MP faculty publications: November 2023

1. Essential role of Helicobacter pylori apolipoprotein N-acyltransferase (Lnt) in stomach colonization

   Jung MS, Piazuelo MB, Brackman LC, McClain MS, Algood HMS.
   Infect Immun. 2023 Nov 8:e0036923

2. IL-17 receptor A functions to help maintain barrier integrity and limit activation of immunopathogenic response to H. pylori infection

   Brackman LC, Dixon BREA, Bernard M, Revetta F, Cowell RP, Meenderink LM, Washington MK, Piazuelo MB, Algood HMS
   Infect Immun. 2023 Nov 28:e0029223.

3. Next-generation phenotyping: introducing phecodeX for enhanced discovery research in medical phenomics

   Shuey MM, Stead WW, Aka I, Barnado AL, Bastarache JA, Brokamp E, Campbell M, Carroll RJ, Goldstein JA, Lewis A, Malow BA, Mosley JD, Osterman T, Padovani-Claudio DA, Ramirez A, Roden DM, Schuler BA, Siew E, Sucre J, Thomsen I, Tinker RJ, Van Driest S, Walsh C, Warner JL, Wells QS, Wheless L, Bastarache L
   Bioinformatics. 2023 Nov 1;39(11):btad655.

4. Cell-free hemoglobin triggers macrophage cytokine production via TLR4 and MyD88

   Schaaf KR, Landstreet SR, Pugazenthi S, Qian EY, Putz ND, Siderova T, Owen AM, Bohannon JK, Ware LB, Bastarache JA, Shaver CM
   Am J Physiol Lung Cell Mol Physiol. 2023 Nov 22

5. Nitrate-mediated luminal expansion of Salmonella Typhimurium is dependent on the ER stress protein CHOP

   Sweet LA, Kuss-Duerkop SK, Byndloss MX, Keestra-Gounder AM
   bioRxiv [Preprint]. 2023 Nov 3:2023.11.03.565559.

6. Plasma Cell Differentiation, Antibody Quality, and Initial Germinal Center B Cell Population Depend on Glucose Influx Rate

   Brookens SK, Cho SH, Paik Y, Meyer K, Raybuck AL, Park C, Greenwood DL, Rathmell JC, Boothby MR
   J Immunol. 2023 Nov 13:ji2200756.

7. Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination

   Munt JE, Henein S, Adams C, Young E, Hou YJ, Conrad H, Zhu D, Dong S, Kose N, Yount B, Meganck RM, Tse LPV, Kuan G, Balmaseda A, Ricciardi MJ, Watkins DI, Crowe JE Jr, Harris E, DeSilva AM, Baric RS
   Cell Host Microbe. 2023 Nov 8;31(11):1850-1865.e5.

8. Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology

   Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE Jr., Van Rompay KKA, Lovalenti P, Vu Truong, Forthal DN, Haigwood NL.
   Nat Commun. 2023 Nov 3;14(1):7062.

9. SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes

   Wall SC, Suryadevara N, Kim C, Shiakolas AR, Holt CM, Irbe EB, Wasdin PT, Suresh YP, Binshtein E, Chen EC, Zost SJ, Canfield E, Crowe JE Jr, Thompson-Arildsen MA, Sheward DJ, Carnahan RH, Georgiev IS
   Cell Rep Med. 2023 Nov 21;4(11):101267.

10. A mechanism for hereditary angioedema caused by a methionine-379 to lysine substitution in kininogens

    Dickeson SK, Kumar S, Sun MF, Litvak M, He TZ, Phillips DR, Roberts ET, Feener EP, Law RHP, Gailani D.
    Blood. 2023 Nov 22:blood.2023022254.

11. Negative Binomial Mixture Model for Identification of Noise in Antigen-Specificity Predictions by LIBRA-seq

    Wasdin PT, Abu-Shmais AA, Irvin MW, Vukovich MJ, Georgiev IS.
    bioRxiv [Preprint]. 2023 Oct 19:2023.10.13.562258

12. Pharmacogenetics of weight gain following switch from efavirenz- to integrase inhibitor-containing regimens

    Wu K, Koethe J, Hulgan T, Brown T, Bares SH, Tassiopoulos K, Lake JE, Leonard M, Samuels DC, Erlandson K, Haas DW.
    Pharmacogenet Genomics. 2023 Nov 1.

13. Collagen IV of basement membranes: II. Emergence of collagen IVα345 enabled the assembly of a compact GBM as an ultrafilter in mammalian kidneys

    Pokidysheva EN, Redhair N, Ailsworth O, Page-McCaw P, Rollins-Smith L, Jamwal VS, Ohta Y, Bächinger HP, Murawala P, Flajnik M, Fogo AB, Abrahamson D, Hudson JK, Boudko SP, Hudson BG.
    J Biol Chem. 2023 Nov 15:105459.

14. Mechanism of peroxidasin inactivation in hyperglycemia: Heme damage by reactive oxygen species

    Ivanov SV, Rose KL, Colon S, Hudson BG, Bhave G, Voziyan P.
    Biochem Biophys Res Commun. 2023 Dec 31;689:149237.

15. Underrepresentation of activating KIR gene expression in single-cell RNA-seq data is due to KIR gene misassignment

    Alves E, Chopra A, Ram R, Currenti J, Kalams SA, Mallal SA, Phillips EJ, Gaudieri S.
    Eur J Immunol. 2023 Nov 9:e2350590.

16. LAIR-1 agonism as a therapy for acute myeloid leukemia

    Lovewell RR, Hong J, Kundu S, Fielder CM, Hu Q, Kim KW, Ramsey HE, Gorska AE, Fuller LS, Tian L, Kothari P, Paucarmayta A, Mason EF, Meza I, Manzanarez Y, Bosiacki J, Maloveste K, Mitchell N, Barbu EA, Morawski A, Maloveste S, Cusumano Z, Patel SJ, Savona MR, Langermann S, Myint H, Flies DB, Kim TK.
    J Clin Invest. 2023 Nov 15;133(22):e169519

17. Loss of p73 Expression Contributes to Chronic Obstructive Pulmonary Disease

    Richmond BW, Marshall CB, Blackburn JB, Tufenkjian TS, Lehmann BD, Han W, Newcomb D, Gutor SS, Hunt RP, Michell DL, Vickers KC, Polosukhin VV, Blackwell TS, Pietenpol JA.
    Am J Respir Crit Care Med. 2023 Nov 6.

18. Flavinated SDHA underlies the change in intrinsic optical properties of oral cancers

    Marumo T, Maduka CV, Ural E, Apu EH, Chung SJ, Tanabe K, van den Berg NS, Zhou Q, Martin BA, Miura T, Rosenthal EL, Shibahara T, Contag CH.
    Commun Biol. 2023 Nov 9;6(1):1134.

19. Clinical Laboratory Experiences During the Coronavirus Disease 2019 Pandemic

    Humphries R, Sefers S, Schmitz J, Seegmiller A.
    Clin Infect Dis. 2023 Nov 2:ciad622.

20. Symptoms, viral loads, and rebound among COVID-19 outpatients treated with nirmatrelvir/ritonavir compared to propensity score matched untreated individuals

    Smith-Jeffcoat SE, Biddle JE, Talbot HK, Morrisey KG, Stockwell MS, Maldonado Y, McLean HQ, Ellingson KD, Bowman NM, Asturias E, Mellis AM, Johnson S, Kirking HL, Rolfes MAR, Olivo V, Merrill L, Battan-Wraith S, Sano E, McLaren SH, Vargas CY, Goodman S, Sarnquist CC, Govindaranjan P, Petrie JG, Belongia EA, Ledezma K, Pryor K, Lutrick K, Bullock A, Yang A, Haehnel Q, Rao S, Zhu Y, Schmitz J, Hart K, Grijalva CG, Salvatore PP.
    Clin Infect Dis. 2023 Nov 14:ciad696.

21. Clinical Outcomes and Associated Pathologies Following Pediatric Traumatic Hip Dislocations: A Systematic Review of the Literature

    Baumann AN, Ndjonko LCM, Schoenecker JG, Baldwin KD.
    J Pediatr Orthop. 2023 Nov 10.

22. Growth factor free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia

    Curry CW, Sturgeon SM, O'Grady BJ, Yates A, Kjar A, Paige H, Mowery LS, Katdare KA, Patel R, Mlouk K, Stiefbold MR, Vafaie-Partin S, Kawabata A, McKee R, Moore-Lotridge S, Hawkes A, Kusunose J, Gibson-Corley KN, Schmeckpeper J, Schoenecker JG, Caskey CF, Lippmann ES.
    Biomaterials. 2023 Nov 13;303:122397.

23. CRP Predicts the Need to Escalate Care After Initial Debridement for Musculoskeletal Infection

    Moore-Lotridge SN, Daryoush JR, Wollenman CC, Gibian JT, Johnson SR, Thomsen IP, Schoenecker JG.
    J Pediatr Orthop. 2023 Nov 24.

24. Clostridioides difficile ferrosome organelles combat nutritional immunity

    Pi H, Sun R, McBride JR, Kruse ARS, Gibson-Corley KN, Krystofiak ES, Nicholson MR, Spraggins JM, Zhou Q, Skaar EP.
    Nature. 2023 Nov 15.

25. Engineering Therapeutic Monoclonal Antibodies

    Stone CA Jr, Spiller BW, Smith SA.
    J Allergy Clin Immunol. 2023 Nov 21:S0091-6749(23)01476-8

26. Environmental Toxicant Exposure Paralyzes Human Placental Macrophage Responses to Microbial Threat

    Stephens VR, Moore RE, Spicer SK, Talbert JA, Lu J, Chinni R, Chambers SA, Townsend SD, Manning SD, Rogers LM, Aronoff DM, Vue Z, Neikirk K, Hinton AO Jr, Damo SM, Noble KN, Eastman AJ, McCallister MM, Osteen KG, Gaddy JA.
    ACS Infect Dis. 2023 Nov 13.

27. Ascorbate protects human kidney organoids from damage induced by cell-free hemoglobin

    Bejoy J, Farry JM, Qian ES, Dearing CH, Ware LB, Bastarache JA, Woodard LE.
    Dis Model Mech. 2023 Nov 9:dmm.050342.

28. Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A

    Barman B, Ramirez M, Dawson TR, Liu Q, Weaver AM.
    Proteomics. 2023 Nov 5:e2300099.

29. Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells

    Jimenez L, Stolzenbach V, Ozawa PMM, Ramirez-Solano M, Liu Q, Sage J, Weaver AM.
    Proteomics. 2023 Nov 5:e2300030.

30. Gastric coinfection with thiopeptide-positive Cutibacterium acnes decreases FOXM1 and pro-inflammatory biomarker expression in a murine model of Helicobacter pylori-induced gastric cancer

    Lunger C, Shen Z, Holcombe H, Mannion AJ, Dzink-Fox J, Kurnick S, Feng Y, Muthupalani S, Carrasco SE, Wilson KT, Peek RM, Piazuelo MB, Morgan DR, Armijo AL, Mammoliti M, Wang TC, Fox JG.
    Microbiol Spectr. 2023 Nov 28:e0345023.