The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
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Department of Biochemistry
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Bacterial type II topoisomerases cleave DNA in a species-specific manner. Nucleic Acids Research.
Ian Morgan* (National Heart, Lung, and Blood Institute), Jeffrey Jian*, Jillian Armenia, Neil Osheroff*. - Distinct repair outcomes from single and convergent replication fork collapse. Nature Structural & Molecular Biology.
Sara Conwell*, Khushi Patel, Savannah Weeks-Pollenz, Steven Dahmen, Matthew Cranford, David Cortez, James Dewar*.
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Department of Cell and Developmental Biology |
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EGFR S442 ectodomain mutation confers cetuximab resistance that can be overcome by ERBB2 blockade with trastuzumab-deruxtecan. Cancer Letters.
Sarah Harmych*, Neeraj Joshi*, Hidenori Tanaka, Galina Bogatcheva, Marisol Ramirez, Ramona Graves-Deal, Claiborne Tydings, Marina Elia, Hunter Lischwe Mueller, Isabella Silvestri, Khaw Ti Ning, Claudia Wahoski, Chelsie Sievers, James Higginbotham, Maria Johnson Irudayam, Frank Revetta, Zhiguo Zhao, Jeffrey Franklin, M Kay Washington, Xingyi Guo, Allison Walker, Jens Meiler, Krishna Mudumbi, Qi Liu, Robert Coffey, Eben Rosenthal, Bhuminder Singh*. -
A role for LIMA1 in the assembly of actin bundle-supported protrusions. Molecular Biology of the Cell.
Jennifer Silverman*, Kianna Robinson, Su Min Hong, Evan Krystofiak, Matthew Tyska*.
Supported by the Cell Imaging Shared Resource.
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Department of Molecular Physiology and Biophysics | -
Heterogeneous endocrine cell composition defines human islet functional phenotypes. Nature Communications.
Carmella Evans-Molina* (Indiana University School of Medicine), Yasminye Pettway*, Diane Saunders*, Seth Sharp* (Stanford School of Medicine), Thomas Bate, Heather Durai, Shaojun Mei, Anastasia Coldren, Corey Davis, Conrad Reihsmann, Alexander Hopkirk, Jay Taylor, Amber Bradley, Radhika Aramandla, Greg Poffenberger, Adel Eskaros, Regina Jenkins, Danni Shi, Ke Xu, Hakmook Kang, Fan Feng, Jean-Philippe Cartailler, Alvin Powers, Marcela Brissova*.
Supported by the Center for Stem Cell Biology.
Vanderbilt Health News: Human islet function, diabetes risk defined by heterogeneous endocrine cell composition -
Aging Remodels Mitochondrial Architecture Across the Male Reproductive Axis (preprint). Research Square.
Suzanna Navarro*, Claude Albritton*, Estevao Scudese* (Federal University of the State of Rio de Janeiro), Calixto Pablo Hernandez Perez, Max Kushner, Andrea Marshall, Jenny Schafer, Bret Mobley, Julia Berry, Annet Kirabo, Celestine Wanjalla, Antentor Hinton Jr.*
Supported by the Cell Imaging Shared Resource. -
Mitochondrial dysfunction in hepatocellular carcinoma: Linking aging hallmarks to organelle dynamics, metabolism, and disease progression. Aging Advances.
Bislom Mweene* (Livingstone Center for Prevention and Translational Science), Kit Neikirk*, Sepiso Masenga*, Andrea Marshall, Amber Crabtree, Claude Albritton, Benjamin Rodriguez, Annet Kirabo, Mohd Mabood Khan*, Antentor Hinton Jr.* -
Aging promotes the mitochondrial contact site and cristae organizing system complex dysfunction in metabolic-associated steatotic liver disease: A narrative review. Aging Advances.
Bislom Mweene* (Livingstone Center for Prevention and Translational Science), Sepiso Masenga*, Kit Neikirk, Andrea Marshall, Ron McMillian, Annet Kirabo, Benjamin Rodriguez, Mohd Mabood Khan*, Antentor Hinton Jr.* -
Application of a Blood-Brain Barrier Organ-on-a-Chip Model for Assessment of Countermeasure Efficiency Against Eastern Equine Encephalitis Virus. Viruses.
Niloufar Boghdeh-Olson* (George Mason University), Clayton Britt, David Schaffer, John Wikswo.
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First or corresponding authors are identified with an *. Only Vanderbilt collaborators are listed except for first authors.
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Faculty resource: Proofig AI
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Proofig AI is your go-to platform for catching image issues like duplications, manipulations, plagiarism, and AI-generated problems. This resource is provided at no cost to primary SOMBS faculty and is part of our commitment to supporting research excellence and maintaining the highest standards of scientific integrity. Faculty can access Proofig by visiting its homepage or their OneVU dashboard.
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Papers must be submitted by email by noon on Thursdays to be included in the following week’s newsletter. Please send the paper’s URL.
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Vanderbilt University School of Medicine Basic Sciences
MRB III U-1200 465 21st Avenue South | Nashville, TN 37240 US
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