Vanderbilt University | School of Medicine – Basic Science

“The Reading List” in dark teal with a drawing, in gold tones, of a person with long hair, sitting cross legged and reading a book.

First authors listed in red, only Vanderbilt collaborators are listed except for first authors.

Week of June 5

Recently published

General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants. Cell Chemical Biology.
Andrew McKee (Indiana University), Eli McDonald, Jens Meiler, Lars Plate.

“In our collaboration w/ the Schlebach Lab at UI, we characterize the drug response of 129 CFTR variants using deep mutational scanning,” Eli Fritz McDonald.
Functional Role of Arrestin-1 Residues Interacting with Unphosphorylated Rhodopsin Elements. International Journal of Molecular Sciences.
Sergey Vishnivetskiy, Liana Weinstein, Chen Zheng, Eugenia Gurevich, Vsevolod Gurevich.
Modulation of Membrane Trafficking of AQP5 in the Lens in Response to Changes in Zonular Tension Is Mediated by the Mechanosensitive Channel TRPV1. International Journal of Molecular Sciences.
Rosica Petrova (The University of Auckland), Kevin Schey.
In the Age of Machine Learning Cryo-EM Research is Still Necessary: A Path toward Precision Medicine. Advanced Biology.
Dominique Stephens, Amber Crabtree, Heather Beasley, Edgar Garza-Lopez, Larry Vang, Kit Neikirk, Zer Vue, Neng Vue, Andrea Marshall, Jennifer Gaddy, Antentor Hinton Jr.
Conformational flexibility underlies the versatility of arrestins. BioEssays.
Vsevolod Gurevich.
Serial Block Face-Scanning Electron Microscopy as a Burgeoning Technology. Advanced Biology.
Andrea Marshall, Kit Neikirk, Dominique Stephens, Larry Vang, Zer Vue, Heather Beasley, Amber Crabtree, Edgar Garza Lopez, Bryanna Shao, Evan Krystofiak, Antentor Hinton Jr.
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics. eLife.
Ziva Vuckovic (Monash University), Jinan Wang (University of Kansas), Vi Pham (Monash University), Jesse Mobbs (Monash University), Craig Lindsley.

Preprints

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. bioRxiv.
Qingyu Tang, Richard Stein, Erkan Karakas, Hassane Mchaourab.

“Our recent manuscript [reports] an integrated cryoEM/DEER/MD simulations investigation of an ABC transporter,” Hassane Mchaourab lab.

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Preprints

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