
  • Award Notice: Jul 1
  • Grant Start Dates: Aug 1 – Sep 1
FUNDED GRANTS

Award for Innovative Mindset (AIM)

FUNDED GRANT | Dec 2024

Development of Epigenetic Editors for Frataxin Reactivation

Award for Innovative Mindset (AIM), Gene & Stem Cell Therapy Daniel Hart, PhD,
Epicrispr Biotechnologies, Inc.
FUNDED GRANT | Sep 2024

Deliverable in vitro transcribed mRNAs of Frataxin as a therapeutic approach for Friedreich ataxia

Award for Innovative Mindset (AIM), Gene & Stem Cell Therapy Lefkothea Papadopoulou, PhD,
Aristotle University of Thessaloniki
Named Grant Awards

Keith Michael Andrus Cardiac Award, Kyle Bryant Translational Research Award and Bronya J. Keats Research Collaboration Award

LOIs for the Keith Michael Andrus Cardiac Award (KMA), Kyle Bryant Translational Research Award (KB) and Bronya J. Keats Research Collaboration Award (BJK) are accepted by Feb 15 each year. These applications are competitive with general grant applications received within the same cycle and submission as a general grant type does not exclude an application from being considered for a named award. FARA will award up to one KMA, one KB and one BJK award per year, selected among applications that fit the criteria described below. When applying for these awards, a detailed budget justification must be provided. If funded, the amount approved by FARA may be different from the requested budget. This change could be as a result of the LOI reviews and/or the full application reviews, or it may be a decision made by FARA when the award is approved. 

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct

Keith Michael Andrus Cardiac Award

Kyle Bryant Translational Research Award

Bronya J. Keats Research Collaboration Award

Keith Michael Andrus Cardiac Award

The Keith Michael Andrus Cardiac Research Award was made in honor of its namesake to remember Keith’s legacy and to help advance our understanding and treatment of cardiomyopathy associated with FA. Proposals for this award should focus on advancing understanding and/or treatment of the cardiac involvement in FA.

Maximum Budget (USD): $125,000 per year for 1 or 2 years

FUNDED GRANTS

Keith Michael Andrus Cardiac Award

FUNDED GRANT | Sep 2024

Evaluating the cardioprotective effect of omaveloxolone on Friedreich ataxia heart disease

Keith Michael Andrus Cardiac Award, Cardiac Research Shiang Lim, MPharm, PhD,
St Vincent's Institute of Medical Research
FUNDED GRANT | Dec 2022

Advancing novel mitochondrial therapies for FA cardiomyopathy: a pragmatic collaboration to move new therapies forward

Keith Michael Andrus Cardiac Award, Cardiac Research Laura Kropp, PhD, MPH,
Stealth BioTherapeutics

Kyle Bryant Translational Research Award

The Kyle Bryant Translational Research Award honors its namesake for his diligent efforts to aid the rapid translation of basic research discoveries into clinical applications. Eligible applications should focus on accelerating completion of translational stage activities necessary for advancement to clinical study of a therapeutic candidate or development of novel tools that address a critical bottleneck to the discovery or development of therapies.

The specific aims must target one or more of the following:

  • Pre-clinical development and testing of potential therapeutics, biologics, and devices in cells and animals, when proof of concept has already been established 
  • Development of tools and technologies that can be used for therapy development, delivery of therapeutics or to address critical bottlenecks to drug development in FA
  • Identification of pharmacodynamic, monitoring and diagnostic biomarkers and novel clinical endpoints for clinical trials in FA, that will facilitate clinical development, elucidate disease variability, severity, and prognosis or optimize selection of patients for clinical trials
  • Clinical studies of patient outcome measures 

Maximum Budget (USD): $200,000 per year for 1 or 2 years

FUNDED GRANTS

Kyle Bryant Translational Research Award

FUNDED GRANT | Sep 2024

Developing the novel investigational mitochondrial therapeutic SBT-589 for Friedreich’s ataxia

Kyle Bryant Translational Research Award, Lead Candidates Laura Kropp, PhD, MPH,
Stealth BioTherapeutics
FUNDED GRANT | Aug 2022

Detection and enhancement of tissue NAD+ levels in Friedreich’s Ataxia

Kyle Bryant Translational Research Award, Outcome Measures & Biomarkers Joseph Baur, PhD & Shana McCormack, MD,
University of Pennsylvania and Children's Hospital of Philadelphia

Bronya J. Keats Research Collaboration Award

The Bronya J. Keats Research Collaboration Award honors its namesake for her academic career in understanding the GAA triplet repeat mutation in FA, and her continued role in managing FARA’s grant program. Proposals should focus on FA research that relies on collaboration among investigators from at least two different institutions. Special consideration will be given to proposals that involve international collaborations and bring new scientists to the FA community. The rationale for the collaboration needs to be convincing: it must clearly demonstrate that the research goals could not be achieved by just one of the participating groups and the synergy among the groups is essential for the success of the project.

Maximum Budget (USD): $175,000 per year for 1 or 2 years

FUNDED GRANTS

Bronya J. Keats Research Collaboration Award

FUNDED GRANT | Nov 2024

Impact of cerebellar transcranial direct current stimulation on FA brain and cerebellar neurophysiological fingerprints and on clinical symptoms assessed by multimodal evaluations

Bronya J. Keats Research Collaboration Award, Improving Clinical Outcomes Gilles Naeije, MD, PhD,
Université Libre de Bruxelles, Belgium
FUNDED GRANT | May 2020

Identification of genetic modifiers of Friedreich's ataxia

Bronya J. Keats Research Collaboration Award, Mechanism or Pathway of Disease Henry Houlden, MD, PhD,
University College London, UK

Postdoctoral Research Award

FARA offers a Postdoctoral Research Award as a mechanism to expand and retain young investigators in the FA biomedical research space.

For this application type, the Postdoctoral trainee is the PI of the grant proposal. Applicants must have completed at least 18 months of postdoctoral training. Eligible applicants are postdoctoral trainees with fewer than 7 years working as a postdoctoral trainee, accounting for career disruptions. Postdoctoral trainees should focus their research proposal on projects that fall within FARA Research Priorities. Applicants are required to submit a personal statement describing their current position and plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the junior investigator and mentor(s), as well as letters of support from all mentors are also required.

The only allowable budget items are the trainee’s salary/stipend, plus applicable fringe benefits, supplies and travel to conferences if adequately justified and directly related to the proposed research. The trainee is required to contribute at least 75% effort to the proposed work. The maximum direct salary that can be requested cannot exceed the NIH stipend level for 100% effort. If the trainee is contributing less than 100% effort then the stipend request must be reduced to correspond to this effort.  For example, if the trainee’s effort is 85%, then the stipend requested can be no more than 85% of the appropriate NIH stipend level.

Competitive candidates demonstrate qualities that will enhance FARA’s overall enterprise of understanding fundamentals of disease pathology and developing treatments and a cure for FA.

Maximum Budget (USD): $100,000 per year for 1 or 2 years

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

Postdoctoral Research Award

FUNDED GRANT | Mar 2025

Unraveling Epigenetic Mechanisms and Therapeutic Strategies for FXN Silencing in Friedreich’s Ataxia

Postdoctoral Research Award, Mechanism or Pathway of Disease Xiaonan Guan, PhD ,
New York Genome Center
FUNDED GRANT | Oct 2024

Enhancing Gene Therapy Delivery to the Brain via Human Blood-Brain Barrier Receptors

Postdoctoral Research Award, Gene & Stem Cell Therapy Changfan Lin, PhD,
California Institute of Technology

Postdoctoral Fellowship

FARA offers a Postdoctoral Fellowship to support young investigators in the FA biomedical research space. For this application type, the PI of the grant proposal may be either the trainee or the trainee's faculty advisor; however, both the trainee and advisor must be named in the application.

Eligible applicants are postdoctoral trainees with fewer than 6 years working as a postdoctoral trainee, accounting for career disruptions, and fewer than 4 years working in an FA lab as a postdoctoral trainee. Applicants are required to submit a personal statement describing their current position and plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the junior investigator and mentor(s), as well as letters of support from all mentors are also required. The only allowable budget item is the trainee salary/stipend (plus applicable fringe benefits), which must not exceed the appropriate NIH stipend level. Postdoctoral trainees should provide a minimum 75% effort contributed to the design, writing and implementation of the proposed work. The maximum direct salary that can be requested cannot exceed the NIH stipend level for 100% effort. If the trainee is contributing less than 100% effort then the stipend request must be reduced to correspond to this effort.  For example, if the trainee’s effort is 85%, then the stipend requested can be no more than 85% of the appropriate NIH stipend level. 

Maximum Budget (USD): Trainee salary for up to two years, plus applicable fringe benefits

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

Postdoctoral Fellowship

FUNDED GRANT | Nov 2024

Design and synthesis of SynGR library to probe into the role of NSD-2,3 proteins in FXN expression in FRDA

Postdoctoral Fellowship, Mechanism or Pathway of Disease Anushree Achari, PhD,
St. Jude Children’s Research Hospital
FUNDED GRANT | Oct 2024

Understanding the Pathogenesis of Friedreich’s Ataxia by Single-Cell Integration of Gene Expression, Epigenetics and Connectivity in the Cerebellar Nuclei

Postdoctoral Fellowship, Mechanism or Pathway of Disease Julian Cheron, MD, PhD,
Johns Hopkins University

Graduate Research Fellowship

The Graduate Research Fellowship provides 1 to 3 years of support for individuals engaged in graduate study leading to a Doctor of Philosophy (Ph.D.) degree (or equivalent).

FARA will award up to 3 Graduate Research Fellowships per year. For this application type, the PI/applicant of the grant proposal is the graduate student. Applicants need to be matriculated in the chosen graduate school and have a chosen thesis adviser at the time of application. Proof of passing qualifying exam, if applicable, is required at time of application or must be provided within a year of receiving the award, to receive funding for years 2 and 3. If passing a qualifying exam is not an institutional requirement, then the applicant must have been doing research in the adviser’s lab for at least the 6 months prior to the application deadline and must provide: (1) Institutional proof of acceptance to the PhD program; and (2) a letter from the adviser stating that the student will be supported by the adviser until completion of the student’s PhD degree (or equivalent). The research proposal must focus on projects that fall within FARA’s Research Priorities. Preliminary data are encouraged but not required. Applicants are required to submit a personal statement describing their plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the graduate student and the primary research mentor, as well as a mentor’s letter of support are also required. The only allowable budget items are the graduate student’s salary/stipend plus applicable fringe benefits (including health insurance) and tuition costs and fees that are not already covered by the institution. The majority of the student’s time should be dedicated to this project. Recipients of this Fellowship are encouraged to attend the International Congress for Ataxia Research, and FARA will facilitate their participation.

Eligibility

  • Individuals must be enrolled full-time in a research-based (dissertation-required) program, leading to a Ph.D. (or equivalent) at a not-for-profit U.S. or foreign institution of higher education at the time of application. Applicants must be matriculated in the chosen graduate school and have a chosen thesis adviser.
  • Proof of passing qualifying exam, if applicable, is required at the time of application or must be provided within a year of receiving the award to receive funding for years 2 and 3.
  • If passing a qualifying exam is not an institutional requirement, then the applicant must have been doing research in the adviser’s lab for at least the 6 months prior to the application deadline.
  • Individuals must be enrolled full-time and may not accept full-time teaching or research assistantships or internships during fellowship tenure.
  • May not be a recipient of another fellowship / studentship / scholarship, or a previous recipient of this fellowship.
  • Must remain in good academic standing per guidelines of the chosen graduate program.
  • This fellowship can support the Ph.D. portion of an M.D./Ph.D. joint program, if this is not already supported through institutional funds.

Maximum Budget (USD): $50,000 per year, up to 3 years

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: March 15
  • Application Deadline: May 15
  • Award Notice: September 1
  • Grant Start Dates: Oct. 1 – Nov. 1
FUNDED GRANTS

Graduate Research Fellowship

FUNDED GRANT | Sep 2024

Shortening GAA repeats in Friedreich's Ataxia

Graduate Research Fellowship, Gene & Stem Cell Therapy David Berryman ,
University of Florida
FUNDED GRANT | Sep 2024

NRF2 and MAO-Ai therapy to improve cardiac health and prevent arrhythmias in Friedreich’s ataxia

Graduate Research Fellowship, Lead Candidates Francisco Figueroa,
University of California, Davis

Request for Proposals and Ad-hoc Requests

All RFPs will be announced through this webpage and through our e-bulletin list. If you are not a subscriber please click below to sign-up. Lastly, FARA is willing to consider ad-hoc proposals off cycle that are high-value projects. For more information, please contact FARA at grants@curefa.org