MP faculty publications: August 2020

1. Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.

   Ni T, Gerard S, Zhao G, Dent K, Ning J, Zhou J, Shi J, Anderson-Daniels J, Li W, Jang S, Engelman AN, Aiken C, Zhang P
   Nat Struct Mol Biol. 2020 Aug 03;:

2. SERINC5 Inhibits HIV-1 Infectivity by Altering the Conformation of gp120 on HIV-1 Particles.

   Featherstone A, Aiken C
   J Virol. 2020 Aug 12;:

3. Leveraging bioengineering to assess cellular functions and communication within human fetal membranes.

   Eastman AJ, Noble KN, Pensabene V, Aronoff DM
   J Matern Fetal Neonatal Med. 2020 Aug 12;:1-13

4. The impact of Lactobacillus on group B streptococcal interactions with cells of the extraplacental membranes.

   Shiroda M, Aronoff DM, Gaddy JA, Manning SD
   Microb Pathog. 2020 Aug 20;:104463

5. A simplified method to produce mRNAs and functional proteins from synthetic double-stranded DNA templates.

   Tossberg JT, Esmond TM, Aune TM
   Biotechniques. 2020 Aug 20;:

6. Changes in peripheral and local tumor immunity after neoadjuvant chemotherapy reshape clinical outcomes in patients with breast cancer.

   Axelrod ML, Nixon MJ, Gonzalez-Ericsson PI, Bergman RE, Pilkinton MA, McDonnell WJ, Sanchez V, Opalenik S, Loi S, Zhou J, Mackay S, Rexer BN, Abramson VG, Jansen VM, Mallal SA, Donaldson J, Tolaney SM, Krop I, Garrido-Castro AC, Marotti JD, Shee K, Miller TW, Sanders M, Mayer IA, Salgado R, Balko JM
   Clin Cancer Res. 2020 Aug 21;:

7. Immune checkpoint inhibitor toxicities: systems-based approaches to improve patient care and research.

   Johnson DB, Reynolds KL, Sullivan RJ, Balko JM, Patrinely JR, Cappelli LC, Naidoo J, Moslehi JJ
   Lancet Oncol. 2020 Aug;21(8):e398-e404

8. The future of sepsis research: Time to think differently?

   Bastarache JA
   Am J Physiol Lung Cell Mol Physiol. 2020 Aug 05;:

9. Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis.

   Bechard ME, Smalling R, Hayashi A, Zhong Y, Word AE, Campbell SL, Tran AV, Weiss VL, Iacobuzio-Donahue C, Wellen KE, McDonald OG
   Nat Commun. 2020 Aug 13;11(1):4055

10. Evolution-guided mutagenesis of the cytoplasmic incompatibility proteins: Identifying CifA's complex functional repertoire and new essential regions in CifB.

    Shropshire JD, Kalra M, Bordenstein SR
    PLoS Pathog. 2020 Aug 19;16(8):e1008794

11. Quorum Sensing and Toxin Production in Staphylococcus aureus Osteomyelitis: Pathogenesis and Paradox.

    Butrico CE, Cassat JE
    Toxins (Basel). 2020 Aug 12;12(8):

12. Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity.

    Wang S, Raybuck A, Shiuan E, Cho SH, Wang Q, Brantley-Sieders DM, Edwards D, Allaman MM, Nathan J, Wilson KT, DeNardo D, Zhang S, Cook R, Boothby M, Chen J
    JCI Insight. 2020 Aug 06;5(15):

13. Novel Insights Into Tissue-Specific Biochemical Alterations in Pediatric Eosinophilic Esophagitis Using Raman Spectroscopy.

    Hiremath G, Locke A, Thomas G, Gautam R, Acra S, Correa H, Dellon ES, Mahadevan-Jansen A
    Clin Transl Gastroenterol. 2020 Jul;11(7):e00195

14. Racial differences in Helicobacter pylori CagA sero-prevalence in a consortium of adult cohorts in the United States.

    Varga MG, Butt J, Blot WJ, Le Marchand L, Haiman CA, Chen Y, Wassertheil-Smoller S, Tinker LF, Peek RM, Potter JD, Cover TL, Hyslop T, Zeleniuch-Jacquotte A, Berndt SI, Hildesheim A, Waterboer T, Pawlita M, Epplein M
    Cancer Epidemiol Biomarkers Prev. 2020 Aug 20;:

15. Mean Levels and Variability in Psychological Well-Being and Associations With Sleep in Midlife and Older Women.

    Leger KA, Blevins TR, Crofford LJ, Segerstrom SC
    Ann Behav Med. 2020 Aug 28;:

16. A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice.

    Fox JM, Huang L, Tahan S, Powell LA, Crowe JE, Wang D, Diamond MS
    PLoS Pathog. 2020 Aug 06;16(8):e1008743

17. Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.

    Dong J, Gilchuk I, Li S, Irving R, Goff MT, Turner HL, Ward AB, Carnahan RH, Crowe JE
    J Clin Invest. 2020 Aug 04;:

18. Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.

    Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE
    Cell Host Microbe. 2020 Aug 07;:

19. Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.

    Finn JA, Dong J, Sevy AM, Parrish E, Gilchuk I, Nargi R, Scarlett-Jones M, Reichard W, Bombardi R, Voss TG, Meiler J, Crowe JE
    Structure. 2020 Aug 06;:

20. Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.

    Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE, Van Hoeven N, Thackray LB, Carnahan RH
    Nat Biomed Eng. 2020 Aug 03;:

21. SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

    orbett KS, Edwards DK, Leist SR, Abiona OM, Boyoglu-Barnum S, Gillespie RA, Himansu S, Schäfer A, Ziwawo CT, DiPiazza AT, Dinnon KH, Elbashir SM, Shaw CA, Woods A, Fritch EJ, Martinez DR, Bock KW, Minai M, Nagata BM, Hutchinson GB, Wu K, Henry C, Bahi K, Garcia-Dominguez D, Ma L, Renzi I, Kong WP, Schmidt SD, Wang L, Zhang Y, Phung E, Chang LA, Loomis RJ, Altaras NE, Narayanan E, Metkar M, Presnyak V, Liu C, Louder MK, Shi W, Leung K, Yang ES, West A, Gully KL, Stevens LJ, Wang N, Wrapp D, Doria-Rose NA, Stewart-Jones G, Bennett H, Alvarado GS, Nason MC, Ruckwardt TJ, McLellan JS, Denison MR, Chappell JD, Moore IN, Morabito KM, Mascola JR, Baric RS, Carfi A, Graham BS
    Nature. 2020 Aug 05;:

22. Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.

    Banerjee A, Herring CA, Chen B, Kim H, Simmons AJ, Southard-Smith AN, Allaman MM, White JR, Macedonia MC, Mckinley ET, Ramirez Solano MA, Scoville EA, Liu Q, Wilson KT, Coffey RJ, Washington MK, Goettel JA, Lau KS
    Gastroenterology. 2020 Aug 20;:

23. Efavirenz Pharmacogenetics and Weight Gain following Switch to Integrase Inhibitor-containing Regimens.

    Leonard MA, Cindi Z, Bradford Y, Bourgi K, Koethe J, Turner M, Norwood J, Woodward B, Erdem H, Basham R, Baker P, Rebeiro PF, Sterling TR, Hulgan T, Daar ES, Gulick R, Riddler SA, Sinxadi P, Ritchie MD, Haas DW
    Clin Infect Dis. 2020 Aug 23;:

24. Pharmacogenetic interactions of rifapentine plus isoniazid with efavirenz or nevirapine.

    Haas DW, Podany AT, Bao Y, Swindells S, Chaisson RE, Mwelase N, Supparatpinyo K, Mohapi L, Gupta A, Benson CA, Baker P, Fletcher CV
    Pharmacogenet Genomics. 2020 Aug 17;:

25. CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation.

    Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC
    JCI Insight. 2020 Aug 20;5(16):

26. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy.

    Barone SM, Paul AGA, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM
    bioRxiv. 2020 Aug 01;:

27. Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model.

    Kumar A, Suryadevara NC, Wolf KJ, Wilson JT, Di Paolo RJ, Brien JD, Joyce S
    Sci Rep. 2020 Aug 05;10(1):13167

28. Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis.

    Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, Peter L, Chung MI, Taylor CJ, Jetter C, Raju L, Roberson J, Ding G, Wood L, Sucre JMS, Richmond BW, Serezani AP, McDonnell WJ, Mallal SA, Bacchetta MJ, Loyd JE, Shaver CM, Ware LB, Bremner R, Walia R, Blackwell TS, Banovich NE, Kropski JA
    Sci Adv. 2020 Jul;6(28):eaba1972

29. Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.

    Vilgelm AE, Bergdorf K, Wolf M, Bharti V, Shattuck-Brandt R, Blevins A, Jones C, Phifer C, Lee M, Lowe C, Hongo R, Boyd K, Netterville J, Rohde S, Idrees K, Bauer JA, Westover D, Reinfeld B, Baregamian N, Richmond A, Rathmell WK, Lee E, McDonald OG, Weiss VL
    iScience. 2020 Jul 24;23(8):101408

30. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism.

    Wu H, Herr D, MacIver NJ, Rathmell JC, Gerriets VA
    Int Immunopharmacol. 2020 Aug 28;88:106922

31. Population-based Analysis of Differences in Gastric Cancer Incidence Among Races and Ethnicities in Individuals Age 50 Years and Older.

    Shah SC, McKinley M, Gupta S, Peek RM, Martinez ME, Gomez SL
    Gastroenterology. 2020 Aug 04;:

32. COVID-19 diagnostics for resource-limited settings: Evaluation of "unextracted" qRT-PCR.

    Adams NM, Leelawong M, Benton A, Quinn C, Haselton FR, Schmitz JE
    J Med Virol. 2020 Jul 23;:

33. Cross-Comparison of a Chemiluminescent Platform and a Commercial Receptor Binding Domain-Based ELISA Assay for Detecting SARS-CoV-2 IgG.

    Antoine-Reid T, Malone J, Maris AS, White-Abell J, Schmitz JE
    J Appl Lab Med. 2020 Aug 04;:

34. Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone.

    Becker SH, Ulrich K, Dhabaria A, Ueberheide B, Beavers W, Skaar EP, Iyer LM, Aravind L, Jakob U, Darwin KH
    mBio. 2020 Aug 25;11(4):

35. Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare.

    Le NH, Peters K, Espaillat A, Sheldon JR, Gray J, Di Venanzio G, Lopez J, Djahanschiri B, Mueller EA, Hennon SW, Levin PA, Ebersberger I, Skaar EP, Cava F, Vollmer W, Feldman MF
    Sci Adv. 2020 Jul;6(30):eabb5614

36. Anacardic acid induces IL-33 and promotes remyelination in CNS.

    Ljunggren-Rose Å, Natarajan C, Matta P, Pandey A, Upender I, Sriram S
    Proc Natl Acad Sci U S A. 2020 Aug 17;:

37. A deliberate path toward diversity, equity, and inclusion within the ASCI.

    Ware LB, Collins KL, Hawley JB, Ahima RS
    J Clin Invest. 2020 Aug 24;:

38. Physiological and biological heterogeneity in COVID-19-associated acute respiratory distress syndrome.

    Ware LB
    Lancet Respir Med. 2020 Aug 27;:

39. Instrument gauge and type in uveal melanoma fine needle biopsy: implications for diagnostic yield and molecular prognostication.

    Klofas LK, Bogan CM, Coogan A, Schultenover SJ, Weiss VL, Daniels AB
    Am J Ophthalmol. 2020 Aug 17;:

40. Targeted education as a method for reinforcing Paris System criteria and reducing urine cytology atypia rates.

    Compton ML, Weiss VL, Barkan GA, Ely KA
    J Am Soc Cytopathol. 2020 Jul 15;:

41. An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.

    Brubaker DK, Kumar MP, Chiswick EL, Gregg C, Starchenko A, Vega PN, Southard-Smith AN, Simmons AJ, Scoville EA, Coburn LA, Wilson KT, Lau KS, Lauffenburger DA
    Sci Signal. 2020 Aug 04;13(643):