Vanderbilt University | School of Medicine – Basic Science

“The Reading List” in dark teal with a drawing, in gold tones, of a person with long hair, sitting cross legged and reading a book.

First authors listed in red, only Vanderbilt collaborators are listed except for first authors.

Week of March 20

Recently published

Bridging rapid and sustained antidepressant effects of ketamine. Trends in Molecular Medicine.
Ji-Woon Kim, Kanzo Suzuki, Ege Kavalali, Lisa Monteggia.
Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity. Cancers.
Sarah Groves, Darren Tyson, Vito Quaranta.
Multishot tomography for high-resolution in situ subtomogram averaging. Journal of Structural Biology.
Sagar Khavnekar (Max Planck Institute of Biochemistry), William Wan.
Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. eLife.
Hirohide Takahashi, Toshiki Yamada, Jerod Denton, Kevin Strange, Erkan Karakas.

Preprints

Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors. bioRxiv.
Cody Heiser, Alan Simmons, Frank Revetta, Eliot McKinley, Marisol Ramirez-Solano, Jiawei Wang, Justin Shao, Gregory Ayers, Yu Wang, Sarah Glass, Harsimran Kaur, Andrea Rolong, Bob Chen, Paige Vega, Nabil Saleh, Simon Vandekar, Angela Jones, Kay Washington, Joseph Roland, Qi Liu, Martha Shrubsole, Robert Coffey, Ken Lau.

“Our latest preprint constructs phylogeographic maps of tumor evolution, tracking clonal and [microenvironmental] changes along progression pseudotime,” Ken Lau.
A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α–primase. bioRxiv.
Elwood Mullins, Lauren Salay, Walter Chazin, Brandt Eichman.

“How is an RNA primer transferred to pol alpha for DNA extension? Why are RNA primers 7-10 nucleotides in length? Why are the final RNA-DNA primers 30 nucleotides? Our latest structures provide answers,” Brandt Eichman

Highlighted across the web

Using a semi-automated approach to quantify Unidentified Bright Objects in Neurofibromatosis type 1 and linkages to cognitive and academic outcomes. Magnetic Resonance Imaging.
Emily Harriott, Tin Nguyen, Bennett Landman, Laura Barquero, Laurie Cutting.
Highlighted in Vanderbilt University's Research News.
De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochrome c in cells. Proceedings of the National Academy of Sciences.
Florencia Tomasina (Universidad de la República, Montevideo), Robert Carnahan, Matt Goff, Tracy Cooper, W. Hayes McDonald.
Highlighted in the VUMC Reporter.

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Vanderbilt University School of Medicine Basic Sciences
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