The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
Week of January 20
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By Basic Sciences department Biochemistry- Anti-Mycobacterial Activity of Bacterial Topoisomerase Inhibitors with Dioxygenated Linkers. ACS Infectious Diseases.
Mark Mitton-Fry* (The Ohio State University), Jillian Armenia, Jo Ann Byl, Alexandria Oviatt, Neil Osheroff.
- Liver fatty acid binding protein FABP1 transfers substrates to cytochrome P450 4A11 for catalysis. Journal of Biological Chemistry.
Kevin McCarty*, F. Peter Guengerich*.
Supported by the Mass Spectrometry Research Center.
- Highly multiplexed imaging reveals prognostic immune and stromal spatial biomarkers in breast cancer. JCI Insight.
Jennifer Eng* (Oregon Health and Science University), Paula Gonzalez-Ericsson, Melinda Sanders, Bapsi Chakravarthy, Jennifer Pietenpol.
- Conditional requirement for dimerization of the membrane-binding module for BTK signaling in lymphocyte cell lines. Science Signaling.
Timothy Eisen*, Chien-Lun Hung, John Kuriyan*.
Molecular Physiology and Biophysics- E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic β cells. Genes & Development.
Alexis Oguh* (University of Pennsylvania), Shristi Shrestha, Jean-Philippe Cartailler, Rafael Arrojo e Drigo.
Supported by Creative Data Solutions.
- Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic bile duct formation. Development.
Linh Trinh*, Ryan Finnel*, Anna Osipovich, Jessica Musselman, Leesa Sampson, Christopher Wright, Mark Magnuson*.
Supported by Creative Data Solutions, the Vanderbilt Genome Editing Resource, VANTAGE, and the Cell Imaging Shared Resource.
Pharmacology- The pathobiology of neurovascular aging. Neuron.
Monica Santisteban*.
- Structural determinants of peanut induced anaphylaxis. Journal of Allergy and Clinical Immunology.
Scott Smith*, Rebecca Shrem, Bruno Lança, Jian Zhang, R. Stokes Peebles Jr., Benjamin Spiller*.
- Antigenic determinants underlying IgE-mediated anaphylaxis to peanut. Journal of Allergy and Clinical Immunology.
Scott Smith*, Yasmin Khan, Rebecca Shrem, Jonathan Hemler, Joshua Doyle, Jacob Daniel, Jian Zhang, R. Stokes Peebles Jr., Benjamin Spiller.
- Dopamine D1 receptor activation in the striatum is sufficient to drive reinforcement of anteceding cortical patterns. Neuron.
Nuria Vendrell-Llopis* (University of California, Berkeley), Samantha Boggiano, Prashant Donthamsetti.
- Discovery of VU6024578/BI02982816: An mGlu1 Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models. Journal of Medicinal Chemistry.
Carson Reed*, Jacob Kalbfleisch, Jeremy Turkett, Trevor Trombley, Anthony Nastase, Paul Spearing, Daniel Haymer, Mohammad Sarwar, Marc Quitalig, Jonathan Dickerson, Annie Blobaum, Olivier Boutaud, Hyekyung Cho, Colleen Niswender, Jerri Rook, Jeffrey Conn, Bruce Melancon, Craig Lindsley*.
School of Medicine Basic Sciences: Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
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First or corresponding authors are identified with a *. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.
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