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Revolutionizing healthcare by advancing the frontiers of technology

What if your doctor could check in on your health every day—without you ever stepping foot in a clinic? A smartwatch streaming data into a digital twin of your body flagging changes before you notice symptoms, enabling proactive, personalized care. Surgeons rehearsing your exact procedure in virtual reality, while AI models recommend the treatments most likely to succeed.

This isn’t science fiction. It’s the future of healthcare—and it’s the future our Center is building.

At the intersection of high performance computing, AI, extended reality, and wearable technologies, we are advancing tools that can find disease earlier, track it continuously, and treat it more precisely. By developing patient-specific digital twins, we make continuous, remote, and non-invasive monitoring possible. By leveraging wearable sensors, we capture streams of real-world data that fuel those twins and extend care beyond the clinic walls. By applying AI, we uncover hidden patterns in that data and generate predictive insights to guide truly personalized treatment. By creating immersive XR platforms, we make complex information intuitive and unlock new possibilities in rehabilitation and patient engagement. Together, these technologies are converging to transform medicine from reactive to proactive care.

In this inaugural issue, we’re excited to share:

  • A new certificate program offering interdisciplinary training in computational modeling, AI, wearable sensors, and digital twins—all grounded in bioethics and clinical translation.
  • New Associate Directors who will help expand and strengthen our research and education missions.
  • Fall events, including our Virtual Seminar series and the launch of Espresso Chats—informal, 30-minute conversations connecting students with alumni, industry leaders, and innovators in digital health.

The Center was established to connect people, share ideas, and spark the collaborations that will extend the frontiers of health. Rooted in engineering, we bring together diverse expertise to improve healthspan through cutting-edge technologies. We’re thrilled to share this journey with you—and this is just the beginning.

Amanda Randles, Ph.D.
Director, Center for Computational and Digital Health Innovation

Learn More About the Center

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Upcoming Events

John Hickey

From Code to Cell: Bridging Spatial Omics, Machine Learning, and Cell Engineering

September 4 @ 3:00 pm - 4:00 pm

Speaker: John Hickey

Jeff Hammond

Espresso Chat: Jeff Hammond from NVIDIA

September 11 @ 9:00 am - 9:30 am

Michael Rubenstein

The Loops of Life

November 6 @ 3:00 pm - 4:00 pm

Speaker: Michael Rubinstein

More events
 

Recent Blog Posts

Person's face with a digital version next to it

Digital Twins in Healthcare: Revolutionizing Patient Care at Duke

Digital twin technology is transforming industries by creating precise virtual replicas of physical systems—and I’ve seen how its application in healthcare can revolutionize patient care.

Wearables in Action: Transforming Patient Care Through Proactive Health Monitoring

We're exploring how wearables will redefine healthcare, making continuous monitoring the new standard.

Smart watch on a wrist
Hand of a person interacting with augmented reality

Extended Reality in Action at Duke: Immersive Technology in Real-World Medicine

Extended reality is already reshaping industries of all kinds—but its most life-changing impact may be in healthcare. 

Awards and Honors

  • Cameron Kim Receives ASEE Biomedical Engineering Teaching Award
  • Hickey Receives NSF CAREER Award to Study How Environmental Factors Drive Cellular Behavior
  • Jessilyn Dunn Wins EMBS Early Career Achievement Award
  • Center Members Win Award at ICCS25
  • Boyuan Chen Named to ASME Mechanical Engineering Magazine Watch List
  • Hickey Receives Young Investigator Grant to Support International Research Collaboration
  • Neurosurgeon David Hasan Honored at AANS Annual Meeting
  • Juliet Jiang Receives NSF Graduate Research Fellowship Program Award
  • Hasan Elected Fellow of the American Association for the Advancement of Science
  • Amanda Randles Named to HPCwire 2025 People to Watch
 

Publications

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WatchSleepNet: A Novel Model and Pretraining Approach for Advancing Sleep Staging with Smartwatches

Proceedings of Machine Learning Research

Nursing Outlook cover

Physical Artificial Intelligence in Nursing: Robotics

Nursing Outlook

Mechanics of Materials cover

Enhancing Robustness in Machine-Learning-accelerated Molecular Dynamics: A Multi-model Nonparametric Probabilistic Approach

Mechanics of Materials

Microfluidic Digital Twin for Enhanced Single-Cell Analysis

Computational Science – ICCS 2025

More publications

Featured News

Amanda Randles

Amanda Randles: A Check-Engine Light for the Heart

Center Director Amanda Randles talks about how she brought together early interests in physics, coding, biomedicine and even political science and policy. 

Jessilyn Dunn

Medical Insights, Now Available on Your Wrist

Jessilyn Dunn gathers biometric data from smartwatches to study and predict health changes. 

Cameron Kim speaking to students

Engineering with Character: Cameron Kim on Intellectual Curiosity and Humility

As part of Duke Engineering’s Character Forward initiative, Cameron Kim discusses how he integrates character development into technical education

Montage of students who presented at GWDD

Pushing the Boundaries of Biomedical Innovation – Center Students Present at GWDD

We proudly celebrated several undergraduate researchers presenting their Graduation with Departmental Distinction (GWDD) posters in Biomedical Engineering.

More news
 

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Duke Center for Computational and Digital Health Innovation
Duke University
Durham, NC 27708

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