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Moores Member Andrew Lowy, MD is senior author on a new publication in Cancer Research that presents research identifying an enzyme MICAL2) responsible for promoting tumor growth and spread in pancreatic cancer, suggesting that MICAL2 holds promise as a target for new treatments. Learn More>>

Moores Members Jack Bui, MD, PhD, Enfu Hui, PhD, Li-Fan Lu, PhD, and Gerald Morris, MD, PhD have found that PD-1, a protein targeted in cancer immunotherapy, functions differently in humans and mice. The mouse version is weaker, which may limit the effectiveness of treatments developed through rodent studies. Learn More>>

This is a collaborative event to empower patients, support caregivers, and engage advocates in advancing prostate cancer care. Moores Members will be presenting, alongside special guest John Elway Jr. Learn More and Register>>

Moores Members Michael Karin, PhD and Ludmil Alexadrov, PhD have uncovered how cellular metabolism and DNA damage drive fatty liver disease to become liver cancer, contributing to understanding the origins of cancer and the identification of strategies for improved prevention and treatment. Learn More>>

This workshop will convene experts in immuno-oncology, gene and cell engineering, and nanomaterial delivery to not only explore the latest breakthroughs in in vivo immune cell engineering, but also engage in enlightened discussions, learn from multidisciplinary pioneers, and shape the future of cellular immunotherapy. Register Now>>

This year’s symposium will be held January 28, 2025 at the Scripps Seaside Forum and feature Lewis Cantley, PhD, Professor of Cell Biology at Harvard Medical School, who will present “A Technology for Linking Protein Kinases to Protein Phosphorylation Sites to Reveal Mechanisms of Cellular Regulation in Normal and Diseased Tissues.” The symposium includes lunch, short talks with specialists from UC San Diego and Pfizer, and a poster session. Learn More & Register>>

The Researcher Spotlight is designed to help you connect with fellow researchers, gain insights into their diverse projects, and discover the paths that led them to their current roles. Uncover a personal touch to their professional achievements, showcasing the varied perspectives within our cancer research community.

Trey Ideker, PhD, is a 21-year Professor of Medicine, Bioengineering and Computer Science, and former Chief of Genetics, at the University of California San Diego (UCSD). Additionally, he is Director or Co-Director of the Bridge2AI Functional Genomics Data Generation Program, the Cancer Cell Map Initiative, the National Resource for Network Biology, and the UCSD Graduate Program in Bioinformatics and Systems Biology, all NIH-funded efforts. Ideker’s research laboratory has led seminal studies establishing the theory and practice of systems biology, including systematic techniques for elucidating human cell architecture and its molecular networks.

Nature

Shuvro P. Nandi, PhD (Structural and Functional Genomics [SFG]), Debanjan Dhar, PhD (Solid Tumor Therapeutics [STT]), 

Tatiana Kisseleva, MD, PhD (Cancer Biology and Signaling)

Ludmil B. Alexandrov, PhD (SFG), and Michael Karin, PhD (STT)

Nature

Vineet Bafna, PhD (Structural and Functional Genomics)

Cancer Research

Pablo Tamayo, PhD (Structural and Functional Genomics [SFG]), Jill P. Mesirov, PhD (SFG), Herve Tiriac, PhD (Solid Tumor Therapeutics [STT]), and Andrew M. Lowy, MD (STT)

RP1-104: Randomized, Phase III Clinical Study Comparing Vusolimogene Oderparepvec in Combination With Nivolumab vs Treatment of Physicians Choice in Patients with Advanced Melanoma That Progressed on Anti-PD1 and Anti-CTLA4 Containing Treatment

PI: Gregory Daniels, MD, PhD

NCT: NCT06264180

 

AFT-57: Randomized Phase II Trial of Neoadjuvant and Adjuvant Atezolizumab with or Without Tiragolumab in Conjunction with Chemoradiotherapy for Unresectable Stage III NSCLC

PI: James Urbanic, MD

NCT: NCT05798663

Prior to the holidays, COE enhanced connections with and provided vital resources to the catchment area at the San Diego LGBT Community Center annual gathering. COE Liaisons Alexia and Dahlia distributed an LGBTQIA+ needs assessment to better understand the health concerns of this community. 

COE collaborated with local organizations for a toy drive in Southeast San Diego, which provided support for flood survivors and delivered holiday cheer to families in need. COE will continue to create opportunities to connect with diverse groups, listen to community needs, and foster awareness of cancer health resources in 2025.

Department of Research Administration

3855 Health Sciences Drive, La Jolla, CA 92037

moorescancercenter.ucsd.edu

 

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