Vanderbilt University | School of Medicine – Basic Science

“The Reading List” in dark teal with a drawing, in gold tones, of a person with long hair, sitting cross legged and reading a book.

First or corresponding authors are identified with an asterisk. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.

Week of May 13

By Basic Sciences department

Biochemistry

Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states (preprint). bioRxiv.
Brian MacTavish (The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology), Qianzhen Shao, Zhongyue Yang, Douglas Kojetin*.
Multidimensional mass profiles increase confidence in bacterial identification when using low-resolution mass spectrometers. Analyst.
Zachary Sasiene* (Los Alamos National Laboratory), Nathan Patterson, Martin Dufresne, Melissa Farrow, Jeremy Norris, Richard Caprioli.

Cell and Developmental Biology

The Hallmarks of Precancer. Cancer Discovery.
Mary Stangis* (University of Wisconsin-Madison), Zhengyi Chen*, Jimin Min* (University of Texas MD Anderson Cancer Center), Sarah Glass, Jordan Jackson* (University of Washington), Megan Radyk* (University of Michigan Medical School), Robert Coffey, Martha Shrubsole, Ken Lau*.

Highlighted on the Basic Sciences website.
Validation of an Organ Mapping Antibody Panel for Cyclical Immunofluorescence Microscopy on Normal Human Kidneys. American Journal of Physiology-Renal Physiology.
Maya Brewer*, Kelly Clouthier, Jamie Allen, David Anderson, Ellie Pingry, Melissa Farrow, Jeffrey Spraggins, Raf Van de Plas, Mark de Caestecker*.

Molecular Physiology and Biophysics

The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults. eLife.
Arya Nakhe*, Prasanna Dadi, Jinsun Kim, Matthew Dickerson, Soma Behera, Jordyn Dobson, Shristi Shrestha, Jean-Philippe Cartailler, Leesa Sampson, Mark Magnuson, David Jacobson*.
Adiposity, immunity, and inflammation: interrelationships in health and disease: A report from 24th annual Harvard nutrition obesity symposium, June 2023. The American Journal of Clinical Nutrition.
M Furkan Burak* (Harvard Medical School), Alyssa Hasty.
Salt Sensitivity of Blood Pressure. Circulation Research.
Jeremiah Afolabi*, Cheryl Laffer, Heather Beasley, Antentor Hinton Jr., Annet Kirabo*.

Pharmacology

Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Journal of Chemical Theory and Computation.
Benjamin Brown*, Richard Stein, Jens Meiler*, Hassane Mchaourab*.

Highlighted on the Basic Sciences website.
Immunoproteasomal Processing of IsoLG-Adducted Proteins Is Essential for Hypertension. Circulation Research.
Néstor de la Visitación*, Wei Chen, Jaya Krishnan, Justin Van Beusecum, Venkataraman Amarnath, Elizabeth Hennen, Shilin Zhao, Mohammad Saleem, Mingfang Ao, Sergey Dikalov, Anna Dikalova, David Harrison, David Patrick*.

Other basic biomedical papers

Synthesis and Evaluation of a Novel PET Radioligand for Imaging Glutaminyl Cyclase Activity as a Biomarker for Detecting Alzheimer’s Disease. ACS Sensors.
William Behof*, Justin Haynes, Clayton Whitmore, Yiu-Yin Cheung, Mohammed Tantawy, Todd Peterson, Printha Wijesinghe, Joanne Matsubara, Wellington Pham*.

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Vanderbilt University School of Medicine Basic Sciences
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Phone: (615) 322-0907 | basicsciences@vanderbilt.edu

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