MP faculty publications: April 2023

1. Identification of an Essential LolD-Like Protein in Helicobacter pylori

   McClain MS, Bryant KN, McDonald WH, Algood HMS, Cover TL.
   J Bacteriol. 2023 Apr 25;205(4):e0005223.

2. Convolutional neural network for biomarker discovery for triple negative breast cancer with RNA sequencing data

   Chen X, Balko JM, Ling F, Jin Y, Gonzalez A, Zhao Z, Chen J.
   Heliyon. 2023 Mar 23;9(4):e14819.

3. No rest for the wicked: Tumor cell senescence reshapes the immune microenvironment

   Hanna A, Balko JM.
   Cancer Cell. 2023 Mar 29:S1535-6108(23)00086-7.

4. Development of a Kinetic ELISA and Reactive B Cell Frequency Assay to Detect Respiratory Syncytial Virus Pre-Fusion F Protein-Specific Immune Responses in Infants

   Rolsma SL, Yoder SM, Nargi RS, Brady E, Jimenez-Truque N, Thomsen I, Kontos M, Carnahan RH, Sutton RE, Armstrong E, Dally L, Crowe JE, Edwards KM, Creech CB.
   J Pediatric Infect Dis Soc. 2023 Apr 8:piad019.

5. Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes

   Chen EC, Gilchuk P, Zost SJ, Ilinykh PA, Binshtein E, Huang K, Myers L, Bonissone S, Day S, Kona CR, Trivette A, Reidy JX, Sutton RE, Gainza C, Diaz S, Williams JK, Selverian CN, Davidson E, Saphire EO, Doranz BJ, Castellana N, Bukreyev A, Carnahan RH, Crowe JE Jr.
   Cell Rep. 2023 Apr 6;42(4):112370.

6. Glycan masking in vaccine design: Targets, immunogens and applications

   Martina CE, Crowe JE Jr, Meiler J.
   Front Immunol. 2023 Mar 23;14:1126034.

7. Convergent antibody responses are associated with broad neutralization of hepatitis C virus

   Skinner NE, Ogega CO, Frumento N, Clark KE, Yegnasubramanian S, Schuebel K, Meyers J, Gupta A, Wheelan S, Cox AL, Crowe JE Jr, Ray SC, Bailey JR.
   Front Immunol. 2023 Mar 24;14:1135841.

8. Risk Indicators of Sarcoidosis Evolution-Unified Protocol (RISE-UP): protocol for a multi-centre, longitudinal, observational study to identify clinical features that are predictive of sarcoidosis progression

   Drake WP, Hsia C, Samavati L, Yu M, Cardenas J, Gianella FG, Boscardin J, Koth LL.
   BMJ Open. 2023 Apr 3;13(4):e071607.

9. Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans

   Mateza S, Bradford Y, Maartens G, Sokhela S, Chandiwana NC, Venter WDF, Post FA, Ritchie MD, Haas DW, Sinxadi P.
   Pharmacogenet Genomics. 2023 Apr 24.

10. Sampling the rainbow

    Hadjifrangiskou M.
    Nat Chem Biol. 2023 Apr 13.

11. Immune Profiling Reveals Decreases in Circulating Regulatory and Exhausted T Cells in Human Hypertension

    Alexander MR, Dale BL, Smart CD, Elijovich F, Wogsland CE, Lima SM, Irish JM, Madhur MS.
    JACC Basic Transl Sci. 2023 Jan 4;8(3):319-336.

12. Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune response

    Currenti J, Simmons J, Oakes J, Gaudieri S, Warren CM, Gangula R, Alves E, Ram R, Leary S, Armitage JD, Smith RM, Chopra A, Halasa NB, Pilkinton MA, Kalams SA.
    Front Immunol. 2023 Mar 29;14:1133781.

13. Active Surveillance on the Prevalence of alpha-gal (galactose-alpha-1,3-galactose) syndrome in Middle Tennessee

    Liu K, Wofford RN, Newcomb DC, Stone CA Jr, Moncayo A.
    Ann Allergy Asthma Immunol. 2023 Apr 18:S1081-1206(23)00261-2.

14. The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis

    Duran-Aniotz C, Poblete N, Rivera-Krstulovic C, Ardiles ÁO, Díaz-Hung ML, Tamburini G, Sabusap CMP, Gerakis Y, Cabral-Miranda F, Diaz J, Fuentealba M, Arriagada D, Muñoz E, Espinoza S, Martinez G, Quiroz G, Sardi P, Medinas DB, Contreras D, Piña R, Lourenco MV, Ribeiro FC, Ferreira ST, Rozas C, Morales B, Plate L, Gonzalez-Billault C, Palacios AG, Hetz C.
    Mol Ther. 2023 Apr 4:S1525-0016(23)00161-2.

15. BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels

    Han D, Schaffner SH, Davies JP, Benton ML, Plate L, Nordman JT.
    bioRxiv [Preprint] 2023 Mar 28:2023.03.28.534572.

16. Neurons require glucose uptake and glycolysis in vivo

    Li H, Guglielmetti C, Sei YJ, Zilberter M, Le Page LM, Shields L, Yang J, Nguyen K, Tiret B, Gao X, Bennett N, Lo I, Dayton TL, Kampmann M, Huang Y, Rathmell JC, Heiden MV, Chaumeil MM, Nakamura K.
    Cell Rep. 2023 Apr 6;42(4):112335.

17. Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer

    Hinshaw DC, Benavides GA, Metge BJ, Swain CA, Kammerud SC, Alsheikh HA, Elhamamsy A, Chen D, Darley-Usmar V, Rathmell JC, Welner RS, Samant RS, Shevde LA.
    Cancer Immunol Res. 2023 Apr 14:OF1-OF16.

18. Comprehensive surface histology of fresh resection margins with rapid open-top light-sheet (OTLS) microscopy

    Gao G, Miyasato D, Barner LA, Serafin R, Bishop KW, Xie W, Glaser AK, Rosenthal EL, True LD, Liu JTC.
    IEEE Trans Biomed Eng. 2023 Jan 16;PP.

19. Early identification of life-threatening soft-tissue infection using dynamic fluorescence imaging: first-in-kind clinical study of first-pass kinetics

    Streeter SS, Ray GS, Bateman LM, Hebert KA, Bushee FE, Rodi SW, Gitajn IL, Ahn J, Singhal S, Martin ND, Bernthal NM, Lee C, Obremskey WT, Schoenecker JG, Elliott JT, Henderson ER.
    Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12361:123610B.

20. MALDI IMS-Derived Molecular Contour Maps: Augmenting Histology Whole-Slide Images

    Sharman K, Patterson NH, Migas LG, Neumann EK, Allen J, Gibson-Corley KN, Spraggins JM, Van de Plas R, Skaar EP, Caprioli RM.
    J Am Soc Mass Spectrom. 2023 Apr 16.

21. Pleiotropy promotes the evolution of inducible immune responses in a model of host-pathogen coevolution

    Martin RA, Tate AT.
    PLoS Comput Biol. 2023 Apr 6;19(4):e1010445.

22. TRPC6 inhibitor (BI 764198) to reduce risk and severity of ARDS due to COVID-19: a phase II randomised controlled trial

    Ware LB, Soleymanlou N, McAuley DF, Estrada V, Diaz GA, Lacamera P, Kaste R, Choi W, Gupta A, Welte T.
    Thorax. 2023 Apr 6:thorax-2022-219668.

23. Electrophilic reactive aldehydes as a therapeutic target in colorectal cancer prevention and treatment

    Gobert AP, Asim M, Smith TM, Williams KJ, Barry DP, Allaman MM, McNamara KM, Hawkins CV, Delgado AG, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Rathmacher JA, Wilson KT.
    Oncogene. 2023 Apr 10.

24. Low-Dose Erythropoietin Amplifies Beneficial Effects of Angiotensin II Blockade on Glomerulosclerosis

    Wang J, Matsushita K, Zhong J, Ma LJ, Yang HC, Fogo AB.
    Lab Invest. 2023 Feb;103(2):100015.

25. Compound Figure Separation of Biomedical Images: Mining Large Datasets for Self-supervised Learning

    Yao T, Qu C, Long J, Liu Q, Deng R, Tian Y, Xu J, Jha A, Asad Z, Bao S, Zhao M, Fogo AB, Landman BA, Yang H, Chang C, Huo Y.
    J Mach Learn Biomed Imaging. 2022 Aug;1:025.

26. Intestinal Lymphatic Dysfunction in Kidney Disease

    Zhong J, Kirabo A, Yang HC, Fogo AB, Shelton EL, Kon V.
    Circ Res. 2023 Apr 28;132(9):1226-1245.