| LAC DPH Health Advisory:
Updates to Fall 2025 Respiratory Virus Vaccine Recommendations in California
October 2, 2025
Correction posted: October 3, 2025
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This message is intended for vaccine providers, pediatricians, obstetricians, and primary care providers in Los Angeles County.
Please distribute as appropriate.
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Correction (10/3/25): The original version of this HAN (released 10/2/25) contained an error in the Key Messages section. It incorrectly stated that RSV vaccine recommendations remain unchanged. In fact, recommendations have been expanded to include adults aged 50–59 years with risk factors. This has been corrected in the current version.
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On September 17th, 2025, California Governor Newsom signed Assembly Bill (AB) 144. This law shifts the authority for setting California’s vaccine recommendations from the Centers for Disease Control and Prevention (CDC)’s Advisory Committee for Immunization Practices (ACIP) to the California Department of Public Health (CDPH).
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As a result, all providers in California should now follow CDPH vaccine recommendations which may differ from those issued by ACIP.
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Under AB 144, vaccines recommended by CDPH must be covered by California Health Plans, including Medi-Cal managed care plans. This means that these insurance plans will cover vaccines recommended by CDPH even if ACIP does not recommend them.
- This bill also provides liability protection to providers who administer vaccines based on CDPH recommendations. Additionally, it allows pharmacists to independently initiate and administer immunizations recommended by CDPH.
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Per CDPH’s 2025–26 Respiratory Vaccine Recommendations, all Californians 6 months and older who choose protection are recommended to receive updated COVID-19 vaccines. Influenza vaccine recommendations remain unchanged from last year, and RSV vaccine recommendations for older adults have been expanded to include adults aged 50-59 years with risk factors (see below for details).
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In June 2025, HHS Secretary Robert F. Kennedy Jr. dismissed all 17 standing members of the ACIP, citing concerns about potential conflicts of interest. However, previous reports found no evidence of such issues. New members were appointed, including individuals who have publicly questioned aspects of vaccine policy.
The changes at ACIP coincided with broader leadership shifts at the CDC, including the dismissal of the Director and the resignation of several senior officials. Some of these officials expressed concerns about the agency’s direction and the influence of politics on public health decisions.
During this time of uncertainty and confusion regarding vaccines, including COVID-19 vaccine eligibility, CDPH released its vaccine recommendations (see Consensus WHCA Recommendations below). They were developed in collaboration with the West Coast Health Alliance (WCHA) partners Oregon, Washington and Hawaii, and informed by national medical organizations including: American Academy of Pediatrics (AAP), American College of Obstetricians and Gynecologists (ACOG), and American Academy of Family Physicians (AAFP).
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Concurrently, AB 144 was signed into law, establishing a baseline for immunization recommendations for California based on the federal ACIP immunization recommendations in effect on January 1, 2025. After this date, CDPH is authorized to update recommendations as needed, taking into consideration emerging science and guidance from professional organizations.
Under AB 144, all vaccines recommended by CDPH must be covered by health insurance regulated by the Department of Managed Care Health Care, including HMOs and Medi-Cal managed care plans. Federal insurance programs such as Medicare and some PPO’s do not fall under this new state law. However, America's Health Insurance Plans (AHIP) has committed to covering all ACIP recommended immunizations including updated formulations of COVID-19 vaccines with no cost-sharing for patients through the end of 2026.
Additionally, Providers administering vaccines recommended by CDPH are protected from liability and pharmacists may independently administer immunizations recommended by CDPH to patients three years and older, without a prescription.
Finally, on September 19th, ACIP voted to endorse a model of individual decision making (e.g. shared clinical decision-making) between a patient and their healthcare provider. Although these recommendations do not become federal policy guidance until the acting CDC Director, in the absence of a permanent CDC Director, signs a decision memo, this vote indicates that COVID-19 vaccines will likely be covered by the VFC Program, and there will be no cost-sharing for all individuals aged 6 months and older. ACIP Meeting Slides on COVID-19 vaccines may be found here.
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Consensus WCHA 2025-2026 Respiratory Virus Season Immunization Recommendations
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Actions Requested of Providers
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- Administer influenza vaccine to all persons 6 months and older.
- Children under the age 9 may need 2 doses of influenza vaccine if they have not previously received vaccine in previous years
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Older adults over the age of 65 should get recombinant, adjuvanted, or high dose influenza vaccines
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- Administer RSV immunizations to eligible patients including:
- All adults aged 75 years and older who have not previously received an RSV vaccine dose (Abrysvo, Arexvy, mResvia)
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Adults aged 50-74 years with certain underlying medical conditions that increase their risk for severe RSV who have not previously received an RSV vaccine (Abrysvo, Arexvy, mResvia)
- Pregnant persons 32-36 weeks pregnant during September through January (Abrysvo)
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Infants younger than 8 months of age who are born during or are entering their first RSV season (October through March) if:
- the mother did not receive RSV vaccine during pregnancy, or
- the mother’s RSV vaccination status is unknown, or
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the infant was born within 14 days of maternal RSV vaccination.(nirsevimab/Beyfortus or clesrovimab/Enflonsia)
- Children 8-19 months at high risk for severe RSV disease and entering their second RSV season (October through March) (nirsevimab/Beyfortus)
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Administer COVID-19 vaccines to all persons 6 months and older who desire protection. Prioritize vaccine for those:
- 65 years and older
- Who are planning pregnancy, pregnant, postpartum, or lactating
- Infants 6–23 months and children 2-18 years old who have never been vaccinated for COVID-19
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Individuals with risk factors that put them at increased risk for severe disease
- Individuals who are in close contact with others with risk factors
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Educate and reassure patients that recommended vaccines remain safe and effective, particularly for those at higher risk of severe disease.
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This communication was sent by Dr. Nava Yeganeh, Medical Director, Vaccine Preventable Disease Control Program, Los Angeles County Department of Public Health.
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To view this LAHAN in PDF format, view past communications, or sign-up to receive LAHANs, please visit ph.lacounty.gov/lahan.
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