June 2024

Let’s ride! Join us for the Cure the Cycle fundraiser. The event will occur on Saturday, October 5, in Napa Valley. There will be both in-person and virtual opportunities to take part. More information is coming soon!

A new study from the Urea Cycle Disorders Consortium (UCDC), NUCDF’s research partner, shows that female OTC carriers face both symptoms and health risks at higher levels than previously thought. 

“We know that these individuals are not truly asymptomatic,” says Jirair K. Bedoyan, M.D., Ph.D. of the University of Pittsburgh, lead author of the study. “Stress, surgery, illness, or metabolic decompensation can tip them over into a hyperammonemia crisis. Symptoms can change over time. Chronically elevated ammonia levels can cause more subtle problems. We need better ways to monitor and manage these risks.”

Read more about the study by clicking below.

For people living with arginase deficiency, a condition without an effective treatment, it is good news that a new therapy that offers dramatic improvement for patients with the condition has been approved for use in Europe and is currently following the process for approval in the U.S.

There are many ways to get involved with NUCDF: