The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
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Department of Biochemistry |
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Common and rare variant analyses reveal genetic factors underlying idiopathic pulmonary fibrosis and its shared aetiology with severe COVID-19. eBioMedicine.
Athanasios Kousathanas* (Genomics England), Taekyu Lee, James Christopher Tarr, Stephen Fesik. -
5-Hydroxymethylcytosine: a key epigenetic mark in cancer and chemotherapy response. Epigenetics & Chromatin.
Suhas Karat*. -
Lantibiotic-producing bacteria impact microbiome resilience and colonization resistance. Cell Host & Microbe.
Cody Cole* (University of Chicago), Shravan Dommaraju, Douglas Mitchell. -
A bypass gateway from cholesterol to sex steroid biosynthesis circumnavigates CYP17A1. Nature Communications.
Ziqi Zhu* (University of Miami Miller School of Medicine), Kevin McCarty, Tatiana Hargrove, Galina Lepesheva, F. Peter Guengerich. -
The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice. PLOS Pathogens.
Christopher Peritore-Galve*, Heather Kroh, John Shupe, Alyssa Ehni, Rubén Cano Rodríguez, Shannon Kordus, M. Kay Washington, D. Borden Lacy*. -
Cooling-Triggered Release of Celecoxib from Implantable Alginate-Soluplus Composite Devices. ACS Biomaterials Science & Engineering.
Romario Lobban*, Michael Carroll, Victoria Vest, Josh McCune, Sarah Hall, Fang Yu, Md. Jashim Uddin, Lawrence Marnett, Craig Duvall, Leon Bellan*.
School of Engineering: Innovative drug delivery mechanism triggered by cooling could provide targeted pain relief
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Department of Cell and Developmental Biology |
- CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations.
Xin Luo* (University of Michigan), Fan Feng, Alexander Hopkirk, Thai Pham, Thomas Bate, Diane Saunders, Shristi Shrestha, Jeffrey Spraggins, Jean-Philippe Cartailler, Marcela Brissova.
Supported by the Creative Data Solutions. -
Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention. American Journal of Human Genetics.
Qing Li*, Qingyuan Song*, Zhishan Chen*, Jie Ping, Wanqing Wen, Chao Li, Xiao-Ou Shu, Qiuyin Cai, Jirong Long, Bhuminder Singh, Ken Lau, Wei Zheng, Zhijun Yin*, Xingyi Guo*.
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Department of Molecular Physiology and Biophysics |
- Impact of common variants on brain gene expression from RNA to protein to schizophrenia risk. Nature Communications.
Qiuman Liang* (Central South University), Yi Jiang* (Central South University), Dan Zhou, Rui Chen, Bingshan Li. -
Crystallographic Ensembles Reveal the Structural Basis of Binding Entropy in SARS-CoV2 Macrodomain (preprint). bioRxiv.
Louella Seo, Ian Farran, Ahmed Aslam, Xinyun Li, Stephanie Wankowicz. - Prolonged Semaglutide Treatment Reveals Stage-Dependent Changes to Feeding Behavior and Metabolic Adaptations in Male Mice.
Harsh Shah*, Julio Ayala*.
Supported by the Vanderbilt Mouse Metabolic Phenotyping Center. -
Disruption of acyl-acyl carrier protein (acyl-ACP) synthetase in cyanobacteria impairs lipid remodeling as revealed by acyl-ACP measurements. Metabolic Engineering.
Juthamas Jaroensuk* (Donald Danforth Plant Science Center), Baltazar Zuniga, Hawkins Shepard, Bo Wang, Jody May, John McLean, Jamey Young.
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Department of Pharmacology |
- Discovery of VU6052254: A Novel, Potent M1 Positive Allosteric Modulator. ACS Chemical Neuroscience.
Julie Engers*, Joseph Bungard, Christopher Presley, Irene Zagol-Ikapitte, Katherine Watson, Sichen Chang, Jonathan Dickerson, Analisa Thompson Gray, Michael Bubser, Jerri Rook, Hyekyung Cho, Valerie Kramlinger, Olivier Boutaud, Carrie Jones, P. Jeffrey Conn, Darren Engers, Craig Lindsley*. -
Impact of distinct neurotransmitter release modes on neuronal signaling. Molecular Psychiatry.
Kevin Zhang*, Lisa Monteggia, Ege Kavalali*. -
Ultra-large library screening with an evolutionary algorithm in Rosetta (REvoLd). Communications Chemistry.
Paul Eisenhuth* (Leipzig University), Rocco Moretti, Jens Meiler.
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Other basic biomedical papers |
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First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
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Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter.
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Vanderbilt University School of Medicine Basic Sciences
MRB III U-B1200 465 21st Avenue South
Nashville, TN 37240
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