Human immunodeficiency virus (HIV) and substance use disorders (SUD) represent a significant public health syndemic. A syndemic occurs when two or more health conditions interact and reinforce one another, causing a synergistic negative effect (HHS, 2024). This syndemic is especially prevalent for men who have sex with men (MSM), a population who experience disproportionate rates of HIV and elevated prevalence of substance use (Bourne et al, 2017, HHS, 2026). According to federal health data, 89% of all new HIV diagnoses are transmitted via sexual contact, with the most common route being unprotected vaginal or anal sex (HHS, 2025). When substances are involved before or during sexual activity, the risk of HIV transmission increases.