Recently Published

• Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry.
  Pradeep Pallan, Terry Lybrand, Martin Egli.
  
  
• 25 Years of PI5P. Frontiers in Cell and Developmental Biology.
  Lucia Plant, Raymond Blind.
  
  
• SF-1 Induces Nuclear PIP2. Biomolecules.
  Ethan Chi, Elizabeth Stivison, Raymond Blind.
  
  
• Loss of p73 Expression Contributes to Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine.
  Bradley Richmond, Clayton Marshall, Jessica Blackburn, Tiffany Tufenkjian, Brian Lehmann, Wei Han, Dawn Newcomb, Sergey Gutor, Raphael Hunt, Danielle Michell, Kasey Vickers, Vasiliy Polosukhin, Timothy Blackwell, Jennifer Pietenpol.
  
  
• Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp. eLife.
  Abigail Neininger-Castro, James Hayes, Zachary Sanchez, Nilay Taneja, Aidan Fenix, Dylan Burnette.
  
  
• Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells. Proteomics.
  Lizandra Jimenez, Victor Stolzenbach, Patricia Ozawa, Marisol Ramirez-Solano, Qi Liu, Alissa Weaver.
  
  
• Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A. Proteomics.
  Bahnisikha Barman, Marisol Ramirez, Toni Renee Dawson, Qi Liu, Alissa Weaver.
  
  
• Effects of KRAS genetic interactions on outcomes in cancers of the lung, pancreas, and colorectum. Cancer Epidemiology, Biomarkers & Prevention.
  Isabella Grabski (Harvard), Ken Lau.
  
  
• Editorial: The role of macrophages in metabolic disorders. Frontiers in Physicology.
  Yagna Jarajapu (North Dakota State University), Alyssa Hasty.
  
  
• Protocol for isolating mice skeletal muscle myoblasts and myotubes via differential antibody validation. STAR Protocols.
  Dominique Stephens, Margaret Mungai (University of Iowa), Amber Crabtree, Heather Beasley, Larry Vang, Kit Neikirk, Zer Vue, Neng Vue, Andrea Marshall, Jennifer Gaddy, Antentor Hinton Jr.
  
  
• Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nature Communications.
  Qingyu Tang, Matt Sinclair (University of Illinois Urbana-Champaign), Hale Hasdemir, Richard Stein, Erkan Karakas, Hassane Mchaourab.
  
  
• Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of raptor and this contributes to the weight loss effect of liraglutide. eLife.
  Thao Le, Dianxin Liu, Gai-Linn Besing, Ritika Raghavan, Blair Ellis, Ryan Ceddia, Sheila Collins, Julio Ayala.
  
  
• Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice. Endocrinology and Metabolism.
  Curtis Hughey (University of Minnesota), Deanna Bracy, Mickael Goelzer, Patrick Donahue, David Wasserman.
  
  
• CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine. ACS Chemical Biology.
  Eli Fritz McDonald, Jens Meiler, Lars Plate.
  
  
• Interplay of thermodynamics and evolution within the ternary ligand-GPCR-G protein complex. Current Opinion in Structural Biology.
  Hannes Junker (University Leipzig), Jens Meiler.
  
  
• Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nature Communications.
  Valerie O’Donnell (Cardiff University), Ginger Milne, Alan Brash.
  
  
• Mutexa: A Computational Ecosystem for Intelligent Protein Engineering. Journal of Chemical Theory and Computation.
  Zhongyue Yang, Qianzhen Shao, Yaoyukun Jiang, Christopher Jurich, Xinchun Ran, Reecan Juarez, Bailu Yan, Sebastian Stull, Anvita Gollu, Ning Ding.
  
  
• Tumor-Reactive CD8+ T Cells Enter a TCF1+PD-1− Dysfunctional State. Cancer Immunology Research.
  Jessica Roetman, Megan Erwin, Michael Rudloff, Natalie Favret, Carlos Detrés Román, Minna Apostolova, Kristen Murray, Ting-Fang Lee, Youngmin Lee, Mary Philip.
  
  “[Jess Roetman] developed a unique cancer model in which we could study CD8 T cell responses against tumor-specific antigens and self/shared antigens,” Philip lab.
  

Highlighted across the web

• "Chasing Alzheimer’s with Blood and Artificial Intelligence."
  Emma Webb (Pharmacology, Heidi Hamm lab) is featured.
  
  
• "Opera meets neuroscience: Vanderbilt’s Lisa Monteggia discusses the science of Nashville Opera’s ‘The Man Who Mistook His Wife for a Hat’."
  Lisa Monteggia (Pharmacology) was featured in Vanderbilt Research News.
  
  
• SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes.Cell Reports Medicine.
  Steven Wall, Naveenchandra Suryadevara, Changil Kim, Andrea Shiakolas, Clinton Holt, Emma Irbe, Perry Wasdin, Yukthi Suresh, Elad Binshtein, Elaine Chen, Seth Zost, Elizabeth Canfield, James Crowe Jr., Mary Ann Thompson-Arildsen, Daniel Sheward, Robert Carnahan, Ivelin Georgiev.
  
  “A collaborative effort led by PhD candidate Steven Wall shows that [antibodies] from children exhibit broad [SARSCoV2] neutralization, including against highly resistant [virus] variants, but have similar sequence features compared to adults,” Ivelin Georgiev.
  
  Highlighted in the VUMC Reporter.
  
  
• "Generations of Chemistry."
  Steven Townsend (Chemistry) is featured in Vanderbilt's Quantum Potential.
  

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