It’s official: The pumpkin spice latte is flowing. We hope you had a great Halloween, have fully adjusted to the move back to standard time, and are looking forward to the winter holiday break.
In this issue:
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- Discover a major USC Dornsife advance in predicting teen anxiety.
- Find out how a flagship USC Dornsife program is going national.
- Learn why picking the right DNA blueprint is key to solid genetic research.
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See how Trojan excellence extends beyond the playing field.
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2 Brain Scans Spot Teen Anxiety Early |
USC Dornsife psychology researchers found that using two types of brain imaging can better predict which teens may develop significant anxiety years down the line.
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Why it matters: Finding risk earlier allows for timely, tailored support before anxiety takes hold.
How they did it: Brain scans from teens in a study that began in infancy were examined.
The big picture: Each scan type captures a different slice of brain function, and together they give a fuller read.
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- Used alone, each had limited predictive power, but fusing them improved forecasting of future anxiety.
- EEG shows when brain activity happens; fMRI shows where it happens.
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By the numbers: The combined brain signals offered real predictive power, not just statistical noise.
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- The fused EEG-fMRI data explained about 25% of changes in teens’ anxiety between ages 13 and 15.
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The goal: Determine which kids might benefit from support before anxiety becomes a lifelong issue by reading the brain’s early signals.
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What’s next: The team, led by Assistant Professor Emilio Valadez, plans to test if similar prediction models work even earlier — in children aged 8 to 9 — and to explore other brain functions (memory, attention, etc.) to sharpen forecasts.
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USC Dornsife Expands Eastward |
Public Exchange (PX), USC Dornsife’s initiative connecting academic expertise with cities, nonprofits, private companies and others, is expanding to Washington University in St. Louis — its first university partner outside USC.
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WashU will adopt PX’s model to speed collaborations between researchers and public agencies in their area.
- The move signals rising demand for fast, evidence-based solutions to real-world problems.
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Why it matters: The expansion shows how the PX model can scale nationally to help governments and communities act on research more quickly.
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- It also marks the first step in PX’s broader plan to bring its model to institutions nationwide.
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The big picture: PX launched at USC Dornsife in 2020 to connect decision-makers with scholars capable of rapid, applied research.
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The platform has delivered insights on climate, homelessness, public health and economic mobility.
- Its approach cuts the time it takes to form research partnerships from months — or even years — to day.
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What they’re saying: “Public Exchange provides a framework that allows faculty and researchers in the liberal arts and other fields to bring value to their communities and lean into one of the core purposes of institutions like ours: to improve lives and livelihoods through education, research and service,” said USC Dornsife Dean James Bullock.
USC Dornsife plans to continue expanding Public Exchange to more universities and government partners, building a national network that puts research to work quickly for communities.
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Quantum Takes Center Stage at USC |
What happens when scientists, CEOs and lawmakers all agree on something? At USC’s Quantum Technologies Forum, they found common cause in a field that could reshape medicine, security and the economy — and it’s all happening right here in Los Angeles.
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Pro-tip! Pick the Right DNA Blueprint |
Professor Jazlyn Mooney has found that referencing a closely related species’ genome rather than one from the same species can distort genetic research results — sometimes by as much as 60%.
The big picture: Many species lack their own reference genome, so scientists use the next best available, which can seriously skew findings.
Why it matters: Wrong genetic maps may lead conservationists to protect the wrong populations or miss real threats altogether.
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The wrong blueprint also incorrectly flags twice as many genome regions that look like they might be important to adaptation, giving a false picture of the fox’s ability to evolve as its environment changes.
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By the numbers: Using the actual gray fox genome for research, instead of one from a dog or Arctic-fox, revealed up to 32% more genetic differences and about one-third more rare variants.
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- Population size estimates were 30% to 60% higher than when using mismatched references. Alarmingly, the common practice of aligning it with the dog or Arctic fox genome made populations appear to be declining when, in fact, they were stable or growing.
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Mismatched references also doubled or tripled error rates in key genetic measures.
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In her words: “It turns out the reference you use really changes the story you tell about a species,” Mooney said. “If you use the wrong reference, you can end up with misleading answers about a species’ history or health, and even its chances of long-term survival.”
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What’s next: The researchers call for greater investment in high-quality, species-specific genomes and new computational methods.
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Renowned primatologist Jane Goodall left an inspiring legacy at USC Dornsife. Go Deeper >>
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Spatial sciences professor wins Nobel Sustainability Trust Award. Go Deeper >>
- Researchers invent AI tool to automate cancer detection in blood samples. Go Deeper >>
- USC Dornsife honors 104-year-old alumnus, veteran and former Secretary of the Navy. Go Deeper >>
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Excellence In and Out of the Arena |
Trojans have made their mark in the arena for more than a century. We’ve also been driving research that changes the worlds.
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Meet USC Dornsife’s 23rd Dean |
James Bullock shares his vision for the College and how a liberal arts education will prepare students for an unpredictable world.
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| The Pilgrims’ survival hinged on unexpected events and overlooked alliances — including a little-known chapter of Indigenous history that shaped their first winter in the “new world.”
The surprising truth is revealed in this fascinating story by historian and Distinguished Professor Peter Mancall.
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Opportunity: USC Compass Program |
Sophomores of all academic backgrounds are invited to join an upcoming information session for the two-year USC COMPASS Program, which prepares students for careers in stem cell biology and regenerative medicine. The program includes a academic year and summer research stipends, tuition remission, and personalized career coaching!
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Nominate a Communicator of the Year |
The awards honor scholars from USC Dornsife who engage with the public to improve its understanding of issues, influence policy and/or raise the level of public discourse!
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Self-nominations are welcome.
- Open to every faculty member, researcher, center/institute leader and currently enrolled PhD student whose primary affiliation is with USC Dornsife.
- Winners will be selected based on the activities they have engaged in during calendar year 2024 to share their expertise.
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Nomination Deadline: Dec. 22.
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 | Nov. 20, 2 - 3 p.m. PT |
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 | Social Sciences Building |
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Join a mock interview workshop for students offering tips and advice for success. Students or community members interested in attending should register.
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2 Hours with Chinese Kunqu Opera |
 | Nov. 21, 10:30 a.m. - 12:30 p.m. PT |
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 | Doheny Memorial Library |
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Attend a performance and guest lecture by Fang Wei and her team from the Kunqu Opera Society USA, including a live performance from two classic Kunqu pieces and an introduction to the tradition.
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| Renaissance Christmas Music |
 | Dec. 7, 2 p.m. PT |
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 | Mission San Gabriel Arcángel |
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The USC-Huntington Early Modern Studies Institute Music Series invites you to join them for a free concert, “Renaissance Music from Saint Nicholas to Christmas.”
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Cosmic Conversation. Students in freshman “Physics Discovery Series” (PHYS 190) enjoyed a visit from USC Dornsife Dean James Bullock, an accomplished cosmologist, who spoke with instructor Kris Pardo, assistant professor of physics and astronomy, and the class in a podcast-style format. Bullock then stayed after the bell to chat with the first-year physics majors. (Photo: Vaidik Vadhavana/El Rodeo.)
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