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The Reading List: The latest biomedical research from Vanderbilt’s SOMBS

The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.

As a researcher affiliated with Vanderbilt University, you should never pay for a scholarly journal article. Vanderbilt’s system of libraries offers several tools that can be helpful when accessing library resources on the open web.

Nitro-arachidonic acid inhibits prostaglandin endoperoxide H synthase 2 through histidine-mediated heme-binding conformational perturbation. Archives of Biochemistry and Biophysics.
Irene Wood* (Universidad de la República), Michael Goodman, Lawrence Marnett.

PEX11β controls early neural progenitor fate through regulation of peroxisomal fission and lipid metabolism. Stem Cell Reports.
Caroline Bodnya*, Rensu Theart, Madeline Colley, Jeffrey Spraggins, Vivian Gama*.

Supported by the Cell Imaging Shared Resource and the Mass Spectrometry Core Lab in the Mass Spectrometry Research Center.
Cryo-electron tomography of functionally validated synapses in human induced neurons.
Aiden Houcek*, Rong Sun*, Spencer Rothfuss, Oliver Chalkley, Ege Kavalali*, Qiangjun Zhou*.

Supported by the Cryo-EM Facility.
Wound-induced syncytia outpace mononucleate neighbors during Drosophila wound repair. eLife.
James White*, Junmin Hua, Jasmine Su, Kaden Tro, Elizabeth Ruark, M. Shane Hutson*, Andrea Page-McCaw*.
Velociraptor Machine Learning Quantifies Similarity to Known Cell Types and Matches Cells Across Flow and Imaging Cytometry Platforms. Cytometry Part A.
Claire Cross*, Rebecca Ihrie, Jonathan Irish*.
Quantifying the Efficacy of Deep Learning-Driven Deformable Registration in Multiplexed-Immunofluorescence Imaging for Nucleus Subtype Classification. Machine Learning for Biomedical Imaging.
Gaurav Rudravaram*, Shunxing Bao, Lucas Remedios, Aravind Krishnan, Michael Kim, Yihao Liu, Chenyu Gao, Rendong Zhang, Bohan Jiang, Qi Liu, Ken Lau, Joseph Roland, M. Kay Washington, Lori Coburn, Keith Wilson, Yuankai Huo, Bennett Landman.
Optimized Sodium-Enhanced MALDI-2 Enables Multimodal Imaging of Triacylglycerols. Journal of the American Society for Mass Spectrometry.
Kameron Molloy*, Cody Marshall, Martin Dufresne, Lukasz Migas, Matthew Schrag, Raf Van de Plas, Jeffrey Spraggins*.

Conserved C-terminal residues adjacent to the canonical PDX1 homeodomain are required for chromatin occupancy and pancreas development.
Anthony Wokasch*, Tianqi Wu, Jennifer Fuhr, Anna Gilbert, Thomas Mehaffey, Carter Barnes, Hassane Mchaourab, Maureen Gannon*.

Supported by the Cell Imaging Shared Resource.
State-dependent inhibition of LRRC8 volume-regulated anion channels by DCPIB. Journal of General Physiology.
Toshiki Yamada*, Erkan Karakas, Jerod Denton*.

Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies. Cell Reports Methods.
Sabina Leonard*, Perry Wasdin, Katherine Webb, Parastoo Amlashi, Jeffrey Rathmell, Benjamin Spiller, Brian Wadzinski, James Crowe, Ivelin Georgiev*.
Drug repurposing identifies candidate uterus-selective tocolytics for preterm labor. Science Translational Medicine.
Shajila Siricilla*, Christopher Hansen, Jeremy Staub, Jordan Walker, Alexus Brown, Sydney Cole, Debasmita De, Lauren Hatcher, Carolyn Simpson, Jackson Rogers, Naoko Boatwright, Stacey Crockett, Deanna Sekulich, Christian Meyer, Vito Quaranta, Quanhu Sheng, John Benjamin, J. M. Newton, Bibhash Paria, Jeff Reese, Jennifer Herington*.

Supported by the High-Throughput Screening Facility.
The 18th World Congress on Polyphenols Applications 2025 and Beyond: Recent Advanced in the Field. Molecular Nutrition & Food Research.
Claus Schneider*.

First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.

Proofig AI is your go-to platform for catching image issues like duplications, manipulations, plagiarism, and AI-generated problems. This resource is provided at no cost to primary SOMBS faculty and is part of our commitment to supporting research excellence and maintaining the highest standards of scientific integrity. Faculty can access Proofig by visiting its homepage or their OneVU dashboard.

Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter. Please send the paper’s URL.

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