Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation

Clin Case Rep. 2023 Nov 22;11(11):e8190. doi: 10.1002/ccr3.8190. eCollection 2023 Nov.

Abstract

Treatment of recurrent myelodysplastic syndrome (MDS) after hematopoietic cell transplantation (HCT) remains challenging. We present a 4-year-old girl experiencing early MDS relapse post-HCT treated with a multimodal strategy encompassing a second HCT and innovative targeted therapies. We underscore the potential of a comprehensive treatment approach in managing recurrent pediatric MDS.

Keywords: disease control; hematopoietic stem cell transplantation; myelodysplastic syndromes; relapse.

Publication types

  • Case Reports