The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
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Department of Biochemistry |
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Gyrase and Topoisomerase IV as Antibacterial Targets for Gepotidacin and Zoliflodacin: Teaching Old Enzymes New Tricks. International Journal of Molecular Sciences.
Neil Osheroff*. - Protocols to evaluate mutant specificity of an oncogene-targeting siRNA using orthogonal in vitro and in vivo approaches. STAR Protocols.
Lyla Stanland* (EnFuego Therapeutics Inc.), Martin Egli. - New targets and procedures for validating the valence geometry of nucleic acid structures. Nucleic Acids Research.
Jiří Černý* (Czech Academy of Sciences), Martin Egli*. - Discovery of Fragment-Based Inhibitors of SARS-CoV-2 PLPro. Journal of Medicinal Chemistry.
Qiangqiang Wei*, Ashley Taylor, Mahesh Angadrao Barmade, Kevin Teuscher, Somanath Chowdhury, Chideraa Apakama, Jordan Anderson-Daniels, Tyson Rietz, Taylor South, Mackenzie Crow, Bin Zhao, Kangsa Amporndanai, John Sensintaffar, Jason Phan, Mark Denison, Taekyu Lee, Stephen Fesik*.
Supported by the Biomolecular NMR Facility and the High-Throughput Screening Facility.
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Department of Cell and Developmental Biology |
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Paracrine Hormonal Signals From Islet α-Cells Regulate Microtubule Dynamics in β-Cells to Promote Insulin Secretion in Mouse and Human Islets. Diabetes.
Kung-Hsien Ho*, Syed Barmaver*, Shannon Gibson, Ruiying Hu, Mahircan Yagan, Hamida Ahmed, David Jacobson, Irina Kaverina*, Guoqiang Gu*.
Selected as Paper of the Month by the journal. -
Secreted exosomes induce filopodia formation. eLife.
Caitlin McAtee*, Mikin Patel*, Daisuke Hoshino* (Kanagawa Cancer Center), Bong Hwan Sung, Ariana von Lersner, Mingjian Shi, Nan Hyung Hong, Anna Young, Evan Krystofiak, Andries Zijlstra, Alissa Weaver*.
Supported by the Cell Imaging Shared Resource.
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Department of Molecular Physiology and Biophysics |
Department of Pharmacology |
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Intranasal cocaine self-administration in male mice. Nature Communications.
Kirsty Erickson*, Yizhen Quan, Zahra Farahbakhsh, Hannah Branthwaite, Keaton Song, Justin Kim, Janice Lee, Katherine Gibson-Corley, Cody Siciliano*.
School of Medicine Basic Sciences: A more realistic way to study cocaine use could accelerate addiction research -
RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b+ Bregs thereby overcoming melanoma PD1-resistance. Nature Communications.
Chi Yan*, Weifeng Luo, Jinming Yang, Jing Yang, Sheau-Chiann Chen, Kensey Bergdorf, Qianni Hu, Vivian Weiss, Douglas Johnson, Qi Liu, Ann Richmond*. -
Discovery of VU6083859, a TAOK1 Selective Inhibitor, and VU6080195, a pan-TAOK Activator. ACS Chemical Neuroscience.
Daniel Schultz*, Lauren Parr, Hunter Sweet, Sean Lamb, Julie Engers, Nathaniel Napier, Hallie McKinnie, David Whomble, Valerie Kramlinger, Olivier Boutaud, Craig Lindsley*.
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First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
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Faculty resource: Proofig AI |
Proofig AI is your go-to platform for catching image issues like duplications, manipulations, plagiarism, and AI-generated problems. This resource is provided at no cost to primary SOMBS faculty and is part of our commitment to supporting research excellence and maintaining the highest standards of scientific integrity. Faculty can access Proofig by visiting its homepage or their OneVU dashboard.
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Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter. Please send the paper’s URL.
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Vanderbilt University School of Medicine Basic Sciences
MRB III U-B1200, 465 21st Avenue South
Nashville, TN 37240
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