School of Medicine Basic Sciences departments

Biochemistry

• Lipid-mediated mechanism of drug extrusion by a heterodimeric ABC exporter (preprint). bioRxiv.
  Qingyu Tang*, Paola Bisignano, Hassane Mchaourab*.

Cell and Developmental Biology

• Piezo-dependent surveillance of matrix stiffness generates transient cells that repair the basement membrane. Developmental Cell.
  Aubrie Stricker*, M Shane Hutson, Andrea Page-McCaw*.
  
  
• Empty spiracles homeobox 2 (EMX2) transcription factor functions as a tumor suppressor in renal cell carcinoma by targeting CADM1. Molecular Cancer Research.
  Zhibin Fu* (Changhai Hospital), Ethan Lee.
  
  
• Myelin transcription factors 1 and 3 have overlapping but distinct roles in insulin secretion and survival of human β cells (preprint). bioRxiv.
  Ruiying Hu*, Mahircan Yagan, Yu Wang, Xin Tong, Teri Doss, Jinhua Liu, Yanwen Xu, Alan Simmons, Ken Lau, Roland Stein, Qi Liu, Guoqiang Gu*.
  
  
• Insulin-like growth factor 2 (IGF2) as a driving force of exponential expansion and differentiation of neonatal thymus. Development.
  Seung Woo Kang* (The University of Georgia), Bryan Helm, Yu Wang, Ken Lau, Qi Liu.
  

Molecular Physiology and Biophysics

• Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression. npj Metabolic Health and Disease.
  Sandesh Marathe* (The University of Tennessee Health Science Center), Matthew Cottam, Kamran Idrees, Jeffrey Rathmell.

Pharmacology

• Shank3 modulates Rpl3 expression and protein synthesis via mGlu5: implications for Phelan McDermid syndrome. Molecular Psychiatry.
  Federica Giona* (CNR Neuroscience Institute), Stefania Beretta* (CNR Neuroscience Institute), Carrie Jones, P. Jeffrey Conn.
  
  
• Assembling the jigsaw puzzle of life. Trends in Biochemical Sciences.
  Vsevolod Gurevich*.
  

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