The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
|
|
|
Department of Biochemistry |
-
Synthesis and Characterization of Aminooxy Click Chemistry-Mediated Bis-Conjugates of siRNAs and Evaluation of Their RNAi Activity. Bioconjugate Chemistry.
Dhrubajyoti Datta* (Alnylam Pharmaceuticals), Mark Neil Tolentino* (Alnylam Pharmaceuticals), Martin Egli. -
Acute degron-mediated RUNX1 loss reprograms enhancer activity associated with epithelial destabilization and initiation of cancer hallmarks. Cell Reports.
Andrew Fritz* (University of Vermont), Kristy Stengel, Scott Hiebert. -
Classification models for KCNQ1 variants distinguish functional and trafficking effects to enhance pathogenicity interpretation. Proceedings of the National Academy of Sciences.
Ana Chang-Gonzalez*, Eric Bell, Kathryn Butcher, James Scott, Charles Sanders, Kaitlyn Ledwitch, Jens Meiler*.
Center for Structural Biology: Machine learning reveals how genetic variants disrupt a cardiac ion channel
|
Department of Cell and Developmental Biology |
- Multimodal Imaging of the Cellular and Extracellular Microenvironment on the Same Formalin-Fixed Paraffin-Embedded Tissue Section (preprint). bioRxiv.
Jade Macdonald*, Thai Pham, Alan Simmons, Harsimran Kaur, Jamie Allen, Anna Smith, Audra Judd, Seung Woo Kang, Madeline Colley, Melissa Farrow, Ken Lau, Jeffrey Spraggins*.
|
Department of Molecular Physiology and Biophysics |
-
Overnutrition in mice impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations. The Journal of Clinical Investigation.
Jessica Rampy*, Alejandra Paola Torres-Manzo, Kendra Hoffsmith, Matthew Loberg, Quanhu Sheng, Rafael Arrojo e Drigo, Huiying Wang, Vivian Weiss, Nancy Carrasco*.
Supported by the Cell Imaging Shared Resource, Creative Data Solutions, and the Vanderbilt Mouse Metabolic Phenotyping Center.
School of Medicine Basic Sciences: Chicken or the egg: New study suggests overeating could lead to hypothyroidism -
Electronic Health Record-Based Phenotyping for Obsessive-Compulsive Disorder: Algorithm Development and Multicenter Validation Study. JMIR Mental Health.
Bo Wang* (Massachusetts General Hospital), Tyne Miller-Fleming, Donald Hucks, Emily Gantz, Rebecca Johnston, Angela Maxwell-Horn, Nancy Cox, James Sutcliffe, Evonne McArthur, Lea Davis*.
|
Department of Pharmacology |
|
|
First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
|
|
|
Faculty resource: Proofig AI |
Proofig AI is your go-to platform for catching image issues like duplications, manipulations, plagiarism, and AI-generated problems. This resource is provided at no cost to primary SOMBS faculty and is part of our commitment to supporting research excellence and maintaining the highest standards of scientific integrity. Faculty can access Proofig by visiting its homepage or their OneVU dashboard.
|
|
|
Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter. Please send the paper’s URL.
|
Tell us before you publish
We’re really excited to promote your papers—help us by letting us know if your paper has been accepted or recently published.Yes, you can share your embargoed manuscript with the comms team!
Please fill out this form and tell us about your paper and its impact.
Pro-tip: Bookmark this page on your browser for easy access.
|
|
|
|
Vanderbilt University School of Medicine Basic Sciences
MRB III U-1200 465 21st Avenue South | Nashville, TN 37240 US
|
|
|
|
|
