M4 Positive Allosteric Modulator VU0467154 Impacts Amphetamine Sensitization and Spontaneous Locomotion in Male Mice. ACS Chemical Neuroscience
Berezovskaia A, Lindsley C, Fink-Jensen A, Wörtwein G.
Discovery of ONO-2920632 (VU6011887): A Highly Selective and CNS Penetrant TREK-2 (TWIK-Related K+ Channel 2) Preferring Activator In Vivo Tool Compound. ACS Chemical Neuroscience
Yashiro K, Iwaki Y, Urata H, Kokubo M, Mori T, Sekioka Y, Isami K, Kato J, Wieting J, McGowan KM, Bridges TM, Boutaud O, Engers DW, Denton JS, Kurata H, Lindsley CW.
Cryo-EM reveals a new allosteric binding site at the M5 mAChR. bioRxiv
Burger WAC, Mobbs JI, Rana B, Wang J, Joshi K, Gentry PR, Yeasmin M, Venugopal H, Bender AM, Lindsley CW, Miao Y, Christopoulos A, Valant C, Thal DM.
Shank3 modulates Rpl3 expression and protein synthesis via mGlu5: implications for Phelan McDermid syndrome. Molecular Psychiatry
Federica Giona, Stefania Beretta, Antonio Zippo, Alessia Stefanoni, Zaira Tomasoni, Cinzia Vicidomini, Luisa Ponzoni, Mariaelvina Sala, Carrie K Jones, P Jeffrey Conn, Tobias M Boeckers, Carlo Sala, Chiara Verpelli
Application of Deuterium in an M1 Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422. ACS Chemical Neuroscience
Julie L. Engers, Jinming Li, Changho Han, Madeline F. Long, Alison R. Gregro, Christopher C. Presley, Jonathan W. Dickerson, Weimin Peng, Hyekyung P. Cho, Alice L. Rodriguez, Zixiu Xiang, Olivier Boutaud, Colin O’Carroll, P. Markus Dey, Ethan S. Burstein, Colleen M. Niswender, Jerri M. Rook, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley.
