School of Medicine Basic Sciences departments

Biochemistry

• Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates. Investigative Ophthalmology & Visual Science.
  Zhen Wang*, Kevin Schey*.

Cell and Developmental Biology

• Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development. Nature Neuroscience.
  Ya'el Courtney* (Harvard Medical School), Neil Dani.

Molecular Physiology and Biophysics

• Beta 2 adrenergic receptor gene methylation activates innate lymphoid cells to drive hypertension in lymphocyte deficient hosts. Cardiovascular Research.
  Wei Chen*, Marwa Abd-ElDayem, Elizabeth Hennen, Luis Miguel Rivera-Medina, David Patrick, Mingfang Ao, Shilin Zhao, David Harrison*.
  
  
• Regulatory Roles of Long Noncoding RNAs in Arterial Stiffness and Hypertension. Hypertension.
  Jose Vargas* (Washington VA Medical Center), Han Le, Antentor Hinton Jr.

Pharmacology

• Enhanced ERK activity extends ketamine's antidepressant effects by augmenting synaptic plasticity. Science.
  Z. Zack Ma*, Natalie Guzikowski, Ji-Woon Kim, Ege Kavalali, Lisa Monteggia*.
  
  Earth.com: Ketamine treatment may now last months instead of weeks
  
  
• N-Aldehyde-Modified Phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-Acyl Phosphatidylethanolamine Phospholipase D. Journal of Lipid Research.
  Reza Fadaei*, Annie Bernstein, Jonah Zarrow, Abdul-Musawwir Alli-Oluwafuyi, Keri Tallman, Sean Davies*.
  
  
• Alzheimer’s Disease Sequencing Project release 4 whole genome sequencing dataset. Alzheimer’s & Dementia.
  Yuk Yee Leung* (University of Pennsylvania), Shannon Turner, Timothy Hohman.
  
  
• Discovery of Pre-Clinical Candidate VU6008055/AF98943: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy. ACS Chemical Neuroscience.
  Julie Engers*, Sean Bollinger, Alison Gregro, Rory Capstick, Paul Spearing, Madeline Long, James Tarr, Katherine Watson, Sichen Chang, Vincent Luscombe, Alice Rodriguez, Hyekyung Cho, Aidong Qi, Colleen Niswender, Michael Bubser, Robert Gould, William Robb, Nellie Byun, John Gore, Carrie Jones, Morten Thomsen, Thomas Bridges, Olivier Boutaud, P. Jeffrey Conn, Darren Engers, Craig Lindsley*, Kayla Temple*.
  
  
• Characterization of Novel and Known Activators of Cannabinoid Receptor Subtype 2 Reveals Mixed Pharmacology That Differentiates Mycophenolate Mofetil and GW-842,166X from MDA7. International Journal of Molecular Sciences.
  Alice Rodriguez*, Aidong Qi, Allie Han, Haley Kling, Marc Quitalig, Aaron Bender, Lisa Barbaro, David Whomble, Craig Lindsley, Colleen Niswender*.
  
  
• Increased sedentary behavior is associated with neurodegeneration and worse cognition in older adults over a 7-year period despite high levels of physical activity. Alzheimer’s & Dementia.
  Marissa Gogniat*, Omair Khan, Judy Li, W. Hudson Robb, Panpan Zhang, Yunyi Sun, Elizabeth Moore, Michelle Houston, Kimberly Pechman, Niranjana Shashikumar, L. Taylor Davis, Dandan Liu, Bennett Landman, Keith Cole, Corey Bolton, Katherine Gifford, Timothy Hohman, Kelsie Full, Angela Jefferson*.
  
  Vice: Sitting Is Quietly Killing Your Brain, Even If You Exercise
  

Have a paper you want featured?

Tell us before you publish