The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
Week of May 5
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School of Medicine Basic Sciences departmentsBiochemistry Molecular Physiology and Biophysics- Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster (preprint). bioRxiv.
David Hubert* (Oregon State University), Zer Vue, Antentor Hinton Jr.
- 3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN-2-Mediated Changes. Aging Cell.
Estevão Scudese*, Andrea Marshall, Zer Vue, Benjamin Rodriguez, Mert Demirci, Larry Vang, Kit Neikirk, Bryanna Shao, Han Le, Dominique Stephens, Taylor Rodman, Kinuthia Kabugi, Margaret Mungai, Sasha Manus, Celestine Wanjalla, Aaron Whiteside, Jennifer Gaddy, Annet Kirabo, Sepiso Masenga, Ashton Oliver, Bret Mobley, Antentor Hinton Jr.*
Pharmacology
- Resistance and resilience to Alzheimer's disease in Down syndrome. Alzheimer’s & Dementia.
Rory Boyle* (University of Pennsylvania), Alexander Conley, Paul Newhouse, Jason Russell, Jo Ellen Wilson.
- Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5. ACS Medicinal Chemistry Letters.
Katherine Crocker*, Scott Henderson, Rory Capstick, David Whomble, Aaron Bender, Andrew Felts, Changho Han, Julie Engers, Natasha Billard, Mallory Maurer, Hyekyung Cho, Alice Rodriguez, Colleen Niswender, Jordan O'Neill, Katherine Watson, Sichen Chang, Anna Blobaum, Olivier Boutaud, Weimin Peng, Jerri Rook, P Jeffrey Conn, Craig Lindsley, Kayla Temple*.
- Structural basis for regulation of CELSR1 by a compact module in its extracellular region. Nature Communications.
Sumit Bandekar* (The University of Chicago), Krassimira Garbett, Tanner Shearer, Richard Sando*.
- Proteostasis landscapes of cystic fibrosis variants reveal drug response vulnerability. Proceedings of the National Academy of Sciences.
Eli Fritz McDonald*, Minsoo Kim, John Olson III, Jens Meiler*, Lars Plate*.
Supported by the Mass Spectrometry Research Center.
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First or corresponding authors are identified with an *. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.
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