A clinical trial at Dana-Farber has kept Sharon DeCosta’s stage IV metastatic breast cancer stabilized for three years, allowing her a full life of traveling and doting on her three young grandchildren, with a fourth due in December. It may seem odd that DeCosta celebrates the anniversary of her diagnosis each year with a toast, until you realize the significance of the date. "I found out I had cancer on April 27, 2015 – my twenty-fifth wedding anniversary," she said.

For many people diagnosed with smoldering multiple myeloma, the shock of the diagnosis can be compounded by the distress of learning they won't receive treatment until physical symptoms of myeloma develop. Now, scientists and researchers have tracked the genomic changes that occur as smoldering multiple myeloma (SMM) advances to myeloma.