The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
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Department of Biochemistry |
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Generation of antigen-specific paired-chain antibodies using large language models. Cell.
Perry Wasdin*, Alexis Janke, Toma Marinov, Gwen Jordaan, Olivia Powers, Matthew Vukovich, Clinton Holt, Alexandra Abu-Shmais, Ivelin Georgiev*.
VUMC News: AI can speed antibody design to thwart novel viruses: study -
Endocannabinoid oxygenation by prostaglandin H synthase-2: chemistry and biology. Journal of Biological Chemistry.
Carol Rouzer*, Lawrence Marnett*. -
CLIP2: a novel functional player in AQP5 trafficking dynamics and implications for Sjögren's disease. Cell Communication and Signaling.
Claudia D'Agostino* (Université Libre de Bruxelles), Zhen Wang, Kevin Schey.
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Functional Profiling of KCNE1 Variants Informs Population Carrier Frequency of Jervell and Lange-Nielsen Syndrome Type 2. Circulation: Genomic and Precision Medicine.
Carlos Vanoye* (Northwestern University Feinberg School of Medicine), Charles Sanders.
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Department of Cell and Developmental Biology |
Department of Molecular Physiology and Biophysics |
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Modeling protein conformational ensembles by guiding AlphaFold2 with Double Electron Electron Resonance (DEER) distance distributions. Nature Communications.
Tianqi Wu*, Richard Stein, Te-Yu Kao, Benjamin Brown, Hassane Mchaourab*.
Center for Structural Biology: A new spin (label) on Alphafold2: DEERfold guides Alphafold2 modeling with DEER distance distributions
- Ten rules for a structural bioinformatic analysis. PLOS Computational Biology.
Stephanie Wankowicz*. -
TREM2 expressing macrophages are not associated with prognostic markers or metabolic syndrome in early stage ER positive breast cancer. Scientific Reports.
Elysa Pierro*, Guadalupe Garcia, Violeta Sanchez, Paula Gonzalez-Ericsson, Barbara Fingleton, Alyssa Hasty, Brent Rexer*.
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Department of Pharmacology |
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The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR. Science.
Daniel Tabet* (University of Toronto), Atina Coté* (University of Toronto), Megan Lancaster, Andrew Glazer, Brett Kroncke, Dan Roden.
VUMC News: Genetic variation impact scores: A new tool for earlier heart disease detection -
HLA-B*58:01 and Risk of Allopurinol-Induced Severe Cutaneous Adverse Reactions in the US. JAMA Dermatology.
Chelsea Campbell*, Matthew Krantz, Alexis Yu, Elizabeth Phillips*.
VUMC News: New genetic marker found to predict severe gout drug reactions in US patients
Health Day: Two HLA Class I Alleles Independently Linked to Allopurinol-Induced SCARs -
Synaptobrevin-2 disease variants reveal spatial constraints within the presynaptic active zone. Proceedings of the National Academy of Sciences.
Natalie Guzikowski*, Elena Bagatelas, Ok-Ho Shin, Baris Alten, Ege Kavalali*.
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Other basic biomedical papers |
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First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
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Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter.
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Vanderbilt University School of Medicine Basic Sciences
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