Childhood Exposure to Bacterial Toxin Could Be Driving Youth Colorectal Cancer Epidemic
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Led by Moores Member Ludmil B. Alexandrov, PhD, an international team has identified a DNA mutation pattern linked to early-life exposure to the bacterial toxin colibactin, which suggests that this microbial agent may be behind the global surge in early-onset colorectal cancer. Learn More>>
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High Cannabis Use Linked to Increased Mortality Among Colon Cancer Patients
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Moores Member Rafael E. Cuomo, PhD, MPH, CPH, FRSPH analyzed over 1,000 UC Health colon cancer patient records (2012–2024) and found that those patients with a history of high cannabis use before diagnosis exhibited a higher mortality rate within 5 years, after adjusting for age, sex, tumor stage, and biomarkers. Learn More>>
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Behind Every Breakthrough at UC San Diego
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UC San Diego faculty are making new discoveries that provide hope for rare cancers and advance stem cell treatments once thought impossible. This research requires resources, collaboration, and investment to convert possibility to reality. Several Moores Members participate in this research that is transforming the future of cancer care. Learn More>>
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Key Lipid Metabolism Enzyme Linked to Immune System Aging
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Moores Member Leslie Crews, PhD has found that reduced activity of the ELOVL2 enzyme speeds up white blood cell aging and affects the expression of genes linked to cancer. Learn More>>
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Children with MASLD Face Dramatically Higher Risk of Early Death
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Children facing this liver disease underscores the importance of early detection, ongoing care, and greater public and provider awareness, according to research by Moores Member, Jeffrey B. Schwimmer, MD. Learn More>>
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Health Innovation Translation Symposium (HITS)
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The half-day HITS will take place this Friday, May 2, 2025. With contributions from Morrison Foerster and Silicon Valley Bank, HITS spotlights legal, financial, and strategic insight to accelerate health innovations in becoming therapies. Discover core facilities, connect with founders, and explore the next wave of health solutions. Register Now and Learn More>>
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MOORES CANCER CENTER AT AACR |
At the AACR Annual Meeting 2025, is taking place through April 30, 2025 in Chicago, IL, where our physician-scientists are presenting key findings on immunology, computational biology and early detection and prevention through more than 30 sessions.
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Science in Session: TREY IDEKER, PHD
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Learn more about Dr. Ideker's innovative research that will enable oncologists to more precisely diagnose and treat patients with cancer.
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| Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer
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Herve Tiriac, PhD (Solid Tumor Therapeutics [STT]) and Andrew M. Lowy, MD, FACS (STT)
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| Geographic and age variations in mutational processes in colorectal cancer
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Erik N. Bergstrom, PhD (Structural and Functional Genomics [SFG]) and Ludmil B. Alexandrov, PhD (SFG)
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| Long-term mortality and extrahepatic outcomes in 1,096 children with MASLD: A retrospective cohort study
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Jeffrey B. Schwimmer, MD (Non-programmatically Aligned)
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CLINICAL TRIALS OFFICE (CTO)
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MB-105-201: A Phase 2, Open-label, Multicenter Study of MB105 in Patients With CD5 Positive (CD5) Relapsed / Refractory T-cell Lymphoma (r/r TCL)
PI: Aaron Goodman, MD
NCT ID: NCT06534060
CONVERGE-01: A Phase 2, Open-label Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac225 Rosopatamab Tetraxetan in Participants with PSMA PET-Positive Castration-Resistant Prostate Cancer
PI: Rana McKay, MD
NCT ID: NCT06549465
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