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  Issue 24  •  July 2024                                                                                  PMI Grants Team
Changes Coming to NIH Applications and Peer Review in 2025         
These changes include updates to the peer review and submission of most research project grants, fellowships, and training grants; common forms for NIH biographical sketch and current and pending (other) support; updated instructions for reference letters; and the transition to FORMS-I application instructions. Although each of these initiatives has specific goals, they are all meant to simplify, clarify, and/or promote greater fairness towards a level playing field for applicants throughout the application and review process.  
Key changes                                                 
  • Simplified review framework for most research project grants
  • Improvements to the NRSA fellowship application and review process  
  • Updates to reference letter guidance 
  • Updates to NRSA training grant applications 
  • Updated application forms (FORMS-I) 
  • Common forms for biographical sketch and current and pending (Other) support 
Tips for applicants
  • Verify whether the activity code for your target funding opportunity is impacted and identify your target due date. 
  • If your activity code is impacted by the new framework and your target due date is on or after January 25, 2025, pay extra attention to the opportunity you use to apply.

Links with additional details regarding proposed changes
Foreign Talent Recruitment Programs
Vanderbilt University Medical Center (VUMC) is committed to fostering a collaborative learning environment of open scientific research, the intellectual exchange of ideas, and international academic research collaborations and engagement. VUMC is also committed to ensuring the security of this research, in partnership with federal research agencies. 
There are three major categories of international research activities: 

1.) International Collaboration
2.) Foreign Talent Recruitment Programs
3.) Malign Foreign Talent Recruitment Programs

These categories are defined by the CHIPS and Science Act and resulting Office of Science and Technology Policy (OSTP) policy guidance to help guide federal research agencies in drafting and implementing their individual policies. More details available here: vumc.org/oor/FTRPs
NIAID Financial Management Plan
Competing investigator-initiated awards will be funded at 90 percent of approved funding level with start dates reset by one month. This excludes fellowship (F), training (T), career development (K), and small business (SBIR/STTR) awards, and awards funded with non-direct appropriations (e.g., emergency supplemental COVID appropriations), which will be funded with no reduction to the approved funding level. NIAID
NCI Funding Policy
NCI will generally fund both categorical and SNAP non-competing grants at 95% of the committed level. This policy applies to all grants, with the exception of the NRSAs, Career, Cancer Education, Continuing Education, P30 Cancer Centers, Conference, AIDS related grants, International Research Training Grants, Small Grants, Research Specialist, Pathway to Independence, SBIR, and STTR awards, which will be funded at committed levels. Non-competing grants that were awarded under the continuing resolution policy will be revised accordingly. NCI
NIH Data Management (DMS) & Sharing Plan 
The NIH Data Management & Sharing DMS Policy applies to all research, funded or conducted in whole or in part by NIH, that results in the generation of scientific data.
Under the DMS policy, NIH expects that investigators and institutions:
  • Plan and budget for the managing and sharing of data
  • Submit a DMS plan for review when applying for funding
  • Comply with the approved DMS plan
Additional information is available via the following links:

Planning a proposal submission in the next 2 - 3 months?

In an effort to better serve you, the PMI grants team requests that PIs and Fellows notify us as far in advance as possible of submission plans.  This ensures ample time to complete departmental requirements and also route to OSP for review by their deadline.   
Missing PMCIDs and other common errors on proposals 
The PMI grants team encourages applicants to review these items often overlooked for compliance on NIH proposals.
Just-In-Time (JIT)
When do you need to submit a JIT for NIH and how does it work? Click here for detailed information about NIH's Just-in-Time mechanism and PMI JIT policy. 
Here are a few links for various institutes' current paylines: NIAID, NIDDK, NCI, NHLBI.
Funding Opportunities by Agency
American Cancer Society                                                           
Discovery Boost Grants (DBG) high-risk, high-reward exploratory cancer research.  Awards are for up to 2 years with $135,000 a year for direct costs, plus 10% allowable indirect costs.  Next submission deadlines: 10/15/24 and 04/01/25.
Mission Boost Grants (MBG)  Stage I Mission Boost: $135,000/year for two years direct costs, plus 10% indirect costs.  Stage II Mission Boost:  Applicants may propose up to 18 months and $545,000 for direct costs, plus 10% indirect costs. Next submission deadlines: 10/15/24 and 04/01/25.
Research Scholar Grants  Awards are for up to 4 years with up to $215,000/year for direct costs, plus 10% allowable indirect costs. Next submission deadlines: 10/15/24 and 04/01/25.
Postdoctoral Fellowship  $66,000 Yr 1, $68,000 Yr 2,  $70,0000 Yr 3, and additional $4,000/year Fellowship allowance. Next submission deadlines: 10/15/24 and 04/01/25.
Clinician Scientist Development Grant (CSDG)  Awards may be for 3 to 5 years with $135,000 a year for direct costs, plus 8% allowable indirect costs. Next submission deadlines: 10/15/24 and 04/01/25.                                        

American Heart Association                                                                         
AHA Postdoctoral Fellowship  Annual stipend based on years of experience plus $12,200/year health insurance and $3,000/year in project support. One or two years. May apply for a second two-year award. Application due: 09/05/24
AHA 2025 Merit Award $200,000/year for five years with 10% indirect costs. LOI due 09/10/2024.  Full application by invitation: 11/14/24.
AHA Established Investigator Award  $110,000/year for five years, including 10% indirect costs. LOI due 10/02/24. Full proposal by inviation 01/08/25.  
AHA Collaborative Science Award  Total Award Amount: $1,000,000; indirects 10%  Pre-proposal  due by 10/03/24.  Full application by invitation: 01/09/25          
AHA 2025 Tranformational Project Award $100,000/year for three years, including 10% indirects. Full application: 02/13/25.
2025 Innovative Project Award $100,000/year including 10% indrects for two years.  Pre-proposal due 12/05/24.  Full application by invitation: 03/06/25.

Congressionally Directed Medical Programs                                    
Prostate Cancer Research Program Implementation Science Award  HT942524PCRPISA  $2.0M for the entire period of perfomance (maximum 4 years).  Pre-application due 08/09/24.   Full application by invitation due 08/30/24.
Prostate Cancer Research Program Early Investigator Research Award  HT942524PCRPEIRA  $300,000 for the entire period of perfomance (maximum 2 years).  Pre-application due 08/09/24.   Full application by invitation due 08/30/24.
Toxic Exposures Research Program Translational Research Award  HT942524TERPTRA  $800,000 for the Single PI Option and $1,600,000 (combined direct costs) for the Partnering PI Option for the entire period of performance (maximum 3 years).  Pre-application due 08/13/24.   Full application by invitation due 11/07/24.
Toxic Exposures Research Program Investigator-Initiated Research Award HT942524TERPIIRA  $500,000 for the entire period of perfomance (maximum 3 years). Pre-application due 08/13/24.   Full application by invitation due 11/07/24.

Crohn's & Colitis Foundation                                                                
Senior Research Awards  up to $118,182 per year, 10% indirect costs.  Duration of award is one to three years. LOI: 11/15/24.  Full application: 01/24/25.
Litwin IBD Pioneers $130,000 including 10% indirects for clinical trials; and up to $110,000 including 10% indirects for lab-based studies.   Up to two years LOI: 11/15/24.  Full application: 01/24/25.
Career Development Awards Award salary will match applicants’ institutional salary (salaries may be supplemented by the applicant’s institution), depending on postgraduate year (PGY) level, up to $60,000 per year and fringe - up to $15,000 per year, plus $27,500 for non-salary/fringe expenses. LOI: 11/15/24.  Full application: 01/24/25.
Research Fellowship Awards  Maximum award per year: $70,000 for one to three years including salary, fringe, and non-salary/fringe expenses. LOI: 11/15/24.  Full application: 01/24/25.

Damon Runyon Cancer Research Foundation                                     
Damon Runyon Physician-Scientist Training Award  Award period is four years, total award: $460,000.  Additionally, The Damon Runyon Cancer Research Foundation will retire up to $100,000 of any qualifying medical school debt still owed by the awardee. Applications due by 12/02/24.
Damon Runyon Quantitative Biology Fellowship Award Stipend: $76,000 Yr 1, $78,000 Yr 2,  and $80,000 Yr 3 plus 2K/year expense allowance. Applications due by 12/02/24.

Damon Runyon Clinical Investigator Award $200,000/year for three years. The Damon Runyon Cancer Research Foundation will retire up to $100,000 of any qualifying medical school debt still owed by the awardee. Applications due by 02/03/25.

Damon Runyon Fellowship Award  Stipend: $70,000 Yr 1, $72,000 Yr 2, $74,000, Yr 3, and $76,000 Yr 4 plus 2K/year expense allowance. The Damon Runyon Cancer Research Foundation will retire up to $100,000 of any qualifying medical school debt still owed by the awardee.  Applications due by 03/15/25


NIH Director's Awards                                                          
NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional) RFA-RM-24-003  $1.5 million direct costs for 5 years. Single PI only and must be an early stage investigator.  Application due 08/19/24.

NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-24-004  Application budgets are not limited but must be commensurate with the scope of the proposed research.  Due by 09/03/24.

NIH Director’s Early Independence Awards (DP5 Clinical Trial Optional)  RFA-RM-24-005  up to $250,000 in direct costs per year plus indirect costs. LOI due 08/06/24; full application 09/06/24.

NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional) RFA-RM-002 up to $700,000 in direct costs per year plus indirect costs.  Full application due by 09/09/24.

                                                                                                                                
Patient-Centered Outcomes Research Institute (PCORI)

  • Category 1 will support research projects with direct costs up to and  including $5 million.
  • Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $10 million. 
  • Category 3 will support research projects with direct costs up to $10 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. 
Funding awards under this PFA are expected to be announced in November 2024.  
NIH Standard Deadlines
September
AIDS AND AIDS-Related Applications. (New, Renewal, Resubmission, Revision) Routing: 8/27/24, Sponsor: 09/07/24
P Series (New, Renewal, Resubmission, Revision) Routing: 09/13/24, Sponsor: 09/25/24 

R18U18R25 (New, Renewal, Resubmission, Revision) Routing: 09/13/24, Sponsor: 09/25/24

T & D Series (New, Renewal, Resubmission, Revision)  Routing: 09/13/24, Sponsor: 09/25/24
C06/UC6
(New, Renewal, Resubmission, Revision) Routing: 09/13/24, Sponsor: 09/25/24
October
R01 (New)  Routing: 09/25/24, Sponsor: 10/05/24
U01 (New) Routing: 09/25/24, Sponsor: 10/05/24
K Series (New) Routing: 10/02/24, Sponsor: 10/12/24 
R21 (New) Routing: 10/04/24, Sponsor: 10/16/24 
November  
R01 (Renewal, Resubmission, Revision) Routing: 10/24/24, Sponsor: 11/05/24
U01 (Renewal, Resubmission, Revision) Routing: 10/24/24, Sponsor: 11/05/24
K Series (New) Routing: 10/31/24, Sponsor: 11/12/24 
R21 (New) Routing: 11/05/24, Sponsor: 11/16/24
December
F series (New, Renewal, Resubmission)  Routing: 11/26/24, Sponsor: 12/08/24
R13U13 (New, Renewal, Resubmission, Revision) Routing: 12/02/24, Sponsor: 12/12/24
January
AIDS AND AIDS-Related Applications. (New, 
Renewal, Resubmission, Revision) Routing: 12/27/24, Sponsor: 01/07/25
P Series (New, Renewal, Resubmission, Revision) Routing: 01/14/25, Sponsor: 01/25/25 
 
R18U18R25 (New, Renewal, Resubmission, Revision) Routing: 01/14/25, Sponsor: 01/25/25

T & D Series (New, Renewal, Resubmission, Revision)  Routing: 01/14/25, Sponsor: 01/25/25
C06/UC6
(New, Renewal, Resubmission, Revision) Routing: 01/14/25, Sponsor: 01/25/25
February
R01 (New)  Routing: 01/24/25, Sponsor: 02/05/25
U01 (New) Routing: 01/24/25, Sponsor: 02/05/25
K Series (New) Routing: 01/31/25, Sponsor: 02/12/25 
R21 (New) Routing: 02/04/25, Sponsor: 02/16/25 
Additional Funding Opportunities:
PAR-24-075 Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Application budgets are not limited but need to reflect the actual needs of the proposed project.  Next due dates: 09/26/24 and 01/28/25
PAR-23-275 NIAID and NIDDK Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)  Application budgets are not limited but need to reflect the actual needs of the proposed project.  Next due dates: 10/05/24 and 02/05/25.  Next AIDS deadlines: 09/07/24 and 01/07/25.
PA-24-194 NIH Pathway to Independence Award (Parent K99/R00 – Independent Clinical Trial Not Allowed)  Salary and research costs    may be requested to the level provided by the awarding Institute or Center plus indirects.  Next due dates: 10/12/24 and 02/12/25. 
PAR-24-225 Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)  Salary and research costs    may be requested to the level provided by the awarding Institute or Center plus indirects.  Next due dates: 10/12/24 and 02/12/25. 
PAR-23-056 Co-infection and Cancer (R21 Clinical Trial Not Allowed) The combined budget for direct costs for the two-year project period may not exceed $275,000  Next due dates: 10/16/24 and 02/16/25.
PAR-23-055 Co-infection and Cancer (R01 Clinical Trial Not Allowed)   Application budgets are not limited but need to reflect the actual needs of the proposed project.  Earliest submission dates for new applications: 10/05/24 and 02/05/25.
Request for Nominiations 2025 LUPUS INSIGHT PRIZE Lupus Research Alliance $100,000.   Nominations due 12/20/24.
Jane Coffin Childs Memorial Fund for Medical Research 3 year fellowship: 70K - Yr 1, 72K - Yr 2, and 74K - Yr 3 plus 2K/year research allowance.  Proposals due: 01/31/25.
VUMC Faculty Research Scholars $110,000/year, SOI: 01/16/25, full application 02/15/25.
PAR-24-037 HIV Vaccine Research and Design (HIVRAD) Program (P01 Clinical Trial Not Allowed)   Up to $2,500,000 directs/year. LOI: 30 days prior to application deadline.  Due: 03/13/25.
PAR-23-246 Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed)  Up to  $475,000 in direct costs/year. Next due dates: 11/04/24 and 05/05/25.

Have a pressing inquiry regarding submissions or post-award items? 

We're here to help! Candice Stevens, Associate Director, Lauren Milam, Sr Financial Manager, Edith Ashcraft, Sr Financial Analyst, Doug Smith, Sr Financial Analyst, Leigh Thompson, Budget Accounting Analyst Post-Award, Karin Sack, Grants Manager,  and Alethea Kelly, Grants Manager.
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