Forwarded by the Los Angeles County Department of Public Health
| CDC Health Advisory
Influenza Update: Vaccinate, Test, and Administer Influenza Antivirals
January 5, 2026
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The California Department of Public Health (CDPH) issued a Health Advisory today regarding increasing influenza cases and hospital admissions statewide.
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Influenza cases and hospital admissions are increasing in California. A newly emerged influenza A virus strain, H3N2 subclade K, is circulating globally, including in California. The majority of influenza A specimens subtyped in California are H3N2. Current influenza vaccines are still expected to offer protection against severe disease.
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Administer 2025-26 influenza vaccine to anyone 6 months of age and older who has not yet received it.
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Test symptomatic patients as quickly as possible. Use rapid molecular (nucleic acid amplification detection) tests for outpatients, and RT-PCR and other influenza molecular tests for hospitalized patients to confirm diagnosis and guide timely treatment. Influenza A positive hospitalized patients, especially those in the ICU, should have specimens sent for subtyping.
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Initiate antiviral treatment without delay and ideally at point of care. Do not delay treatment while waiting for test results if influenza is suspected in high-risk patients. Treat immediately with oseltamivir or single-dose baloxavir based on recommendations for use. Treatment with influenza antivirals decreases the risk of serious illness and hospitalization in those at higher risk for severe disease. Flow chart for outpatient providers: “Don’t Delay, Start Antiviral for Suspected Influenza Immediately”.
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Stay aware of respiratory virus activity in your community by visiting the CDPH Respiratory Virus Dashboard this respiratory season. In LA County, visit LAC DPH RESPWatch.
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LAC DPH Influenza Resources
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- Immunizations
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Respiratory Illness Surveillance
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You can also copy and paste this link into your browser https://www.cdph.ca.gov/Programs/OPA/Pages/CAHAN/Influenza-Update.aspx
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To view this and other communications or to sign-up to receive LAHANs, please visit ph.lacounty.gov/lahan.
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