The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
Week of November 11
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By Basic Sciences department Biochemistry Cell and Developmental Biology- Consensus tissue domain detection in spatial omics data using multiplex image labeling with regional morphology (MILWRM). Communications Biology.
Harsimran Kaur*, Cody Heiser, Eliot McKinley, Lissa Ventura-Antunes, Coleman Harris, Joseph Roland, Melissa Farrow, Ellie Pingry, Martha Shrubsole, Jeffrey Spraggins, Robert Coffey, Ken Lau*, Simon Vandekar*.
- Data-driven nucleus subclassification on colon hematoxylin and eosin using style-transferred digital pathology. Journal of Medical Imaging.
Lucas Remedios*, Shunxing Bao, Ho Hin Lee, Leon Cai, Thomas Li, Ruining Deng, Nancy Newlin, Adam Saunders, Can Cui, Jia Li, Qi Liu, Ken Lau, Joseph Roland, Mary Kay Washington, Lori Coburn, Keith Wilson, Yuankai Huo, Bennett Landman.
Supported by the Advanced Computing Center for Research and Education research core.
Molecular Physiology and Biophysics- Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells (preprint). bioRxiv.
Nobelle Sakwe* (Meharry Medical College), Heather Beasley, Antentor Hinton Jr.
- HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression (preprint).
Research Square.
Celestine Wanjalla*, Laventa Obare, Samuel Bailin, Xiuqi Zhang, Kisyua Nthenge, Stephen Priest, Qi Liu, Lindsay Stolze, Quanhu Sheng, Rama Gangula, Madelaine Behrens, Kit Neikirk, Heather Beasley, Tyne Miller-Fleming, Ky’Era Actkins, Jordan Malone, Cassia Labeb, Alexander Gelbard, Mona Mashayekhi, Curtis Gabriel, Lana Olson, Angela Jones, Karen Beeri, Paxton Baker, Tzushan Yang, Alexander Bick, Annet Kirabo, Yan Su, Elizabeth Phillips, Simon Mallal, John Koethe, Tarek Absi, Antentor Hinton Jr.
- Microvascular insulin resistance with enhanced muscle glucose disposal in CD36 deficiency. Diabetologia.
Cyndya Shibao*, Ian Williams, Naji Abumrad, Eric Gamazon, David Wasserman.
- Modeling Protein Conformations by Guiding AlphaFold2 with Distance Distributions. Application to Double Electron Electron Resonance (DEER) Spectroscopy (preprint). bioRxiv.
Tianqi Wu*, Richard A. Stein, Te-Yu Kao, Benjamin Brown, Hassane Mchaourab*.
Pharmacology- A nanobody toolbox for recognizing distinct epitopes on Cas9. Journal of Molecular Biology.
Jack Boylan*, Rebecca Shrem, Isabel Vallecillo-Viejo, Craig Duvall, Brian Wadzinski, Benjamin Spiller*.
Supported by the Vanderbilt Antibody and Protein Resource research core.
- Medicinal Chemistry Education and Training. Journal of Medicinal Chemistry.
Craig Lindsley.
- Medicinal Chemistry Education: Emphasize Fundamentals and Skillfully Integrate Knowledge. Journal of Medicinal Chemistry.
Shaoqing Du (Shandong University), Craig Lindsley*.
- Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate. ACS Chemical Neuroscience.
Julie Engers, Katrina Bollinger, Rory Capstick, Madeline Long, Aaron Bender, Jonathan Dickerson, Weimin Peng, Christopher Presley, Hyekyung Cho, Alice Rodriguez, Colleen Niswender, Sean Moran, Zixiu Xiang, Anna Blobaum, Olivier Boutaud, Jerri Rook, Darren Engers, P. Jeffrey Conn, Craig Lindsley.
Supported by the Laboratory for Neurobehavior research core.
MedicalXpress: Q&A: Designing a backup for a drug compound to improve memory loss in people with Alzheimer’s disease
- Seasonality in mood disorders: Probing association of accelerometer-derived physical activity with daylength and solar insolation. PLOS Mental Health.
Oleg Kovtun, Sandra Rosenthal.
College of Arts and Science: New study sheds light on seasonality in mood disorders
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Other basic biomedical papers
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First or corresponding authors are identified with a *. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.
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