This collection was developed by Dr. Stéphane Verguet at the Center for Health Decision Science. The Disease Control Priorities-Ethiopia (DCP-E) project, sponsored by the Bill & Melinda Gates Foundation, brings evidence and methods of priority setting and health economics closer to policy decision-making in Ethiopia.
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CHDS seminars feature national and international decision science experts. The seminars are virtual via Zoom and require pre-registration using the links provided below.
Speakers share their own perspectives; they do not speak for the Center for Health Decision Science or for Harvard University.
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On Biases and Heterogeneity in Value of Information Analysis using Individual-Level Models
Tuesday, April 16, 1:00 pm ET
This seminar describes how to account for both heterogeneity and biases in economic evaluations using discrete-event simulation (modeling) techniques and quantify the opportunity cost of study biases stemming from non-rigorous or poorly transferable research.
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Joint Modeling of Disability- and Quality-Adjusted Life Year Outcomes
Tuesday, May 7, 1:00 pm ET
This study outlines a methodological framework for joint modeling of Disability- and Quality-Adjusted Life Year outcomes in common decision modeling frameworks. Our primary focus is on how transition matrices and state occupancy payoffs in discrete-time Markov cohort models can be structured to calculate years of life lost to disability (YLD) and years of life lost to premature death (YLL), in addition to quality-adjusted life year (QALY) outcomes. We also demonstrate how our modeling framework extends directly to microsimulation and (in part) to continuous time discrete event simulation (DES) models. In a tutorial application, we use this joint modeling framework to construct a discrete-time Markov cohort natural history model for cardiovascular disease that estimates DALY and QALY outcomes for any country, region, or setting represented in the 2020 Global Burden of Disease data.
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CHDS Publications - Selected Recent
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Bhatt AS, Vaduganathan M, Claggett BL, Kulac IJ, Anand IS, Desai AS, Fang JC, Hernandez AF, Jhund PS, Kosiborod MN, Sabatine MS, Shah SJ, Vardeny O, McMurray JJV, Solomon SD, Gaziano TA. Cost Effectiveness of Dapagliflozin for Heart Failure Across the Spectrum of Ejection Fraction: An Economic Evaluation Based on Pooled, Individual Participant Data from the DELIVER and DAPA-HF Trials. J Am Heart Assoc. 2024 Mar 5;13(5):e032279. PMID: 38390793.
Ekramnia M, Li Y, Haddad MB, Marks SM, Kammerer JS, Swartwood NA, Cohen T, Miller JW, Horsburgh CR, Salomon JA, Menzies NA. Estimated Rates of Progression to Tuberculosis Disease for Persons Infected with Mycobacterium Tuberculosis in the United States. Epidemiology. 2024 Mar 1;35(2):164-173. PMID: 38290139.
Henry E, Al-Janabi H, Brouwer W, Cullinan J, Engel L, Griffin S, Hulme C, Kingkaew P, Lloyd A, Payakachat N, Pennington B, Peña-Longobardo LM, Prosser LA, Shah K, Ungar WJ, Wilkinson T, Wittenberg E. Recommendations for Emerging Good Practice and Future Research in Relation to Family and Caregiver Health Spillovers in Health Economic Evaluations: A Report of the SHEER Task Force. Pharmacoeconomics. 2024 Mar;42(3):343-362. PMID: 38041698.
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CHDS’s Jane Kim is recipient of the Marianne Wessling-Resnick Memorial Mentoring Award in recognition of her mentoring of researchers and faculty at the Harvard Chan School.
Vaccine hesitancy is affected by many factors, including individuals’ willingness to trade-off harms and improvements likely to occur now versus in the future. Arthur Attema explored these time preferences in a CHDS seminar.
Sue J. Goldie, CHDS Faculty Director and the Roger Irving Lee Professor of Public Health, kicked off the global health track at the 16th Annual Congress of the Pulmonary Vascular Research Institute (PVRI) with a keynote address.
CHDS faculty Davene Wright has been awarded NIH funding to evaluate financial incentive programs designed to help adolescents with type-1 diabetes adhere to self-management of their glucose levels.
The Family Well-being Research Network (FAMNET) a collaborative project of CHDS faculty Eve Wittenberg, affiliated faculty Lisa Prosser at the University of Michigan, and Janel Hanmer at the University of Pittsburgh, announces the launch of two on-line Instrument repositories.
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