EON Network: February 2025 Newsletter |
The EON Network was established to facilitate communication between exercise oncology and oncology nutrition researchers and clinicians to achieve our joint goal of improving cancer treatment outcomes.
The EON Network monthly newsletter includes upcoming webinars, updates on exercise oncology and oncology nutrition related events, publications that may be of interest, and resources. This information is also available on the EON Network webpage. Past newsletters are archived.
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CANCELED: Upcoming Webinar (Thursday, February 20) |
The EON Network Webinar scheduled for Thursday, February 20 has been canceled.
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Highlighted Publication: "Timely reporting of patient-reported outcomes in cancer clinical trials: An ethical imperative."
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Blackstone EC, Efficace F, Meyerhardt JA, Abel GA. Timely reporting of patient-reported outcomes in cancer clinical trials: An ethical imperative. J Clin Oncol 2025 Jan 21:JCO2402021. Epub ahead of print. PMID: 39836934
Dr. Blackstone writes: “Patient-reported outcomes (PROs) are a critical component of evaluating cancer therapies in clinical trials because they provide insights into physical, social, and psychological impacts of treatment. While collection of these vital data has increased, recent analyses have shown that dissemination of PRO results from cancer trials occurs inconsistently. At the same time, cancer trials increasingly rely on surrogate outcomes such as progression-free survival to evaluate efficacy of new therapies. While this approach can make clinical trials faster and more cost-efficient, it also risks widespread use of therapies that may not make patients live longer or feel better. In this article we analyze how these two trends in contemporary clinical trials intersect and the ethical issues raised, providing recommendations to improve timely reporting of PRO data.”
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Highlighted Publication: "Metastatic breast cancer patients' preferences for exercise programs: a latent class analysis using data from a survey in five European countries."
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Sweegers MG, Depenbusch J, Aaronson NK, Hiensch AE, Wengström Y, Backman M, Gunasekara N, Clauss D, Belloso J, Lachowicz M, May AM, Steindorf K, Stuiver MM. Metastatic breast cancer patients' preferences for exercise programs: a latent class analysis using data from a survey in five European countries. Support Care Cancer 2024;33(1):39. PMID: 39694910
Dr. Stuiver writes: “This study is a secondary analysis of data from the multinational EU-funded PREFERABLE-PERSPECTIVE survey. We examined exercise preferences among metastatic breast cancer (MBC) patients and used Latent Class Analysis to identify subgroups with similar preferences for exercise type, intensity, frequency, session duration, and supervision.
"Based on data from 409 participants, we identified four subgroups. Nearly half of the respondents preferred moderate intensity, supervised exercise in a healthcare setting. These patients often had bone metastases. About a third favoured vigorous, supervised exercise. These patients were, on average, younger and had a higher education level. The third group preferred active walking and had fewer comorbidities. The smallest group preferred recreational walking and was, on average, older and less likely to be employed.
"Our findings show that patients with MBC are open to a variety of exercise interventions but also highlight the need for targeted education aiming to align patients’ exercise preferences with current exercise recommendations, particularly regarding resistance exercise. Implementing exercise programs within healthcare settings is advised to meet MBC patients understandable need for supervision.”
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Highlighted Publication: "Nutritional counseling during chemotherapy treatment: A systematic review of feasibility, safety, and efficacy."
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James S, Oppermann A, Schotz KM, Minotti MM, Rao GG, Kleckner IR, Baguley BJ, Kleckner AS. Nutritional counseling during chemotherapy treatment: A systematic review of feasibility, safety, and efficacy. Curr Oncol 2024;32(1):3. PMID: 39851919
Ms. James writes: “Nutritional support during chemotherapy can benefit patients physically and mentally. Current nutrition guidelines emphasize adequate protein, whole grains over refined sugars, and a variety of fruits and vegetables. However, we wanted to explore dietary programs during chemotherapy and assess the evidence for more specific nutrition recommendations.
"This study evaluated current research on nutrition during chemotherapy treatment with three key questions: 1) Can people change their diet despite the challenges of a cancer diagnosis and the demands of chemotherapy? 2) Are dietary programs safe during treatment? and 3) Do nutrition programs lead to specific health outcomes? Using three research databases, we identified 39 independent studies that have evaluated a nutrition program during chemotherapy.
"Studies tested the implementation of existing nutrition guidelines and other diets including the Mediterranean Diet, an anti-inflammatory diet, a plant-based high-protein diet, and diets with an added exercise program. Despite their differences, nearly all programs were possible during chemotherapy with minimal side effects. Many studies found that nutrition programs helped maintain nutritional status, increase quality of life, decrease fatigue, maintain weight, and even tolerate chemotherapy. Our lab is continuing to research how to optimize nutrition during and after treatment to minimize side effects of chemotherapy and promote healing.”
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Additional Publications of Interest
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Groarke JD, Crawford J, Collins SM, Lubaczewski S, Roeland EJ, Naito T, Hendifar AE, Fallon M, Takayama K, Asmis T, Dunne RF, Karahanoglu I, Northcott CA, Harrington MA, Rossulek M, Qiu R, Saxena AR. Ponsegromab for the treatment of cancer cachexia. N Engl J Med 2024;391(24):2291-2303. Epub 2024 Sep 14. PMID: 39282907
Brouwer CG, Tusscher MRT, de Roos BM, Gootjes EC, Buffart TE, Versteeg KS, Mast IH, Streppel MM, Werter IM, May AM, Verheul HMW, Buffart LM; AMICO Consortium. Experiences of patients with metastatic colorectal cancer participating in a supervised exercise intervention during chemotherapy. Support Care Cancer 2025;33(2):82. PMID: 39779537
Cormie P, Bradford A, Doran CM, Potts BA, Martin P, Chiswell M, Krishnasamy M. Willingness to pay for exercise oncology services: a mixed methods study. Support Care Cancer 2025;33(2):77. PMID: 39775110
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NIH/NCI Funding Opportunities |
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