Forwarded by the Los Angeles County Department of Public Health
| CDC Health Advisory:
Domestically Acquired Cyclosporiasis Cases in Multiple U.S. States, 2026
July 14, 2026
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The Centers for Disease Control and Prevention (CDC) issued a Health Advisory today notifying clinicians of cases of domestically acquired cyclosporiasis in multiple U.S. states. The advisory includes background information about cyclosporiasis, current U.S. surveillance data, and recommendations for clinicians and laboratorians to support recognition, diagnosis, management and reporting.
To date, Los Angeles County has identified 27 cases this year. All are travel-associated and are not linked to the current domestically acquired multi-state outbreak.
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CDC Recommendations for Clinicians
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Consider cyclosporiasis in patients presenting with prolonged or relapsing watery diarrhea, particularly during the May−August cyclosporiasis season, even without a history of international travel.
- Ask patients with suspected or confirmed cyclosporiasis about their recent food and travel history to assist local investigations.
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Specifically request Cyclospora laboratory testing on stool specimens because routine ova and parasite (O&P) examinations might not reliably detect the parasite. Consider molecular (PCR-based) diagnostic testing where available, because it can improve detection.
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Treat confirmed cases of cyclosporiasis with 7−10 days of trimethoprim-sulfamethoxazole (TMP-SMX) for immunocompetent adults and children over age 2 months; consider longer courses for patients with immunocompromising conditions. Consult current CDC clinical guidance for recommended dosing.
- Advise patients to stay well hydrated, especially if diarrhea is frequent or severe.
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In LA County, providers should report cyclosporiasis infections to Public Health within one working day.
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Los Angeles County DPH Acute Communicable Disease Control:
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- Fax a CMR to 888-397-3778 or 213-482-5508 or send via secure email to RPU@ph.lacounty.gov, or
- Call 888-397-3993 weekdays 8:00 am–4:30 pm.
- For consultation call 213-240-7941 8:00 am-5:00 pm
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You can also copy and paste this link into your browser https://www.cdc.gov/han/php/notices/han00531.html
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To view this and other communications or to sign-up to receive LAHANs, please visit ph.lacounty.gov/lahan.
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