The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
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Department of Biochemistry |
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Modified unlocked nucleic acid (MUNA) mitigates off-target effects of small interfering RNAs. Nucleic Acids Research.
Shohei Mori* (Alnylam Pharmaceuticals), Martin Egli. -
Maximillian Osterberg* (Indiana University), Jeanette Critchlow, Tae Akizuki, Walter Chazin, Eric Skaar.
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LassoESM a tailored language model for enhanced lasso peptide property prediction. Nature Communications.
Xuenan Mi* (University of Illinois Urbana-Champaign), Douglas Mitchell*. -
Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms. Nucleic Acids Research.
Matthew Cranford*, Steven Dahmen, David Cortez, James Dewar*. -
The aflatoxin B 1-induced formamidopyrimidine adduct is repaired by transcription-coupled nucleotide excision repair in human cells. NAR Cancer.
Daniel Laverty* (Harvard T.H. Chan School of Public Health), Rachana Tomar, Michael Stone.
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Department of Cell and Developmental Biology |
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Diet gel-based oral drug delivery system for controlled dosing of small molecules for microglia depletion and inducible Cre recombination in mice. Lab Animal.
Joel Jovanovic*, Megan Stone, Samantha Dooyema, Yuankai Tao, Sabine Fuhrmann, Edward Levine*. -
Ultrafast Isolation of Synaptic Terminals From Rat Brain for Cryo-Electron Tomography Analysis. bio-protocol.
Rong Sun*, Qiangjun Zhou*.
Supported by the Cryo-EM Facility. - P4-ATPases control phosphoinositide membrane asymmetry and neomycin resistance. Nature Cell Biology.
Bhawik Jain*, H. Diessel Duan* (Van Andel Institute), Christina Valentine, Ariana Samiha, Todd Graham*.
Supported by the Cell Imaging Shared Resource.
College of Arts and Science: Researchers discover method to make traditional topical antibiotic safe to inject, potentially reducing antibiotic resistance
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Department of Molecular Physiology and Biophysics |
Department of Pharmacology |
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Investigating the role of rostral pedunculopontine nucleus M4 receptors in motor deficits and dyskinesia in hemiparkinsonian rats. Behavioural Brain Research.
Nicole Chambers* (Binghamton University), Ashley Centner, Craig Lindsley, P. Jeffrey Conn. -
Photoaffinity Ligand of Cystic Fibrosis Corrector VX-445 Identifies SCCPDH as an Off-Target. ACS Chemical Biology.
Minsoo Kim*, Kwangho Kim, Lea Barny, Toya Scaggs, Ian Romaine, KyuOk Jeon, Simona Codreanu, Stacy Sherrod, John McLean, Gary Sulikowski, Lars Plate*.
Supported by the Molecular Design and Synthesis Center. -
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene. Cancer Letters.
Alain Gobert*, Caroline Hawkins, Lydia Snyder, Kamery Williams, Daniel Barry, Margaret Allaman, Mohammad Asim, Kara McNamara, Shane Carey, Alberto Delgado, Regina Tyree, Kristie Rose, Yu Wang, Shilin Zhao, Olivier Boutaud, Irène Zagol-Ikapitte, M Blanca Piazuelo, M Kay Washington, Lori Coburn, Keith Wilson*.
Supported by the Mass Spectrometry Core Laboratory.
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Other basic biomedical papers |
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Enzyme miniaturization: Revolutionizing future biocatalysts. Biotechnology Advances.
Ning Ding*, Yaoyukun Jiang, Zihao Cheng, Xinchun Ran, Robbie Ge, Zhongyue Yang*. -
Short-term alterations in dietary amino acids override host genetic susceptibility and reveal mechanisms of Salmonella Typhimurium small intestine colonization (preprint). bioRxiv.
Nicolas Shealy*, Madi Baltagulov, Camila de Brito, Anna McGovern, Pollyana Castro, Alexandra Schrimpe-Rutledge, Simona Condreanu, Stacy Sherrod, Somnath Jana, Katerina Jones, Tamara Machado Ribeiro, John McLean, Daniel Beiting, Mariana Byndloss*.
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First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
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Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter.
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Vanderbilt University School of Medicine Basic Sciences
MRB III U-B1200 465 21st Avenue South
Nashville, TN 37240
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