MP faculty publications: February 2023

1. Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels

   Shen Q, Feng Q, Wu C, Xiong Q, Tian T, Yuan S, Shi J, Bedwell GJ, Yang R, Aiken C, Engelman AN, Lusk CP, Lin C, Xiong Y.
   Nat Struct Mol Biol. 2023 Feb 20.

2. Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

   Rosain J, Neehus AL, Manry J, Yang R, Le Pen J, Daher W, Liu Z, Chan YH, Tahuil N, Türel Ö, Bourgey M, Ogishi M, Doisne JM, Izquierdo HM, Shirasaki T, Le Voyer T, Guérin A, Bastard P, Moncada-Vélez M, Han JE, Khan T, Rapaport F, Hong SH, Cheung A, Haake K, Mindt BC, Pérez L, Philippot Q, Lee D, Zhang P, Rinchai D, Al Ali F, Ahmad Ata MM, Rahman M, Peel JN, Heissel S, Molina H, Kendir-Demirkol Y, Bailey R, Zhao S, Bohlen J, Mancini M, Seeleuthner Y, Roelens M, Lorenzo L, Soudée C, Paz MEJ, González ML, Jeljeli M, Soulier J, Romana S, L'Honneur AS, Materna M, Martínez-Barricarte R, Pochon M, Oleaga-Quintas C, Michev A, Migaud M, Lévy R, Alyanakian MA, Rozenberg F, Croft CA, Vogt G, Emile JF, Kremer L, Ma CS, Fritz JH, Lemon SM, Spaan AN, Manel N, Abel L, MacDonald MR, Boisson-Dupuis S, Marr N, Tangye SG, Di Santo JP, Zhang Q, Zhang SY, Rice CM, Béziat V, Lachmann N, Langlais D, Casanova JL, Gros P, Bustamante J.
   Cell. 2023 Feb 2;186(3):621-645.e33.

3. Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells

   Jacobse J, Brown RE, Li J, Pilat JM, Pham L, Short SP, Peek CT, Rolong A, Washington MK, Martinez-Barricarte R, Byndloss MX, Shelton C, Markle JG, Latour YL, Allaman MM, Cassat JE, Wilson KT, Choksi YA, Williams CS, Lau KS, Flynn CR, Casanova JL, Rings EHHM, Samsom JN, Goettel JA.
   Cell Rep. 2023 Feb 17;42(2):112128.

4. Case Studies in the Assessment of Microbial Fitness: Seemingly Subtle Changes Can Have Major Effects on Phenotypic Outcomes

   Worthan SB, McCarthy RDP, Behringer MG.
   J Mol Evol. 2023 Feb 8.

5. Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility

   Islam ST, Jolivet NY, Cuzin C, Belgrave AM, My L, Fleuchot B, Faure LM, Mahanta U, Kezzo AA, Saïdi F, Sharma G, Fiche JB, Bratton BP, Herrou J, Nollmann M, Shaevitz JW, Durand E, Mignot T.
   Sci Adv. 2023 Feb 22;9(8):eabq0619.

6. Machine-Learning Model for Prediction of Cefepime Susceptibility in Escherichia coli from Whole-Genome Sequencing Data

   Humphries RM, Bragin E, Parkhill J, Morales G, Schmitz JE, Rhodes PA.
   J Clin Microbiol. 2023 Feb 22:e0143122.

7. Treatment with Helicobacter pylori-derived VacA attenuates allergic airway disease

   Reuter S, Raspe J, Uebner H, Contoyannis A, Pastille E, Westendorf AM, Caso GC, Cover TL, Müller A, Taube C.
   Front Immunol. 2023 Jan 24;14:1092801.

8. Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women

   Clasey JL, Adams AM, Geiger PJ, Segerstrom SC, Crofford LJ.
   Womens Health Rep (New Rochelle). 2020 Dec 28;1(1):584-591.

9. Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis

   Rghei AD, Yates JGE, Lopes JA, Zhan X, Guilleman MM, Pei Y, van Lieshout LP, Santry LA, Bridle BW, Karimi K, Thompson B, Susta L, Crowe JE Jr, Wootton SK.
   Gene Ther. 2023 Feb 2.

10. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages

    Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie KP, Waterson AG, Doran AC, Sulikowski GA, Davies SS.
    bioRxiv [Preprint]. 2023 Jan 25:2023.01.25.525554.

11. Alignment, segmentation and neighborhood analysis in cyclic immunohistochemistry data using CASSATT

    Brockman AA, Khurana R, Bartkowiak T, Thomas PL, Sivagnanam S, Betts CB, Coussens LM, Lovly CM, Irish JM, Ihrie RA
    Cytometry B Clin Cytom. 2023 Feb 7.

12. Human Leukocyte Antigen Genotyping of Idiopathic Subglottic Stenosis

    Rohlfing ML, Hillel AT, Wohler E, Sobreira N, Phillips EJ, Mallal SA, Gelbard A.
    Laryngoscope. 2023 Feb 2.

13. Mucosal gene expression in response to SARS-CoV-2 is associated with early viral load

    Rajagopala SV, Strickland BA, Pakala SB, Kimura KS, Shilts MH, Rosas-Salazar C, Brown HM, Freeman MH, Wessinger BC, Gupta V, Phillips E, Mallal SA, Turner JH, Das SR.
    bioRxiv [Preprint]. 2022 Aug 23:2022.08.23.504908.

14. Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities

    Patterson AR, Needle GA, Sugiura A, Chi C, Steiner KK, Fisher EL, Robertson GL, Bodnya C, Markle JG, Gama V, Rathmell JC.
    bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525419

15. Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas

    Wright JJ, Williams JM, Letourneau-Freiberg LR, Kandasamy B, Reyes D, Kanegusuku AG, Philipson L, Greeley SAW, Hilmes MA, Powers AC, Virostko J, Moore DJ.
    Diabetes Care. 2023 Feb 1:dc222082

16. Rare structural variants, aneuploidies, and mosaicism in individuals with Mullerian aplasia detected by optical genome mapping

    Brakta S, Hawkins ZA, Sahajpal N, Seman N, Kira D, Chorich LP, Kim HG, Xu H, Phillips JA 3rd, Kolhe R, Layman LC
    Hum Genet. 2023 Feb 17.

17. Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics

    Kim M, McDonald EF, Sabusap CMP, Timalsina B, Joshi D, Hong JS, Rab A, Sorscher EJ, Plate L.
    bioRxiv [Preprint]. 2023 Feb 4:2023.02.04.527134.

18. Developmental Trajectory of Extracellular Vesicles Characteristics from the Lungs of Preterm Infants

    Ransom MA, Bunn KE, Negretti NM, Jetter CS, Bressman ZJ, Sucre JMS, Pua HH
    Am J Physiol Lung Cell Mol Physiol. 2023 Jan 31.

19. Sprenkle NT, Serezani CH, Pua HH.

    authors
    J Immunol. 2023 Feb 15;210(4):359-368.

20. Metabolic programming and immune suppression in the tumor microenvironment

    Arner EN, Rathmell JC.
    Cancer Cell. 2023 Feb 9:S1535-6108(23)00009-0.

21. Uncovering the fascinating world of amphibian immunity

    Katzenback BA, Rollins-Smith LA.
    Dev Comp Immunol. 2023 Feb 3;142:104655.

22. The importance of antimicrobial peptides (AMPs) in amphibian skin defense.

    Rollins-Smith LA.
    Dev Comp Immunol. 2023 Feb 6;142:104657.

23. Identification of Degenerated Murine Facial Nerves With Fluorescence Labeling After Transection Injury

    Crawford KL, Lee YJ, Hom M, Rosenthal EL, Orosco RK, Nguyen QT.
    Otolaryngol Head Neck Surg. 2023 Feb 9. doi: 10.1002/ohn.262.

24. WPOI-5: Accurately Identified at Intraoperative Consultation and Predictive of Occult Cervical Metastases

    Beute JE, Greenberg LA, Wein LE, Kapustin DA, Fan J, Dowling EM, Samankan S, Matloob A, Xing M, Modica I, Chung D, Carroll W, Rosenthal EL, Khan MN, Chai RL, Brandwein-Weber MS, Urken ML.
    Head Neck Pathol. 2023 Feb 28.

25. Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study

    Coupland LA, Rabbolini DJ, Schoenecker JG, Crispin PJ, Miller JJ, Ghent T, Medcalf RL, Aneman AE.
    Crit Care. 2023 Feb 10;27(1):55.

26. Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis

    Chora ÂF, Marques S, Gonçalves JL, Lima P, Gomes da Costa D, Fernandez-Ruiz D, Marreiros MI, Ruivo P, Carvalho T, Ribeiro RM, Serre K, Heath WR, Silva-Santos B, Tate AT, Mota MM.
    Immunity. 2023 Feb 14:S1074-7613(23)00043-2.

27. Anti-biofilm Activity of Human Milk Oligosaccharides in Clinical Strains of Streptococcus agalactiae with Diverse Capsular and Sequence

    Moore RE, Spicer SK, Talbert JA, Manning SD, Townsend SD, Gaddy JA.
    Chembiochem. 2023 Jan 9:e202200643.

28. Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy

    Hoogenboezem EN, Patel SS, Cavnar AB, Lo JH, Babb LM, Francini N, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL.
    bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528574.

29. Hemoglobin increases leukocyte adhesion and initiates lung microvascular endothelial activation via Toll-like receptor 4 signaling

    Conger AK, Tomasek T, Riedmann KJ, Douglas JS, Berkey LE, Ware LB, Bastarache JA, Meegan JE.
    Am J Physiol Cell Physiol. 2023 Mar 1;324(3):C665-C673.

30. Context-specific regulation of extracellular vesicle biogenesis and cargo selection

    Dixson AC, Dawson TR, Di Vizio D, Weaver AM.
    Nat Rev Mol Cell Biol. 2023 Feb 10.

31. Niche tension controls exosome production

    Dixson AC, Dawson TR, Di Vizio D, Weaver AM.
    Nat Cell Biol. 2023 Feb 16.

32. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling

    Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E.
    Sci Signal. 2023 Feb 7;16(771):eabn8372.