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Feature Story: Biostatistics and Computational Biology
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Mining “Big Data” to Improve Research Approaches in Cancer
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For years, the classic paradigm for evaluating new cancer drugs has been to compare two patient groups—one treated with an experimental approach and the other with the current standard of care—while keeping other variables, such as patient and disease characteristics, as similar as possible. This randomized, clinical trial approach remains the “gold standard” in clinical research, but like most ideals, translation into the “real world” setting is often more difficult and complicated. [more]
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Using Mathematics to Predict the Best Dose
Franziska Michor, PhD (DFCI) applies mathematical modeling to try to predict how cancers accumulate mutations and other changes and how these might affect response to treatment. Michor is the first to admit that her field of study is theoretical and complex; however, she points out that it has some highly clinically-relevant applications. [more]
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| Spotlight on Clinical Trials
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| Enzalutamide Plus EBRT as a Novel Treatment Approach in Intermediate Risk Prostate Cancer
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Community Practice Research Core
The Community Practice Research Core (CPRC) offers DF/HCC researchers an opportunity to work on cancer-related projects in real-world community settings. The CPRC is unique in offering DF/HCC investigators a connection to large, diverse patient populations; providing access to comprehensive computerized patient and provider data, including medical records, pathology and radiology reports, tumor registry data, and outpatient and hospitalization claims; and supporting developing research proposals within community practice settings. [more]
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| Three DF/HCC members have assumed leadership roles in recent months: Pier Paolo Pandolfi (BIDMC) was appointed to Deputy Associate Director for Basic Science; and Leif Ellisen (MGH) and Jean Zhao (DFCI) were both recently named Co-Leaders of the DF/HCC Breast Cancer Program.
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MembersCongratulations to the 29 individuals from our seven member institutions who have recently joined DF/HCC. Learn more about these scientists and their research interests.
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DF/HCC Members Receive Top Honors
Congratulations to the following DF/HCC faculty, who have been recognized for their outstanding research contributions recently:
Xandra Breakefield, William Silen Lifetime Achievement in Mentoring Award, HMS
Joan Brugge, Susan G. Komen® Brinker Award for Scientific Distinction in Basic Science
Patricia D'Amore, 2015 Proctor Medal
William Davids, Lemuel Shattuck Award from the Massachusetts Public Health Association (MPHA)
Matthew Gillman, U.S. Preventive Services Task Force
Edward Giovannucci, Commencement 2014 Faculty Award, Mentoring, HSPH
Ferenc Jolesz, A. Clifford Barger Excellence in Mentoring Award, HMS
Tomas Kirchhausen, elected to the European Molecular Biology Organization (EMBO)
Nancy Krieger, Commencement 2014 Faculty Award, Teaching Citations, HSPH
Douglas Kwon, Young Mentor Award, HMS
Timothy Mitchison, elected to the National Academy of Sciences
Marsha Moses, Fellow of the National Academy of Inventors (NAI)
Gary Ruvkun, 2014 Gruber Genetics Prize
Bernardo Sabatini, A. Clifford Barger Excellence in Mentoring Award, HMS
David Sinclair, named one of the world’s 100 most influential people, Time magazine
Kimberly Stegmaier, A. Clifford Barger Excellence in Mentoring Award, HMS
Clifford Tabin, William Silen Lifetime Achievement in Mentoring Award, HMS
Nancy Tarbell, ASTRO Gold Medal from the American Society for Radiation Oncology
K. ‘Vish’ Viswanath, Joseph W. Cullen Award from the American Society of Preventive Oncology; and the Dale E. Brashers Award from the National Communication Association
Christopher Walsh, 2014 Benjamin Franklin Medal in Chemistry named by the Franklin Institute Awards Program
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The 2014 Mazzone Awards Program Funds Prostate Cancer Research with Disparities Focus
Dana-Farber/Harvard Cancer Center and the Prostate Cancer Foundation announce two funding recipients for the 2014 Mazzone Awards Program. The A. David Mazzone Research Awards Program funds a series of collaborative and innovative cancer research, career development, community outreach, and training projects to address a range of needs in prostate cancer and Lupron-treatable diseases. [more]
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Bridge Project Funds Four New Research Teams
The Bridge Project, a collaboration between DF/HCC and the Koch Institute, is designed to bring bioengineering, advanced cancer science, and clinical oncology together to solve today’s most challenging problems in cancer research and care. This summer, the Bridge Project funded four new research teams, who will receive $375,000 (total costs) per team per year for up to two years ($750,000 total). [more]
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DF/HCC CURE Program Celebrates Thirteen Years of Success
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This year, 32 Scholars participated in the NCI Continuing Umbrella of Research Experiences (CURE) program, a hands-on research training experience for high school and college students from underrepresented populations. Many thanks to all of the DF/HCC mentors and Scientific Advisors who make the CURE training efforts possible. Please remember to join us for CURE Appreciation on November 4, 2014. View a complete list of 2014 CURE Program mentors.
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| Research Highlights From Our Member Institutions
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Dana-Farber/Harvard Cancer Center
Central Administration
450 Brookline Ave
Boston, MA 02115 |
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