The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
Week of March 3
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School of Medicine Basic Sciences departments Cell and Developmental Biology- Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties. Nature Cell Biology.
Dennis Jeppesen*, Zachary Sanchez*, Noah Kelley, James Hayes, Jessica Ambroise, Emma Koory, Evan Krystofiak, Nilay Taneja, Qin Zhang, Matthew Dungan, Olivia Perkins, Matthew Tyska, Ela Knapik, Amanda Doran, Robert Coffey, Dylan Burnette*.
Supported by the Vanderbilt Cell Imaging Shared Resource and the Proteomics Core.
- The Great Reset: A "Tuft" Journey Towards Tumorigenesis. Cellular and Molecular Gastroenterology and Hepatology.
Monica Brown*, Ken Lau*.
Molecular Physiology and Biophysics- Salt sensitivity of blood pressure: mechanisms and sex-specific differences. Nature Reviews Cardiology.
Sepiso Masenga*, Nelson Wandira, Mohammad Saleem, Heather Beasley, Antentor Hinton Jr., Lale Ertuglu, Naome Mwesigwa, Annet Kirabo*.
- Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes. Trends in Cell Biology.
Woo Yong Park*, Claudia Montufar, Elma Zaganjor*.
- Artificial intelligence-enabled automated analysis of transmission electron micrographs to evaluate chemotherapy impact on mitochondrial morphology in triple negative breast cancer (preprint). bioRxiv.
Argenis Arriojas* (University of Massachusetts Boston), Antentor Hinton Jr.
Pharmacology- Antigenic determinants underlying IgE-mediated anaphylaxis to peanut. Journal of Allergy and Clinical Immunology.
Scott Smith*, Yasmin Khan, Rebecca Shrem, Jonathan Hemler, Joshua Doyle, Jacob Daniel, Jian Zhang, R. Stokes Peebles Jr., Benjamin Spiller.
and
Structural determinants of peanut induced anaphylaxis. Journal of Allergy and Clinical Immunology.
Scott Smith*, Rebecca Shrem, Bruno Lança, Jian Zhang, R. Stokes Peebles Jr., Benjamin Spiller*.
Basic Sciences: Vanderbilt biomedical research paves the way for ‘hypoallergen’ treatments against peanut allergies
- Discovery of ONO-2920632 (VU6011887): A Highly Selective and CNS Penetrant TREK-2 (TWIK-Related K+ Channel 2) Preferring Activator In Vivo Tool Compound. ACS Chemical Neuroscience.
Kentaro Yashiro* (Ono Pharmaceutical Co.), Joshua Wieting, Kevin McGowan, Thomas Bridges, Olivier Boutaud, Darren Engers, Jerod Denton, Craig Lindsley*.
- Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking. Nature Communications.
Zahra Farahbakhsh*, Alberto López, Cody Siciliano*.
Basic Sciences: Research Snapshot: How alcohol reshapes the brain’s dopamine system long after drinking stops
- Oxidative Stress Causes Mitochondrial and Electrophysiologic Dysfunction to Promote Atrial Fibrillation in Pitx2+/-Mice. Circulation: Arrhythmia and Electrophysiology.
Tuerdi Subati*, Kyungsoo Kim*, Zhenjiang Yang, Matthew Murphy, Joseph Van Amburg, Isis Christopher, Owen Dougherty, Kaylen Woodall, Charles Smart, Joyce Johnson, Agnes Fogo, Venkataraman Amarnath, Vineet Agrawal, Joey Barnett, Katherine Murray*.
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First or corresponding authors are identified with an *. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.
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