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First authors listed in red, only Vanderbilt collaborators are listed except for first authors.
Week of August 21
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Recently published- Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity. The Journal of Clinical Investigation.
Ryan Ceddia, Analisa Thompson Gray, Feyisayo Adegboye, Ainsley McDonald-Boyer, Fubiao Shi, Dianxin Liu, Jose Maldonado, Julio Ayala, Owen McGuinness, Sheila Collins, Heidi Hamm.
- CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity. Journal of Molecular Biology.
Madison Adolph, Atharv Garje, Swati Balakrishnan, Walter Chazin, David Cortez.
- Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks. International Journal of Molecular Sciences.
Soziema Dauda, Jessica Collins, Jo Ann Byl, Neil Osheroff.
- Interplay between Nrf2 and αB-crystallin in the lens and heart of zebrafish under proteostatic stress. Frontiers in Molecular Biosciences.
Jinhee Park, Samantha MacGavin, Laurie Niederbrach, Hassane Mchaourab.
- Hitting the brakes on transcription to extend lifespan. Trends in Genetics.
Kristopher Burkewitz.
- Moving metals: How microbes deliver metal cofactors to metalloproteins. Molecular Microbiology.
Dillon Kunkle, Eric Skaar.
“Recent work from the [Eric Skaar lab] highlights recent advances that have implicated new classes of proteins in the distribution of metal ions within bacterial proteins, while speculating on the future of bacterial metallobiology,” VUMC Molecular Pathogenesis.
- Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade. Frontiers in Immunology.
Huan Qiao, Jozef Zienkiewicz, Yan Liu, Jacek Hawiger.
- Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly. Cell Reports.
Yihu Xie, Shengyan Gao, Bradley Clarke, Menghan Mei, Alexia Angelos, Pate Hill, Austin Ivey, Yi Ren.
- Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects. Journal of Clinical Investigation.
Sirle Saul (Stanford University), Jacquelyn Brown, John Wikswo.
- 2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery. Journal of Medicinal Chemistry.
Aaron Bender, Lauren Parr, William Livingston, Craig Lindsley, David Merryman.
- The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants in vitro. Xenobiotica.
Michiaki Kojima (Showa Pharmaceutical University), F. Peter. Guengerich.
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