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January 27, 2025

Location Influences How Immune System Fights Disease

Moores Members Ananda Goldrath, PhD, and Miguel Reina-Campos, PhD, have found that tissue-resident memory CD8 T cells play unique and specialized roles, depending on where they are located in the small intestine. Learn More>>

Reception Honoring Haydee Ojeda-Fournier, MD

Moores Member Haydee Ojeda-Fournier, MD, has been appointed as the inaugural Grillo-Marxuach Family Endowed Medical Director in Breast Imaging at UC San Diego Health. A celebratory reception will be held Friday, January 31, 2025 from 2:00 p.m. to 4:00 p.m. in the Moores Goldberg Auditorium. RSVP Now>>

UC San Diego Prostate Cancer Summit

The UC San Diego Prostate Cancer Summit, hosted by Moores and the Prostate Cancer Foundation, will commence this Friday and feature guest speaker and NFL Super Bowl XXXIII MVP, John Elway. Learn More and Register>>

EDUCATION

 

Fourth Annual Rising Stars Symposium at Sanford Burnham Prebys

From April 30, 2025 to May 2, 2025, late-stage doctoral students and early-stage postdoctoral researchers who are seeking postdoctoral positions through May 2026 will have the opportunity to showcase their work and network for career advancement. Learn More and Apply>>

FEATURED FUNDING OPPORTUNITIES

 

Solving the Early Detection and Early-Stage Diagnosis of Recalcitrant Cancers

To encourage innovation in research to detect the deadliest cancers at earlier stages, the American Association for Cancer Research, the Lustgarten Foundation, and the Mark Foundation for Cancer Research welcome proposals for projects to accelerate the development of new approaches for the early detection of the following types of cancer:pancreatic cancer, hepatobiliary cancers (hepatocellular carcinoma; gallbladder and bile duct cancers; cholangiocarcinoma), ovarian cancer, glioblastoma, upper GI cancers (esophageal; gastric cancer), and cancers resulting from hereditary cancer predisposition syndromes.

LOI Deadline: March 10, 2025

Application Deadline: June 17, 2025

Budget: $2,000,000 for 2 years

NCI Pathway to Independence Award (K99/R00 – Clinical Trial Required)

Application Deadline: February 27, 2025

Budget: Up to $100,000/year toward salary 

RESEARCHER SPOTLIGHT

 

The Researcher Spotlight is designed to help you connect with fellow researchers, gain insights into their diverse projects, and discover the paths that led them to their current roles. Uncover a personal touch to their professional achievements, showcasing the varied perspectives within our cancer research community.

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MARIA ELENA MARTINEZ, PHD

Maria Elena Martinez, PhD, is a Professor in the Department of Family and Preventive Medicine, having joined the UC San Diego faculty in 2012. She holds the Sam M. Walton Endowed Chair for Cancer Research and is the Associate Director of Population Science at Moores Cancer Center. Dr. Martinez's research is focused in the areas of epidemiology, molecular epidemiology, and cancer prevention.

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RECENT PUBLICATIONS

 

Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted

Nature

Miguel Reina-Campos, PhD (Cancer Biology and Signaling [CBS]), Gene W. Yeo, PhD (Hematologic Malignancies [HEM]), John T. Chang, MD (CBS), and Ananda W. Goldrath, PhD (HEM)

Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data

Nature Communications

Kathleen Curtius, PhD (Cancer Control) and Rob Knight, PhD (Structural and Functional Genomics)

Intratumoral or subcutaneous MK-2118, a non-cyclic dinucleotide STING agonist, with or without pembrolizumab for advanced or metastatic solid tumors or lymphomas

Clinical Cancer Research

Sandip P. Patel, MD (Solid Tumor Therapeutics)

CLINICAL TRIALS OFFICE (CTO)

 

CLINICAL TRIALS

AB248-101: An Open-Label Phase Ia/IIb Dose-Escalation and Expansion Study Investigating the Safety, Pharmacokinetics, Pharmacodynamics, and Activity of AB248 Alone or in Combination with Pembrolizumab in Adult Patients with Locally Advanced or Metastatic Solid Tumors

PI: Gregory Daniels, MD, PhD

NCT: NCT05653882

 

IMC-F106C-301: A Phase III Randomized, Controlled Study of IMCF106C Plus Nivolumab Versus Nivolumab Regimens in HLAA02:01 Positive Participants with Previously Untreated Advanced Melanoma (PRISMMEL301)

PI: Gregory Daniels, MD, PhD

NCT: NCT06112314

COMMUNITY OUTREACH AND ENGAGEMENT (COE)

 

Pictured (left to right) are Krzel Manansala-Tan, COE Community Health Liaison, Margaux Stack-Babich, MPH, Moores COE Manager, and Patty Maysent, Chief Executive Officer of UC San Diego Health.

Recent Community Engagement

On Sunday, January 19, COE attended the 43rd Annual Dr. Martin Luther King Jr. Parade on Harbor Drive to educate attendees on the importance of health and cancer prevention. Meanwhile, at the Borderview YMCA, COE Liaison Alexia Barrientos conducted a Cancer 101 that addressed cervical cancer, cancer awareness, early detection, and community resources. In addition, COE completed the LGBTQIA+ health needs assessment at the Lavender Welcome at MiraCosta College. COE not only thanks everyone who participated to help improve community health efforts, but also remains committed to promoting health equity, fostering community engagement, and addressing the unique needs of the Moores catchment area.

CAREERS

 
  • Senior Laboratory Scientist - 133970
  • Clinical Research Coordinator II - 133989
  • Histology Research Associate - 133608

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3855 Health Sciences Drive, La Jolla, CA 92037

moorescancercenter.ucsd.edu

 

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