Geoffrey Oxnard, MD, discusses the latest research in targeted therapies and molecular testing to treat lung cancer.
This presentation was originally given as part of "Living with Lung Cancer: A Forum for Patients and Caregivers" on Nov. 14, 2015 at Dana-Farber Cancer Institute in Boston, Mass.
These three articles from the Dana-Farber Cancer Institute blog discuss support for cancer caregivers, including a support group that provides companionship for caregivers, tips for maintaining a romantic relationship while caregiving, and guidance for coping with grief after the loss of a loved one to cancer.
Radiation therapy can be used to cure or palliate lung cancer depending on the cancer type and stage. For non-small cell lung cancer, conventional radiation therapy is used with surgery and chemotherapy for locally advanced stages, while stereotactic body radiation therapy is used for early stage cancers. For small cell lung cancer, conventional radiation therapy is used for limited stage disease. Palliative radiation therapy provides symptom relief for metastatic lung cancers.
This document discusses various breast imaging modalities for screening and diagnosis of breast cancer. It provides an overview of mammography, digital breast tomosynthesis, ultrasound, MRI, and molecular breast imaging. Mammography remains the primary screening tool, though its sensitivity decreases with breast density. Digital breast tomosynthesis has been shown to improve cancer detection rates compared to digital mammography alone. Ultrasound is useful as an adjunct but has high false positive rates for screening. MRI is recommended for screening high risk patients due to its high sensitivity. Molecular breast imaging is a potential adjunct screening tool for dense breasts that may help increase cancer detection over mammography alone.
Radiation therapy uses X-rays from a linear accelerator to precisely target tumors while sparing healthy tissue. Multiple low doses are given over several weeks to damage cancer cells' DNA. Daily X-rays and weekly CT scans ensure accurate positioning. Common side effects include skin reddening and swallowing pain, but risks of long-term effects are low. The goal is cure, though some treatments provide symptom relief.
1) The document discusses the roles and responsibilities of nurses according to various nursing theorists from Nightingale to Benner. It also discusses ethics, principles, and guidelines for nursing documentation.
2) Nursing theories discussed include Nightingale's environmental manipulation theory, Peplau's interpersonal processes theory, Henderson's 14 basic needs theory, and Orlando's nursing as interacting to meet needs theory.
3) The document provides an overview of nursing ethics, principles of documentation, and guidelines for accurate and thorough documentation.
This document summarizes evidence on the role of surgery for metastatic breast cancer (MBC). It finds that palliative surgery effectively controls symptoms for MBC patients. Prospective studies also suggest surgery may improve survival for responsive MBC patients with a limited number of metastases, especially those with ER+ disease. However, randomized trials yield mixed results on survival benefits. While definitive local therapy may be justified for select asymptomatic MBC patients, systemic therapy and targeted therapies remain the top priority for these patients overall.
Patients with ER+ breast cancer have many treatment options, and a better understanding of mechanisms of resistance to therapy is leading to new treatments.
This document discusses the treatment of pain and neuropathy in metastatic breast cancer patients. It outlines the goals of pain management, different types of cancer pain and their causes, the WHO pain ladder for treatment approaches, opioid and non-opioid pain medication options and their side effects, managing neuropathy, and the importance of a multidisciplinary team approach to pain control and palliative care.
How can cancer patients manage the symptoms of chemobrain? Learn more about this side effect of cancer treatment, which can sometimes cause decreased short-term memory, problems finding words, short attention span, and difficulty concentrating and multitasking.
Exercise is recommended for cancer patients to improve health and recovery. Start with low-impact activities like walking, yoga, or stretching, and slowly increase intensity over time. Track exercise progress and set specific, measurable, and time-bound fitness goals. Reduce sitting and seek help from fitness experts or workout partners.
Commonly thought of as a childhood cancer, leukemia is actually much more common in adults. While symptoms of the disease are consistent among each, researchers are beginning to understand more about underlying biological factors that influence the different ways leukemia develops in children and adults. What are other differences and similarities?
Clinical trials are testing new HER2-targeted therapies for metastatic HER2-positive breast cancer. Some highlights of ongoing trials include a trial of Trastuzumab Deruxtecan for patients resistant to T-DM1, a trial adding hormonal therapy Fulvestrant to Neratinib, and a trial combining immunotherapy with chemotherapy and Trastuzumab. Participating in clinical trials helps advance treatment options and many trials provide access to promising new agents. Talking to your oncologist can help identify potential trials and determine if participation may be an option.
Overview of clinical trials for metastatic triple-negative breast cancer by Sara M. Tolaney, MD, MPH, Associate Director and Associate Director of Clinical Research at Susan F. Smith Center for Women's Cancers at Dana-Farber Cancer Institute.
Research increasingly shows that “energy balance” is important in breast cancer. Learn why exercise, weight, and diet are important for breast cancer patients.
Prostate cancer is a disease in which cancer forms in the tissues of the prostate, a male gland just below the bladder and in front of the rectum. Prostate cancer is rare in men younger than 50 years of age, and the chance of developing prostate cancer increases as men get older. In the United States, a man has a one in five chance of being diagnosed with prostate cancer in his lifetime.
There are many different pediatric brain tumor types and classifications based upon the tumor’s cell structure, composition, rate of growth, location, and other characteristics. A child’s tumor may have the same microscopic appearance to an adult tumor, but the mutations that cause its growth are completely different.
Radiation therapy uses X-rays from a linear accelerator to precisely target tumors while sparing healthy tissue. Multiple low doses are given over several weeks to damage cancer cells' DNA. Daily X-rays and weekly CT scans ensure accurate positioning. Common side effects include skin reddening and swallowing pain, but risks of long-term effects are low. The goal is cure, though some treatments provide symptom relief.
1) The document discusses the roles and responsibilities of nurses according to various nursing theorists from Nightingale to Benner. It also discusses ethics, principles, and guidelines for nursing documentation.
2) Nursing theories discussed include Nightingale's environmental manipulation theory, Peplau's interpersonal processes theory, Henderson's 14 basic needs theory, and Orlando's nursing as interacting to meet needs theory.
3) The document provides an overview of nursing ethics, principles of documentation, and guidelines for accurate and thorough documentation.
This document summarizes evidence on the role of surgery for metastatic breast cancer (MBC). It finds that palliative surgery effectively controls symptoms for MBC patients. Prospective studies also suggest surgery may improve survival for responsive MBC patients with a limited number of metastases, especially those with ER+ disease. However, randomized trials yield mixed results on survival benefits. While definitive local therapy may be justified for select asymptomatic MBC patients, systemic therapy and targeted therapies remain the top priority for these patients overall.
Patients with ER+ breast cancer have many treatment options, and a better understanding of mechanisms of resistance to therapy is leading to new treatments.
This document discusses the treatment of pain and neuropathy in metastatic breast cancer patients. It outlines the goals of pain management, different types of cancer pain and their causes, the WHO pain ladder for treatment approaches, opioid and non-opioid pain medication options and their side effects, managing neuropathy, and the importance of a multidisciplinary team approach to pain control and palliative care.
How can cancer patients manage the symptoms of chemobrain? Learn more about this side effect of cancer treatment, which can sometimes cause decreased short-term memory, problems finding words, short attention span, and difficulty concentrating and multitasking.
Exercise is recommended for cancer patients to improve health and recovery. Start with low-impact activities like walking, yoga, or stretching, and slowly increase intensity over time. Track exercise progress and set specific, measurable, and time-bound fitness goals. Reduce sitting and seek help from fitness experts or workout partners.
Commonly thought of as a childhood cancer, leukemia is actually much more common in adults. While symptoms of the disease are consistent among each, researchers are beginning to understand more about underlying biological factors that influence the different ways leukemia develops in children and adults. What are other differences and similarities?
Clinical trials are testing new HER2-targeted therapies for metastatic HER2-positive breast cancer. Some highlights of ongoing trials include a trial of Trastuzumab Deruxtecan for patients resistant to T-DM1, a trial adding hormonal therapy Fulvestrant to Neratinib, and a trial combining immunotherapy with chemotherapy and Trastuzumab. Participating in clinical trials helps advance treatment options and many trials provide access to promising new agents. Talking to your oncologist can help identify potential trials and determine if participation may be an option.
Overview of clinical trials for metastatic triple-negative breast cancer by Sara M. Tolaney, MD, MPH, Associate Director and Associate Director of Clinical Research at Susan F. Smith Center for Women's Cancers at Dana-Farber Cancer Institute.
Research increasingly shows that “energy balance” is important in breast cancer. Learn why exercise, weight, and diet are important for breast cancer patients.
Prostate cancer is a disease in which cancer forms in the tissues of the prostate, a male gland just below the bladder and in front of the rectum. Prostate cancer is rare in men younger than 50 years of age, and the chance of developing prostate cancer increases as men get older. In the United States, a man has a one in five chance of being diagnosed with prostate cancer in his lifetime.
There are many different pediatric brain tumor types and classifications based upon the tumor’s cell structure, composition, rate of growth, location, and other characteristics. A child’s tumor may have the same microscopic appearance to an adult tumor, but the mutations that cause its growth are completely different.
Soft tissue sarcoma refers to cancer that begins in the muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body. View the slideshow to learn more about signs and symptoms of this cancer, as well as risk factors.
Cancer-related fatigue is one of the most common problems patients face. Patients often report feeling wiped out during cancer treatments like chemotherapy and radiation, and for many, feeling tired or worn out continues into life after cancer treatment.
Here are 10 tips for alleviating treatment-related fatigue, through methods such as energy preservation and exercise – the latter of which is now known to be an effective strategy for combating this prevalent side effect.
This document summarizes a presentation on surgery for inflammatory breast cancer. It discusses that initial evaluation involves biopsy and determining if the disease is resectable. For resectable disease, the standard treatment is neoadjuvant chemotherapy followed by modified radical mastectomy and radiation therapy. The role of surgery is supported by studies showing improved survival with surgery. Immediate breast reconstruction is not recommended for IBC patients due to concerns about residual disease in the skin. However, delayed reconstruction after chemotherapy and surgery is an option, with tissue expanders and flaps being used in over 30 patients with low complication rates. Future areas of research include the role of local therapy for stage 4 disease and mapping lymphatic drainage.
This document summarizes radiation therapy for inflammatory breast cancer. It discusses the unique features of IBC that help define radiation fields, the use of tri-modality therapy including systemic therapy, surgery, and radiation. It describes the process of radiation therapy including CT simulation, immobilization, fields used to treat the chest wall and nodes, and techniques like bolus and dynamic multi-leaf collimator. Both short term and long term side effects of radiation are outlined, and future directions exploring concurrent therapies to improve effectiveness are presented.
1) Primary systemic therapy with chemotherapy is used to begin treatment for inflammatory breast cancer (IBC) since it is inoperable at diagnosis.
2) IBC has been shown to be relatively chemoresistant, so identifying targeted therapeutic approaches is important.
3) Clinical trials specifically designed for IBC are needed, as including IBC patients in locally advanced breast cancer trials makes it difficult to interpret outcomes for IBC. Such trials should incorporate translational components to further understand IBC biology.
There are more than 120 different types of brain tumors that may occur in adults. Learn about the five most common types.
For more on brain tumors, visit www.dana-farber.org/braintumor
Multiple myeloma is a type of cancer that begins in plasma cells, white blood cells that produce antibodies. It is also called Kahler's disease, myelomatosis or plasma cell myeloma.
Integrative therapies range from individual treatments, such as acupuncture, massage, and Reiki, to group programs for movement, meditation, and creative arts, as well as exercise and nutritional consultations.
Research conducted by Dana-Farber investigators and others has shown that, when used in conjunction with traditional cancer care, integrative therapies can help ease cancer-related symptoms and improve your quality of life.
The air ambulance service offered by Panchmukhi Air and Train Ambulance Services in Patna and Delhi is a risk-free medical transportation medium that helps transfer patients without any delay. We provide an air ambulance with life-saving facilities that guarantee the stability of the patient's health until the journey is completed.
More@ https://shorturl.at/RBYs3
Web@ https://shorturl.at/bwbF7
Starting a home health care business can be a rewarding venture, providing essential services to those in need while building a profitable enterprise. This guide outlines the key steps to help you establish a successful home health care business. More Visit: https://www.homehealthbiz.com/consulting-services/
Leif Rogers - A Leading Plastic SurgeonLeif Rogers
Leif Rogers, M.D., F.A.C.S., is a leading plastic surgeon in Beverly Hills and Pasadena, known for his expertise in microvascular breast reconstruction, facial aesthetics, and body contouring. A Columbia University graduate, he completed specialized reconstructive training at the University of Pittsburgh and a cosmetic fellowship in Manhattan. An active researcher, he contributes to studies on wound healing and tissue engineering. He volunteers with HELPs International, bringing medical aid to underserved communities in Mexico and Guatemala.
THE POWER - TOP 10 HOPSPITAL BRANDS IN VIETNAM 2025, Google GeminiIgnite Capital
Top 10 Hospital Brands in Vietnam
Vietnam’s healthcare sector has grown rapidly in recent years, offering a mix of public and private hospitals that deliver top-tier medical care. From advanced treatments and cutting-edge technology to highly trained specialists, these hospitals have earned their reputation as leaders in the field. Below are the top 10 hospital brands in Vietnam, recognized for their exceptional services and global healthcare standards.
Vinmec International Hospital
Part of the Vingroup conglomerate, Vinmec operates hospitals in major cities like Hanoi and Ho Chi Minh City. Its Times City and Central Park hospitals are JCI-accredited, reflecting a commitment to global healthcare standards.
Franco-Vietnamese Hospital (FV Hospital)
Located in Ho Chi Minh City, FV Hospital is Vietnam’s first JCI-accredited private hospital, offering specialized care across over 30 medical fields. Known for its high-end services, FV caters to both local and international patients.
Hoan My Medical Corporation
Since its establishment in 1997, Hoan My has become Vietnam’s largest private healthcare network, with 14 hospitals and seven clinics nationwide. The brand is known for offering affordable, quality healthcare across a wide range of specialties.
Cho Ray Hospital
As the largest public hospital in Ho Chi Minh City, Cho Ray offers a comprehensive array of medical services and advanced treatments. It serves both local residents and international patients, providing specialized care in various medical fields.
Hanoi Medical University Hospital
A prominent teaching hospital in Hanoi, this institution plays a critical role in medical education and research. It provides extensive services, contributing to the development of healthcare in Vietnam.
Family Medical Practice
With locations in Hanoi, Ho Chi Minh City, and Da Nang, Family Medical Practice caters mainly to expatriates. It emphasizes personalized care, high standards, and international-level healthcare services.
Columbia Asia International Hospital
Part of an international healthcare chain, Columbia Asia’s Ho Chi Minh City facility is known for its modern infrastructure, offering specialized care and meeting global medical standards.
City International Hospital
Located in Ho Chi Minh City, City International Hospital boasts state-of-the-art medical technology and offers a broad spectrum of healthcare services to local and foreign patients alike.
Tam Duc Heart Hospital
Specializing in cardiovascular care, Tam Duc Heart Hospital is renowned for its expertise in heart surgery and treatments, providing specialized care in one of the most critical medical fields.
L'Hôpital Français De Hanoï
This private French-Vietnamese hospital in Hanoi offers a blend of Western standards and local care, focusing on high-quality services with modern facilities for both local and expatriate patients.
These hospitals represent the best of Vietnam's healthcare sector, known for their cutting-edge technology,
The manual provides an overview of the use of the Lumina 3D-e device for magnetotherapy, which operates with low-frequency pulsed magnetic fields. It explains how these magnetic impulses affect cells, enhance microcirculation and metabolism, contributing to the reduction of pain, swelling, and muscle spasms while also promoting tissue healing. Additionally, it clarifies how to properly set up and use the device – from selecting the appropriate mode for home care (EASY) to more advanced options designed for clinical environments (CLINIC).
The manual includes safety guidelines that highlight proper handling of the device to prevent risks associated with incorrect usage. It also provides information on the device's technical parameters, such as frequency, pulse duration, and magnetic field intensity, along with a description of individual therapeutic programs that can be customized to meet the patient's needs.
Furthermore, details on different types of applicators – such as circular, flat, or localized – and their specific applications for targeted therapy are included. Emphasis is also placed on regular maintenance and inspection of the device to ensure its long-term effectiveness and safety during therapeutic use.
MEDIROM Healthcare Technologies Inc. Investor PresentationYohei Umezaki
Medirom is a health and wellness company providing preventive solutions through its 312 relaxation salons, Mobile App LAV, Wearable device MOTHER Bracelet
Preschool age nutritional requirements Dr Roopam Gupta PPT.pptxRoopamGupta17
“Preschool age child” means any child from three years of age to six years of age who is not attending school (elementary).
The RDA for energy as suggested by ICMR in 2020
1-3 Year:- 1010 Kcal/ day
4-6 Year:- 1360 Kcal/ day
Energy is required for growth and activity.
Insufficient food will not only result in under-nutrition in terms of inadequate weight gain but will also hinder growth.
Due to improper weaning practices, the child may not meet calorie and protein requirement leading to Protein Energy Malnutrition.
Insufficient calorie intake can lead to protein deficiency.
The RDA for protein as suggested by ICMR in 2020
1-3 Year:- 11.3 g/ day
4-6 Year:- 15.9 g/ day
The increase in muscle mass that must accompany bone growth requires positive nitrogen balance.
The increase in body size necessitates a larger vascular system to transport nutrients to the tissues.
Thus there is an increase in demand for nutrients needed in blood formation like protein, iron, folacin and pyridoxine.
Bone growth also creates a need for protein.
The RDA for calcium as suggested by ICMR in 2020
1-3 Year:- 500 mg/ day
4-6 Year:- 550 mg/ day
Calcium requirements of children is calculated on the basis of the amount of calcium accretion in the body.
This deposition is not uniform throughout growing period, but would be relatively greater during early childhood and during adolescence than during the other periods of growth.
Deficiency of calcium can affect the bones of growing children.
Milk is the best source of calcium.
Hence the diet of preschool child should include 1-2 glasses of milk per day.
The RDA for minimum level of visible fat in the diet of children as suggested by ICMR in 2020 is 25 g/ day.
Fat energy including invisible fat for children should be 25 per cent of total energy.
The RDA for iron as suggested by ICMR in 2020
1-3 Year:- 8 mg/ day
4-6 Year:-11 mg/ day
Between 1 to 6 years of age, the body iron content is doubled.
The absorbed iron requirements in children are very high in relation to their energy requirements.
To meet this increased demand for iron, iron-rich foods like rice-flakes, egg yolk and greens should be included in the diet.
The RDA for Vitamin A as suggested by ICMR in 2020
1-3 Year:- 390 microgram/ day
4-6 Year:- 510 microgram/ day
Deficiency of Vitamin A in children can cause Bitot’s spots, night blindness or in severe cases total blindness also.
Milk, eggs, carrots and green leafy vegetables should be included in the diet.
The daily allowances of B- vitamin requirements are based on energy intake.
Tooth decay or cavities are common in young children according to the researches.
This can occur in children whose integrity of tooth structure may be affected by the nutritional deficiency.
This disorder involves repeated or chronic ingestion of non-nutrient substances which may include plaster, charcoal, clay, wool, ashes, metal (pins, nails or blades), paint and earth.
The age of onset is usually 1-2 years.
Can You Explain the Effects and Severity of Measles? A Complete GuideVimalRocks1
Can You Explain the Effects and Severity of Measles?
Measles is a highly contagious viral infection that affects millions worldwide. But how severe is measles, and what effects does it have on the body? This SlideShare dives deep into everything you need to know about measles, from its symptoms to complications and prevention strategies.
What You’ll Learn in This Presentation:
✅ The causes and transmission of measles
✅ Early symptoms and warning signs
✅ How measles impacts different age groups
✅ Possible complications, including pneumonia and encephalitis
✅ Why vaccination is crucial for preventing outbreaks
Measles is more than just a rash and fever—it can lead to serious health issues, especially in young children and those with weakened immune systems. This SlideShare provides clear, easy-to-understand information that helps you recognize the risks and take preventive measures.
🔹 Why is this important?
Understanding the severity of measles helps in raising awareness, preventing misinformation, and encouraging timely vaccinations. Whether you're a parent, student, or health professional, this guide gives you valuable insights into the disease.
📌 Stay Informed. Stay Protected.
👉 Swipe through the slides to get a detailed breakdown of measles effects, severity, and ways to stay safe.
#Measles #HealthAwareness #Vaccination #MeaslesSymptoms #DiseasePrevention
Menopause and physiological changes during menopause.pptxRishika Rawat
Menopause is one point in a continuum of life stages for women and marks the end of their reproductive years. After menopause, a woman cannot become pregnant, except in rare cases when specialized fertility treatments are used.
Most women experience menopause between the ages of 45 and 55 years as a natural part of biological ageing. Menopause can also be a consequence of surgical or medical procedures.
Menopause is caused by the loss of ovarian follicular function and a decline in circulating blood estrogen levels.