EON Network: January 2025 Newsletter |
The EON Network was established to facilitate communication between exercise oncology and oncology nutrition researchers and clinicians to achieve our joint goal of improving cancer treatment outcomes.
The EON Network monthly newsletter includes upcoming webinars, updates on exercise oncology and oncology nutrition related events, publications that may be of interest, and resources. This information is also available on the EON Network webpage. Past newsletters are archived.
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Register for the Next EON Webinar! |
Thursday, February 20, 2025, 2-3 PM ET |
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Exercise in Older Breast Cancer Survivors: Are There Racial Differences in Exercise Effect on Outcomes? | Cynthia Owusu, MD, MS
Cynthia Owusu, MD, MS will give a presentation reporting on results from the IMPROVE Study, a study of 213 older African American (AA) and Non-Hispanic White (NHW) breast cancer survivors (BCSs) that was funded by the National Institute on Minority Health and Health Disparities. The study demonstrated that combined aerobic and resistance exercise improved physical performance in older BCSs, and that exercise effect might be moderated by race, with AAs appearing to derive larger benefits in comparison with NHWs.
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Highlighted Publication: "Potential benefits from physical exercise in advanced cancer patients undergoing systemic therapy? A narrative review of the randomized clinical trials"
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Bozzetti F. Potential benefits from physical exercise in advanced cancer patients undergoing systemic therapy? A narrative review of the randomized clinical trials. Curr Oncol 2024;31(12):7631-7646. PMID: 39727686
Bozzetti writes: "The aim of this paper (1) was to investigate the potential of physical exercise (PA) as an adjunct to the oncologic medical therapy in cancer patients because there is a wide experience that the constant practice of PA not only can prevent many types of tumours but also that cancer survivors can benefit from it as regards the overall survival and specific cancer-free survival.
"I focused on 3 main endpoints (fat-free mass, muscle function and quality of life) and I only relied on RCTs to minimize interpretative bias.
"The analysis showed that a benefit in quality of life and fat-free mass was reported in 100% and 36% of the studies in malnourished patients, values which were 2 and 3 times higher than in non-malnourished ones, respectively.
"While the message of a potential benefit of PA in these patients appears clear, much uncertainty remains on the best regimen to follow: aerobic or resistance exercise or both, how much and how many times per week, what about the high intensity interval training and privileging eccentric versus concentric muscle activity, how much an optimized nutritional support might potentiate the effects of PA.
"However, the lack of consolidate data on the effects of PA should not deny the cancer patient from receiving this approach which is gaining wide acceptance in the anticancer armamentarium."
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Additional Publications of Interest
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Kempin S, Buchner A, Brose SF, Schmidt-Hegemann N, May M, Wolff I, Kravchuk A, Stief C, Brookman-May SD, Enzinger B. The effect of resistance and/or aerobic training on quality of life, fitness, and body composition in prostate cancer patients-A systematic review and meta-analysis. Cancers (Basel) 2024;16(24):4286. PMID: 39766184
Schouten AEM, Hiensch AE, Frederix GWJ, Monninkhof EM, Schmidt ME, Clauss D, Gunasekara N, Belloso J, Trevaskis M, Rundqvist H, Wiskemann J, Müller J, Sweegers MG, Fremd C, Altena R, Bijlsma RM, Sonke G, Lahuerta A, Mann GB, Francis PA, Richardson G, Malter W, Kufel-Grabowska J, van der Wall E, Aaronson NK, Senkus E, Urruticoechea A, Zopf EM, Bloch W, Stuiver MM, Wengstrom Y, Steindorf K, van der Meulen MP, May AM. Supervised exercise for patients with metastatic breast cancer: A cost-utility analysis alongside the PREFERABLE-EFFECT randomized controlled trial. J Clin Oncol 2025 Jan 13:JCO2401441. Epub ahead of print. PMID: 39805062
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2025 NIH Summer Institute on Behavioral Clinical Trials
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The 2025 NIH Summer Institute on Behavioral Clinical Trials application portal is NOW OPEN! The deadline to submit your application for the 2025 cohort is Friday, January 31, 2025.
The training course consists of a 4-day in-person workshop followed by 9 monthly virtual meetings with small learning communities.
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| NIH/NCI Funding Opportunities |
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