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Implementation of New Initiatives and Policies NIH Applications and Peer Review in 2025
Funding Opportunities by Agency

2025 R Accelerated Grant $200,000/year for up to 4 years.  Applications Due: 06/05/25
2025 ‘A’ Award Grant  $200,000/year for up to 4 years.  Applications Due: 06/16/25

The Colorectal Cancer Alliance (the Alliance) is pleased to announce a Request for Proposals (RFP) for preclinical, translational and clinical research with the potential for high impact on treatment and survivorship of colorectal cancer.  There are no application deadlines. 
Applications will be accepted on a rolling basis.
Young Investigator Accelerator Award Up to $100,000/year for two years.
Senior Investigator Accelerator Award Up to 250,000/year for two years. 
Pilot Accelerator Award Up to $100,000/year for two years. 
Team Science Accelerator Award Up to 250,000/year for two years. 

Discovery Boost Grants (DBG) high-risk, high-reward exploratory cancer research.  Awards are for up to 2 years with $135,000 a year for direct costs, plus 10% allowable indirect costs.  Due: 06/01/25
Mission Boost Grants (MBG)  Stage I Mission Boost: $135,000/year direct cost for two years, plus 10% indirect costs.  Stage II Mission Boost:  Applicants may propose up to 18 months and $545,000 for direct costs, plus 10% indirect costs. Due: 06/01/25
Research Scholar Grants  Awards are for up to 4 years with up to $215,000/year for direct costs, plus 10% allowable indirect costs. Due: 06/01/25
Postdoctoral Fellowship  $66,000 Yr 1, $68,000 Yr 2,  $70,0000 Yr 3, and additional $4,000/year Fellowship allowance. Due: 06/01/25
Clinician Scientist Development Grant (CSDG)  Awards may be for 3 to 5 years with $135,000 a year for direct costs, plus 8% allowable indirect costs. Due: 06/01/25
Damon Runyon-Rachleff Innovation Award Stage 1 Application Guidelines Stage 1: $200,000/year for two years with the opportunity for up to two additional years of funding.  Applications due by 07/01/25
Damon Runyon Fellowship Award  Stipend: $70,000 Yr 1, $72,000 Yr 2, $74,000, Yr 3, and $76,000 Yr 4 plus 2K/year expense allowance. The Damon Runyon Cancer Research Foundation will retire up to $100,000 of any qualifying medical school debt still owed by the awardee.  Applications due by 08/15/25         
Damon Runyon-St. Jude Pediatric Cancer Research Fellowship Award Stipend: $70,000 Yr 1, $72,000 Yr 2, $74,000, Yr 3, and $76,000, Yr 4 plus 2K/year expense allowance.  The Damon Runyon will retire up to $100,000 of any qualifying medical school debt still owed by the Fellow. Applications due: 08/15/25                             
NOT-OD-23-032 Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards Up to 70K.  Deadlines vary by awarding IC.
PAR-23-024 Catalyst Award for Early-Stage Investigators (ESIs) Pursuing Research on HIV Comorbidities, Coinfections, and Complications (DP1- Clinical Trial Optional)  Direct costs are limited to $350,000 per year.  Due: 05/01/25
PAR-24-075 Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Application budgets are not limited but need to reflect the actual needs of the proposed project.  Next due date:05/28/25
PAR-25-082 Co-infection and Cancer (R01 Clinical Trial Not Allowed)   Application budgets are not limited but need to reflect the actual needs of the proposed project.  New applications due: 06/05/25 and 10/05/25.
PAR-23-145 Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)   up to $250,000 direct costs/year.  Due: 08/03/25
PA-24-194 NIH Pathway to Independence Award (Parent K99/R00 – Independent Clinical Trial Not Allowed)  Salary and research costs may be requested to the level provided by the awarding Institute or Center plus indirects.  Due: 06/12/25
PAR-25-083 Co-infection and Cancer (R21 Clinical Trial Not Allowed) The combined budget for direct costs for the two-year project period may not exceed $275,000  Next due dates: 06/16/25 and 10/16/25.
Vanderbilt-Ingram Cancer Center regularly solicits applications for pilot funding to support basic, translational, clinical or collaborative cancer research. Pilot funds allow investigators to collect preliminary data to support an application for independent research support through extramural, peer-reviewed funding. All pilot project awards are funded for one-year periods. For more information, contact us at viccresearchenterprise@vumc.org
NIH Standard  Deadlines
May
AIDS AND AIDS-Related Applications. (New, 
Renewal, Resubmission, Revision) Routing: 04/25/25, Sponsor: 05/07/25
P Series (New, Renewal, Resubmission, Revision) Routing: 05/14/25, Sponsor: 05/25/25 
 
R18, U18, R25 (New, Renewal, Resubmission, Revision) Routing: 05/14/25, Sponsor: 05/25/25

T & D Series (New, Renewal, Resubmission, Revision)  Routing: 05/14/25, Sponsor: 05/25/25
C06/UC6
(New, Renewal, Resubmission, Revision) Routing: 05/14/25, Sponsor: 05/25/25
June
R01 (New)  Routing: 05/23/25, Sponsor: 06/05/25
U01 (New) Routing: 05/23/25, Sponsor: 06/05/25
K Series (New) Routing: 06/02/25, Sponsor: 06/12/25 
R21 (New) Routing: 06/04/25, Sponsor: 06/16/25 
July  
R01 (Renewal, Resubmission, Revision) Routing: 06/25/25, Sponsor: 07/05/25
U01 (Renewal, Resubmission, Revision) Routing: 06/25/25, Sponsor: 07/05/25
K Series (New) Routing: 07/02/25, Sponsor: 07/12/25
R21 (New) Routing: 07/03/25, Sponsor: 07/16/25
August
F series (New, Renewal, Resubmission)  Routing: 07/29/25, Sponsor: 08/08/25
R13, U13 (New, Renewal, Resubmission, Revision) Routing: 07/31/25, Sponsor: 08/12/25
Additional Funding Opportunities:
ChadTough Defeat DIPG Fellowship Grant $100,000/year for postdoctoral fellows.  Applications due: 09/08/25. 
Mathers Foundation Total budget for all three years $600,000 - $700,000  Questions?  Email support@mathersfoundation.org. Nominations due: 09/19/2025.
Additional information is available via the following links:
 CRC-Webinar Recording    
 Town Hall Recording
Missing PMCIDs and other common errors on proposals 
The PMI grants team encourages applicants to review these items often overlooked for compliance on NIH proposals. View...

Planning a proposal submission in the next 2 - 3 months?

In an effort to better serve you, the PMI grants team requests that PIs and Fellows notify us as far in advance as possible of submission plans.  This ensures ample time to complete departmental requirements and also route to OSP for review by their deadline.  Here is the link to the new SRS intake tool for new/resubmission requests: View...
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