EON Network: September 2026 Newsletter |
The EON Network monthly newsletter shares upcoming webinars, updates on exercise oncology and oncology nutrition related events, publications that may be of interest, and resources. This information is also available on the EON Network webpage. Past newsletters are archived.
Opportunities such as training workshops, publication submissions, and funding applications are great to share with the EON Network. We invite all to submit relevant opportunities by emailing eonnetwork@bsc.gwu.edu!
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Wednesday, October 21 | 3:00 - 4:00 PM
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| Diet and Chemotherapy-Induced Peripheral Neuropathy: Emerging Evidence, Future Directions
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Chemotherapy-induced peripheral neuropathy (CIPN) is a significant side effect of certain types of chemotherapies that impacts quality of life and treatment tolerance. Emerging observational evidence has highlighted the relationship between diet and the development and reduction of CIPN. This presentation will discuss this existing body of evidence and the mechanisms by which diet may impact CIPN, particularly CIPN caused by platinum-based chemotherapies. This presentation will also present an upcoming randomized control trial investigating diet to delay CIPN development and explore future directions.
Stephanie L.E. Compton, Ph.D., RD is a Postdoctoral Research Fellow and Registered Dietitian in the Exercise and Cancer Biology Research Program at AdventHealth Translational Research Institute. Her research examines how nutrition and physical activity impact cancer survivors’ cancer treatment tolerance, chronic disease risk, quality of life, and overall survival. Dr. Compton has received grants from the American Cancer Society, American Institute for Cancer Research, and the National Cancer Institute. She is currently supported by a K99/R00 Pathway to Independence Award from the National Cancer Institute, which is investigating the role of diet in the development of chemotherapy-induced peripheral neuropathy.
The CPE activity application for this EON webinar is pending CDR review and approval for 1 CPEU for dietetics professionals.
The George Washington University School of Medicine and Health Sciences is pending approval for this live activity to offer a maximum of 1.00 AMA PRA Category 1 Credit(s)™ for physicians, physician assistants, and nurse practitioners.
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Zwart NR, van Duijnhoven FJ, Wesselink E, Lubberman FJ, Ulrich CM, McKay JA, van Halteren HK, McCann A, Ueland PM, Kampman E, Kok DE. One-carbon metabolism and chemotherapy-induced toxicities in patients with stage II-III colorectal cancer: a prospective cohort study. Am J Clin Nutr 2026;124(3):101457. PMID: 42508575
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"B-vitamins are important for DNA synthesis and repair, a process which is targeted by many forms of chemotherapy. The extent to which B-vitamins are also implied in toxicity profiles of common chemotherapeutic drugs for colorectal cancer (CRC) remain poorly understood. Hence, in this study associations between B-vitamins and chemotherapy-induced toxicities were evaluated among 297 patients with colorectal cancer. Pretreatment plasma concentrations of vitamin B2, B6 and B12, as well as folate were measured, and toxicities were defined as any toxicity-induced modifications of the planned treatment. We observed that higher vitamin B2 concentrations were associated with lower risk of toxicities. Vitamin B6 and vitamin B12 were associated with the risk of toxicities in a nonlinear fashion, implying an optimal range of vitamin B6 and B12 concentrations. The association between folate and toxicities was dependent on genotypes of MTHFR C677T as well as folic acid supplement use. Overall, these observational data suggest that both deficient and excess B-vitamin concentrations, for example, due to prolonged supplementation, may be unfavourable in relation to toxicities of chemotherapy for CRC. Future studies are warranted to further investigate underlying biological mechanisms and evaluate whether nutrition-guided adjustments of B-vitamin concentrations could improve treatment tolerance."
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Additional Publications of Interest
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Dwyer LA, Agurs-Collins T, Bailey CP, Wolff-Hughes DL, Czajkowski S, Reedy J, Nebeling L. National Cancer Institute-supported obesity and cancer research, 2015-2022. JAMA Netw Open 2026 Aug 3;9(8):e2628773. PMID: 42584888
Agurs-Collins T, Sauter ER. GLP-1 receptor agonist use in cancer survivors - challenges and opportunities: a narrative review. Cancers (Basel) 2026;18(16):2714. PMID: 42650025
La Rocca F, Privitera G, Geraci C, Morello V, Geraci G, Paternò V, Santoro C, Esposito R. The MASLD-cardio-oncology triangle: dietary patterns, metabolic remodelling and implications for cancer therapy tolerance. Nutrients 2026;18(15):2527. PMID: 42588152
Habibzadeh P, Hurd D, Davar D. Making dietary modification in the immunotherapy era: from mechanistic evidence to practical implementation. Immunotherapy 2026 Aug 14:1-4. Epub ahead of print. PMID: 42596801
Compton SLE, Cho E, Spielmann G, Yi F, Yang S, Brown JC. Dietary fat, inflammation, circulating tumor cells, and circulating tumor DNA in colorectal cancer survivors: An exploratory cross-sectional study. J Acad Nutr Diet 2026 Aug 19:156830. Epub ahead of print. PMID: 42617694
Nafría M, Wesselink E, Kampman E, van Zutphen M, van Duijnhoven FJB, Kok DE, Romaguera D, Winkels RM. World Cancer Research Fund/American Institute for Cancer Research screener algorithm versus standard score: association with mortality in patients with colorectal cancer. Cancer Epidemiol Biomarkers Prev 2026;35(9):1573-1581. PMID: 42274335
Lavigne D, Allen L, Bijl A, Chan HAL, Dempster H, Macmillan L, Martin C, Nairn J, Partyka-Sitnik M, Shearing F, Trenholm R. The qualitative impact of the rural exercise for cancer patients and survivor programme (RECaPS). Can J Rural Med 2026;31(3):103-112. PMID: 42616934
Covington BW, Mattocks B, Krynski L, Simon LH, Hayward J, Villafana M, Lazio M, Hayward R. Exercise timing influences autonomic and psychological adaptations but not functional capacity in cancer patients undergoing treatment. Med Sci Sports Exerc 2026 Sep 1. Epub ahead of print. PMID: 42683581
Beggs M, Reid J, Hanna GG, Edgar A, Cotter S, Burke D, Prue G. 'You've given me my voice'- Enhancing engagement in exercise oncology research: a patient and public involvement approach to co‑designing a pre‑radiotherapy exercise programme with people living with lung cancer. Health Expect 2026 Aug;29(4):e70837. doi: 10.1111/hex.70837. PMID: 42644664
Querido NR, Bours MJL, Valkenburg-van Iersel L, Beijers AJM, Breukink SO, Janssen-Heijnen MLG, Keulen ETP, Konsten JLM, de Vos-Geelen J, Weijenberg MP, Simons CCJM. Associations of oxaliplatin dose, lean body mass, and sarcopenia with dose-limiting neuropathy in patients with colorectal cancer. Cancer Treat Res Commun 2026;48:101347. doi: 10.1016/j.ctarc.2026.101347. PMID: 42542077
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Call for Submissions: ASCO Educational Book
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Submit your reviews and expert insights to ASCO Educational Book, an open access publication, welcoming year-round, uninvited submissions. Explore our 3 new article types: State of the Science, Clinical Connections, and Innovations in Oncology Education. Plus, now through December 31st, all submitted manuscripts will receive a 50% discount on the article processing charges.
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National Institutes of Health (NIH) Virtual Seminar: Food is Medicine Research to Address Chronic Disease
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Tuesday, September 22, 2026, 1 - 3:30 PM ET
Sponsors: NIH Office of Nutrition Research, National Institute on Minority Health and Health Disparities
While the field of Food is Medicine (FIM) is expanding and multiple efforts are underway, particularly in the private sector, challenges remain including limited evidence of 1) consistent and robust improved health outcomes, 2) efficacy of long-term investments, 3) effective integration into clinical care, and 4) reductions in health care utilization and costs. The purpose of this seminar is to convene experts to discuss the current state of the science, research gaps and opportunities to advance FIM research, including interventions to promote health and reduce the burden of diet-related chronic diseases.
If you have any questions, please contact Allison Hurst in the Scientific Consulting Group at ahurst@scgcorp.com
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Invitation to Submit Additional Opportunities
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Opportunities such as training workshops, publication submissions, and funding applications are great to share with the EON Network. We invite all to submit relevant opportunities by emailing eonnetwork@bsc.gwu.edu!
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