MP faculty publications: October 2023

1. Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus

   Padron A, Prakash P, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C
   J Virol. 2023 Oct 16:e0073223.

2. Accuracy and Reliability of Chatbot Responses to Physician Questions

   Goodman RS, Patrinely JR, Stone CA Jr, Zimmerman E, Donald RR, Chang SS, Berkowitz ST, Finn AP, Jahangir E, Scoville EA, Reese TS, Friedman DL, Bastarache JA, van der Heijden YF, Wright JJ, Ye F, Carter N, Alexander MR, Choe JH, Chastain CA, Zic JA, Horst SN, Turker I, Agarwal R, Osmundson E, Idrees K, Kiernan CM, Padmanabhan C, Bailey CE, Schlegel CE, Chambless LB, Gibson MK, Osterman TJ, Wheless LE, Johnson DB.
   JAMA Netw Open. 2023 Oct 2;6(10):e2336483

3. Differential adenine methylation analysis reveals increased variability in 6mA in the absence of methyl-directed mismatch repair

   Stone CJ, Boyer GF, Behringer MG.
   mBio. 2023 Oct 5:e0128923.

4. A purine salvage bottleneck leads to bacterial adenine cross-feeding

   Chuang YC, Haas NW, Pepin R, Behringer M, Oda Y, LaSarre B, Harwood CS, McKinlay JB.
   bioRxiv [Preprint]. 2023 Oct 17:2023.10.17.562681.

5. Bacteria- and Fungus-derived PAMPs Induce Innate Immune Memory via Similar Functional, Metabolic and Transcriptional Adaptations

   McBride MA, Stothers CL, Fensterheim BA, Caja KR, Owen AM, Hernandez A, Bohannon JK, Patil NK, Ali S, Dalal S, Rahim M, Trenary IA, Young JD, Williams DL, Sherwood ER.
   J Leukoc Biol. 2023 Oct 4:qiad120.

6. Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

   Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, David HE, Torres TP, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Folta-Stogniew E, Yang ZJ, Skaar EP, Byndloss MX, Chazin WJ, Zhu W.
   Cell Host Microbe. 2023 Oct 11;31(10):1639-1654.e10.

7. Turicibacterales protect mice from severe Citrobacter rodentium infection

   Hoek KL, McClanahan KG, Latour YL, Shealy N, Piazuelo MB, Vallance BA, Byndloss MX, Wilson KT, Olivares-Villagómez D
   Infect Immun. 2023 Oct 6:e0032223.

8. Developing a Prototype Pathogen Plan and Research Priorities for the Alphaviruses

   Powers AM, Williamson LE, Carnahan RH, Crowe JE Jr, Hyde JL, Jonsson CB, Nasar F, Weaver SC.
   J Infect Dis. 2023 Oct 18;228(Suppl 6):S414-S426.

9. Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin

   Santos RI, Ilinykh PA, Pietzsch CA, Ronk AJ, Huang K, Kuzmina NA, Zhou F, Crowe JE, Bukreyev A.
   Cell Rep. 2023 Oct 17;42(10):113254.

10. Identification of a functional peptide of a probiotic bacterium-derived protein for the sustained effect on preventing colitis

    Kaur H, Ali SA, Short SP, Williams CS, Goettel JA, Washington MK, Peek RM Jr, Acra SA, Yan F.
    Gut Microbes. 2023 Dec;15(2):2264456.

11. Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients

    Long JJ, Motter JD, Jackson KR, Chen J, Orandi BJ, Montgomery RA, Stegall MD, Jordan SC, Benedetti E, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Verbesey JE, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Wellen JR, Bozorgzadeh A, Gaber AO, Heher EC, Weng FL, Djamali A, Helderman JH, Concepcion BP, Brayman KL, Oberholzer J, Kozlowski T, Covarrubias K, Massie AB, McAdams-DeMarco MA, Segev DL, Garonzik-Wang JM.
    Am J Transplant. 2023 Sep 23:S1600-6135(23)00698-6.

12. Identification of brominated proteins in renal extracellular matrix: Potential interactions with peroxidasin

    Ivanov SV, Rose KL, Colon S, Vanacore RM, Hudson BG, Bhave G, Voziyan P.
    Biochem Biophys Res Commun. 2023 Nov 12;681:152-156.

13. Collagen IV of basement membranes: III. Chloride pressure is a primordial innovation that drives and maintains the assembly of scaffolds

    Boudko SP, Pedchenko VK, Pokidysheva EN, Budko AM, Baugh R, Coates PT, Fidler AL, Hudson HM, Ivanov SV, Luer C, Pedchenko T, Preston RL, Rafi M, Vanacore R, Bhave G, Hudson JK, Hudson BG; Aspirnauts
    J Biol Chem. 2023 Oct 3:105318.

14. Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila

    Summers JA, Yarbrough M, Liu M, McDonald WH, Hudson BG, Pastor-Pareja JC, Boudko SP
    J Biol Chem. 2023 Oct 25:105394.

15. Reply to "Letter responding to performance of updated Enterobacterales piperacillin-tazobactam breakpoints on the MicroScan antimicrobial susceptibility testing system"

    Humphries RM, Abbott AN, Alby K, Dien Bard J, Harrington AT, Mathers AJ, Simner PJ.
    J Clin Microbiol. 2023 Oct 12:e0069123

16. The Durability of Antibody Responses of Two Doses of High-Dose Relative to Two Doses of Standard-Dose Inactivated Influenza Vaccine in Pediatric Hematopoietic Cell Transplant Recipients: A Multi-Center Randomized Controlled Trial

    Schuster JE, Hamdan L, Dulek DE, Kitko CL, Batarseh E, Haddadin Z, Stewart LS, Stahl A, Potter M, Rahman H, Kalams SA, Bocchini CE, Moulton EA, Coffin SE, Ardura MI, Wattier RL, Maron G, Grimley M, Paulsen G, Harrison CJ, Freedman JL, Carpenter PA, Englund JA, Munoz FM, Danziger-Isakov L, Spieker AJ, Halasa NB
    Clin Infect Dis. 2023 Oct 6:ciad534.

17. Modulating microbiome-immune axis in the deployment-related chronic diseases of Veterans: report of an expert meeting

    Sun J, Ince MN, Abraham C, Barrett T, Brenner LA, Cong Y, Dashti R, Dudeja PK, Elliott D, Griffith TS, Heeger PS, Hoisington A, Irani K, Kim TK, Kapur N, Leventhal J, Mohamadzadeh M, Mutlu E, Newberry R, Peled JU, Rubinstein I, Sengsayadeth S, Tan CS, Tan XD, Tkaczyk E, Wertheim J, Zhang ZJ.
    Gut Microbes. 2023 Dec;15(2):2267180.

18. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling

    Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E.
    Nat Commun. 2023 Oct 5;14(1):6173.

19. Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo

    Kordus SL, Kroh HK, Rodríguez RC, Shrem RA, Peritore-Galve FC, Shupe JA, Wadzinski BE, Lacy DB, Spiller BW.
    PLoS Pathog. 2023 Oct 23;19(10):e1011496.

20. Identifying the effectiveness of 3D culture systems to recapitulate breast tumor tissue in situ

    Ludwik KA, Greathouse FR, Han S, Stauffer K, Brenin DR, Stricker TP, Lannigan DA
    Cell Oncol (Dordr). 2023 Sep 30

21. Characterizing the T Cell Repertoire in the Proximal Airway in Health and Disease

    Clark EA, Talatala ERR, Ye W, Davis RJ, Collins SL, Hillel AT, Ramirez-Solano M, Sheng Q, Wanjalla CN, Mallal SA, Gelbard A.
    Laryngoscope. 2023 Oct 3.

22. Minimal in-school SARS-CoV-2 transmission with strict mitigation protocols at two independent schools in Nashville, TN

    Peetluk LS, Rebeiro PF, Edwards KM, Banerjee R, Mallal SA, Aronoff DM, Lipworth L, Katz SE.
    medRxiv [Preprint]. 2021 Nov 10:2021.11.09.21266140.

23. An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism

    Shelton CD, Sing E, Mo J, Shealy NG, Yoo W, Thomas J, Fitz GN, Castro PR, Hickman TT, Torres TP, Foegeding NJ, Zieba JK, Calcutt MW, Codreanu SG, Sherrod SD, McLean JA, Peck SH, Yang F, Markham NO, Liu M, Byndloss MX.
    Cell Host Microbe. 2023 Oct 11;31(10):1604-1619.e10.

24. Response to Comment on Russell et al. Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care 2023;46:1005-1013

    Russell WE, Moore DJ, Herold KC.
    Diabetes Care. 2023 Nov 1;46(11):e210-e211.

25. Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease

    Foer D, Amin T, Nagai J, Tani Y, Feng C, Liu T, Newcomb DC, Lai J, Hayashi H, Snyder WE, McGill A, Lin A, Laidlaw TM, Niswender KD, Boyce JA, Cahill KN.
    J Immunol. 2023 Oct 23:ji2300102.

26. Effects of pasteurization on osteopontin concentrations in human breastmilk

    McClanahan KG, Reese J, Weitkamp JH, Olivares-Villagómez D.
    Pediatr Res. 2023 Oct 13.

27. Targeting hypoxia-inducible factor-1 alpha suppresses Helicobacter pylori-induced gastric injury via attenuation of both cag-mediated microbial virulence and proinflammatory host responses

    Noto JM, Piazuelo MB, Romero-Gallo J, Delgado AG, Suarez G, Akritidou K, Girod Hoffman M, Roa JC, Taylor CT, Peek Jr
    Gut Microbes. 2023 Dec;15(2):2263936.

28. Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial

    Vockley J, Sondheimer N, Puurunen M, Diaz GA, Ginevic I, Grange DK, Harding C, Northrup H, Phillips JA 3rd, Searle S, Thomas JA, Zori R, Denney WS, Ernst SL, Humphreys K, McWhorter N, Kurtz C, Brennan AM.
    Nat Metab. 2023 Oct;5(10):1685-1690.

29. Probable digenic inheritance of Diamond-Blackfan anemia

    Furuta Y, Tinker RJ, Gulsevin A, Neumann SM, Hamid R, Cogan JD, Rives L, Liu Q, Chen HC, Joos KM, Phillips JA 3rd
    Am J Med Genet A. 2023 Oct 27.

30. Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants

    McDonald EF, Oliver KE, Schlebach JP, Meiler J, Plate L.
    bioRxiv [Preprint]. 2023 Oct 9:2023.10.05.561147

31. The glucose transporter 2 regulates CD8+ T cell function via environment sensing

    Fu H, Vuononvirta J, Fanti S, Bonacina F, D'Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi MP, Grevitt P, Sheikh MH, Solito E, Godinho SA, Bombardieri M, Smith DM, Cooper D, Iqbal AJ, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD, Marelli-Berg FM.
    Nat Metab. 2023 Oct 26.

32. Utility of iliac crest tetracycline-labelled bone biopsy in osteoporosis and metabolic bone disease: An evaluation of 95 cases over a period of 25 years

    Colazo JM, Quirion J, Judice AD, Halpern J, Schwartz HS, Tanner SB, Lawrenz JM, Dahir KM, Holt GE.
    Bone Rep. 2023 Sep 24;19:101715.

33. Restriction of Arginine Induces Antibiotic Tolerance in Staphylococcus aureus

    Freiberg JA, Ruiz VMR, Green ER, Skaar EP.
    bioRxiv [Preprint]. 2023 Oct 12:2023.10.12.561972.

34. Inhibition of SUMOylation promotes remyelination and reduces IL-17 mediated autoimmune inflammation: Novel approach toward treatment of inflammatory CNS demyelinating disease

    Kim KW, Ljunggren-Rose Å, Matta P, Toki S, Sriram S.
    J Neuroimmunol. 2023 Oct 4;384:578219.

35. Pleiotropy alleviates the fitness costs associated with resource allocation trade-offs in immune signaling networks

    Martin R, Tate AT
    bioRxiv [Preprint]. 2023 Oct 10:2023.10.06.561276.

36. The Utility of Human Milk Oligosaccharides against Group B Streptococcus Infections of Reproductive Tissues and Cognate Adverse Pregnancy Outcomes

    Moore RE, Spicer SK, Lu J, Chambers SA, Noble KN, Lochner J, Christofferson RC, Vasco KA, Manning SD, Townsend SD, Gaddy JA.
    ACS Cent Sci. 2023 Aug 9;9(9):1737-1749.

37. NKG2A is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple Negative Breast Cancer

    Taylor BC, Sun X, Gonzalez-Ericsson PI, Sanchez V, Sanders ME, Wescott EC, Opalenik SR, Hanna A, Chou ST, Van Kaer L, Gomez H, Isaacs C, Ballinger TJ, Santa-Maria CA, Shah PD, Dees EC, Lehmann BD, Abramson VG, Pietenpol JA, Balko JM
    Cancer Discov. 2023 Oct 4

38. Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism

    You CL, Lee SJ, Lee J, Vuong TA, Lee HY, Jeong SY, Alishir A, Walker AS, Bae GU, Kim KH, Kang JS.
    J Extracell Vesicles. 2023 Nov;12(11):e12366.

39. MICB Genomic Variant is Associated with NKG2D-mediated Acute Lung Injury and Death

    Aguilar OA, Qualls AE, Gonzalez-Hinojosa MDR, Obeidalla S, Kerchberger VE, Tsao T, Singer JP, Looney MR, Raymond W, Hays SR, Golden JA, Kukreja J, Shaver CM, Ware LB, Christie J, Diamond JM, Lanier LL, Greenland JR, Calabrese DR; LTOG Investigators.
    Am J Respir Crit Care Med. 2023 Oct 25

40. Evolving approaches in paediatric thyroid cytopathology: A review

    Loberg MA, Tigue ML, Gallant JN, Wang H, Canberk S, Weiss VL.
    Cytopathology. 2023 Sep 27.

41. Hashimoto's Thyroiditis and the Risk of Papillary Thyroid Cancer in Children

    Gallant JN, Weiss VL, Chen SC, Liang J, Belcher RH, Ye F, Correa H, Wang H.
    Cancers (Basel). 2023 Oct 9;15(19):4902.

42. Impact of comorbidities on immediate post-operative complications in oral cavity free flap patients

    Ye W, Guo KS, Gallant JN, Stevens MN, Weiss VL, Bendfeldt GA, O'Brien MT, Rosenthal EL, Netterville JL, Mannion K, Langerman AJ, Sinard RJ, Topf MC, Rohde SL.
    Am J Otolaryngol. 2023 Sep 29;45(1):104068.

43. BRD4 regulates glycolysis-dependent Nos2 expression in macrophages upon H. pylori infection

    Modi N, Chen Y, Dong X, Hu X, Lau GW, Wilson KT, Peek RM Jr., Chen LF.
    Cell Mol Gastroenterol Hepatol. 2023 Oct 9:S2352-345X(23)00180-7.

44. A Specialized Epithelial Cell Type Regulating Mucosal Immunity and Driving Human Crohn's Disease

    Li J, Simmons AJ, Chiron S, Ramirez-Solano MA, Tasneem N, Kaur H, Xu Y, Revetta F, Vega PN, Bao S, Cui C, Tyree RN, Raber LW, Conner AN, Beaulieu DB, Dalal RL, Horst SN, Pabla BS, Huo Y, Landman BA, Roland JT, Scoville EA, Schwartz DA, Washington MK, Shyr Y, Wilson KT, Coburn LA, Lau KS, Liu Q.
    bioRxiv [Preprint]. 2023 Oct 2:2023.09.30.560293.

45. Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations

    Jimenez L, Barman B, Jung YJ, Cocozza L, Krystofiak E, Saffold C, Vickers KC, Wilson JT, Dawson TR, Weaver AM.
    J Extracell Vesicles. 2023 Nov;12(11):e12366