The Reading List is a newsletter from the School of Medicine Basic Sciences in which we amplify biomedical research from our four departments and campus-wide collaborators.
Week of March 31
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School of Medicine Basic Sciences departments Biochemistry Cell and Developmental Biology- Characterization and comparison of Schizosaccharomyces pombe cdc15 temperature-sensitive mutants. microPublication Biology.
Lesley Turner*, Alaina Willet, Kathleen Gould*.
- Solid-State NMR Analysis of Schizosaccharomyces pombe Reveals Role of α-Amylase Family Enzymes in Cell Wall Structure and Function (preprint). bioRxiv.
Anand Jacob* (Michigan State University), Alaina Willet, Maya Igarashi, Lesley Turner, Kathleen Gould*.
- Characterization of temperature-sensitive alleles of anillin-like Mid1 and polo kinase Plo1 in Schizosaccharomyces pombe. microPublication Biology.
Joshua Park*, Lesley Turner, Kathleen Gould, Alaina Willet*.
- Leptomeningeal Neural Organoid Fusions as Models to Study Meninges-Brain Signaling. Stem Cells and Development.
Hannah Jones* (University of Colorado Anschutz Medical Campus), Gabriella Robertson, Caroline Bodnya, Alejandra Romero-Morales, Vivian Gama*.
- Tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer. Developmental Cell.
Daniel Salas-Escabillas* (University of Michigan), Kathleen DelGiorno.
- Distinct type 1 immune networks underlie the severity of restrictive lung disease after COVID-19. Nature Immunology.
Glenda Canderan* (University of Virginia School of Medicine), Lyndsey Muehling* (University of Virginia School of Medicine), Claire Cross, Sierra Lima, Jonathan Irish.
Molecular Physiology and Biophysics- 10°C static storage of porcine donation after circulatory death livers improves biliary viability and mitigates ischemia reperfusion injury. American Journal of Transplantation.
Kaitlyn Tracy*, Yutaka Shishido, Mark Petrovic, TiOluwanimi Adesanya, Avery Fortier, Timothy Harris, Michael Cortelli, William Tucker, Sean François, Brandon Petree, Kimya Raietparvar, Victoria Simon, Carl Johnson Jr., Elizabeth Simonds, John Poland, Gabriella Glomp, Christian Crannell, Jiancong Liang, Andrea Marshall, Antentor Hinton Jr., Ciara Shaver, Caitlin Demarest, Rei Ukita, Ashish Shah, Michael Rizzari, Martin Montenovo, M. Ameen Rauf, Matthew Bacchetta.
Supported by the Vanderbilt Cell Imaging Shared Resource.
Pharmacology- DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer. Molecular Cancer.
Benjamin Morris* (The University of Texas MD Anderson Cancer Center), Darren Tyson, Vito Quaranta.
- Application of Deuterium in an M1 Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422. ACS Chemical Neuroscience.
Julie Engers*, Jinming Li, Changho Han, Madeline Long, Alison Gregro, Christopher Presley, Jonathan Dickerson, Weimin Peng, Hyekyung Cho, Alice Rodriguez, Zixiu Xiang, Olivier Boutaud, Colleen Niswender, Jerri Rook, P. Jeffrey Conn, Darren Engers, Craig Lindsley*.
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Other biomedical research papers- Running a genetic stop sign accelerates oxygen metabolism and energy production in horses. Science.
Gianni Castiglione*, Xin Chen, Nadir Dbouk, Anamika Bose, David Carmona-Berrio, Emiliana Chi, David Rinker, Antonis Rokas.
“The gene and resulting protein at the center of the adaptation isn’t just for horses—it also has serious clinical implications for health research. It’s possible that, by uncovering the mystery of horse athleticism, scientists could find new treatments for neurodegenerative diseases in humans like Alzheimer’s or even therapies to stall the declines of normal aging,” Lauren Leffer, Popular Science.
Popular Science: Scientists discover why horses are such exceptional athletes
NPR: A new study reveals the genetic change that made horses so athletic
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First or corresponding authors are identified with an *. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.
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