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Five reasons why we are excited about structural biology:
It helps understand three-dimensional molecular architecture of proteins and nucleic acids at atomic resolution level
It uses biophysical methods to analyze proteins and their structures by employing Nuclear Magnetic Resonance (NMR), X-ray crystallography and Cryo-electron microscopy (Cryo-EM) techniques
It has revolutionized drug design
It helps us understand basic biological pathways mechanisms
It enlightens us on auto-immune diseases and how they are linked to hyper-activation of certain inflammasomes
Humayun Sharif is a structural biologist and biochemist by training. He uses advanced structural biology and biochemical techniques to study host-pathogen interaction and innate immune response.
