Department Quarterly Newsletter: April 2023
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Welcome New Staff and Trainees
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Pavle Boskovic, Postdoc Research Associate (Kipnis Lab)
Joe Bova, Grant Specialist II (Research Admin Team)
Ann Chaffee, Pathologist Assistant (Perrin Lab)
Andrew Csepp, Senior Clinical Laboratory Technician (Cytogenetics Lab)
Christine Gatuiria, Research Administrator (Research Admin Team)
Susan Keen, Administrative Assistant I (Gutierrez Admin Team)
Intelly Lee, MD, PhD, Rheumatology Fellow (Van Dyken Lab)
Keandra Long, Senior Grants Specialist (Research Admin Team)
Will McElhenney, Bioinformaticist (Zaydman Lab)
Ruth Munoz, Certified Coder (Revenue Cycle Team)
Riley Nadler, Research Technician II (Watson Lab )
Deanna Pino, Administrative Assistant II (Gutierrez Admin Team)
Hannah Powell, Research Technician II (Corbo Lab)
Alexey Prokudin, Bioinformatics Research Assistant (Despotis Lab)
Monika Shukla, Staff Scientist (Jain Lab)
Maria Turnbough, Coordinator Education (Education Team)
Kevin Wade, Clinical Laboratory Technologist II (Yarbough Lab)
Anelia Wise, Genetic Counseling Assistant (Cortex Genomics Team)
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Dr. Eynav Klechevsky publishes paper on patient response to cancer immunotherapy |
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Eynav Klechevsky, PhD, Assistant Professor of Pathology & Immunology in the Department of Pathology & Immunology at Washington University School of Medicine, is senior author on a Science paper that helps explain why some cancer patients do not respond to immunotherapy. The findings suggest that a supplementary therapy designed to increase the number or activity of CD5+ dendritic cells potentially could extend the lifesaving benefits of immunotherapy to more cancer patients.
Read the full press release from Washington University School of Medicine.
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WUSM research team including Dr. Maxim N. Artyomov discover T cells' role in Alzheimer's |
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A new study from researchers at Washington University School of Medicine in St. Louis including Maxim N. Artyomov, PhD, Alumni Endowed Professor, Pathology & Immunology, indicates that microglia partner with another type of immune cell--T cells--to cause neurodegeneration. The findings could pave the way for new treatments Alzheimer’s disease and related conditions.
Read the full story from Washington University School of Medicine.
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Dr. Robert Schreiber receives AACR Lectureship |
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Robert Schreiber, PhD, FAACR, Andrew M. and Jane M. Bursky Distinguished Professor of Pathology & Immunology at Washington University School of Medicine, has received the American Association for Cancer Research (AACR) Princess Takamatsu Memorial Lectureship. The lectureship “recognizes an individual scientist whose novel and significant work has had or may have a far-reaching impact on the detection, diagnosis, treatment, or prevention of cancer,” AACR said in a statement.
Read the full story on the Pathology & Immunology website.
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Dr. Sonika Dahiya named to Working Committee of cIMPACT-NOW |
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Sonika Dahiya, MD, Professor of Pathology & Immunology in the Department of Pathology & Immunology at Washington University School of Medicine, was recently named to the Working Committee of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW). The consortium was established under the sponsorship of the International Society of Neuropathology (ISN) in late 2016 to provide a forum to evaluate and recommend proposed changes to future CNS tumor classifications.
Read the full story on the Department of Pathology & Immunology website.
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Dr. Erika Crouch receives Diversity Distinguished Service Teaching Award
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Erika Crouch, MD, PhD, Professor of Pathology & Immunology and Vice Chair of the Office of Education at Washington University School of Medicine, has received the Diversity Distinguished Service Teaching Award. The award, which honors Dr. Crouch’s teaching in the 2021-2022 academic year, is from the Washington University School of Medicine entering class of 2021. “What could be better for an educator than being recognized by one’s students? Not much!” Dr. Crouch said.
Read the full story on the Pathology & Immunology website.
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Dr. Gwen Randolph receives Outstanding Faculty Award |
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Gwen Randolph, PhD, Emil R. Unanue Professor of Pathology & Immunology, has received an Outstanding Faculty Award from the Graduate Student Senate at Washington University in St. Louis. “This award means a lot to me. Realizing that I have helped make a positive difference in the educational experiences and lives of students is an incredible thing. It is what we are meant to do as mentors and leaders,” Dr. Randolph said.
Read the full story on the Pathology & Immunology website.
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ChromoSeq gains Medicare approval |
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ChromoSeq, an advanced diagnostic assay developed in the Department of Pathology & Immunology, was recently approved for reimbursement by The Centers for Medicare & Medicaid Services (CMS). The test is based on whole genome sequencing (WGS) that provides a comprehensive genomic assessment of newly diagnosed patients with AML and MDS. ChromoSeq was developed by Eric Duncavage, MD, Molly Schroeder, PhD, and David Spencer, MD, PhD.
Read the full story on the Department of Pathology & Immunology website.
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Dr. Stephen Persaud named 2023 ASH Scholar |
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Stephen Persaud, MD, PhD, Instructor of Pathology & Immunology in the Department of Pathology & Immunology at Washington University School of Medicine, was recently named an American Society of Hematology (ASH) Scholar for 2023. One of ASH’s most prestigious research award programs, the ASH Scholar Awards support early career investigators dedicated to careers in hematology research as they transition from training programs to careers as independent investigators.
Read the full story on the Department of Pathology & Immunology website.
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Dr. Liang-I Kang receives K12 Paul Calabresi Career Development Award in Clinical Oncology |
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Liang-I Kang, MD, PhD, Instructor of Anatomic and Molecular Pathology in the Department of Pathology & Immunology at Washington University School of Medicine, has received a K12 Paul Calabresi Career Development Award in Clinical Oncology from NIH’s National Cancer Institute (NCI). Dr. Kang, an alumni of the department’s Physician Scientist Training Program (PSTP), was promoted to full-time instructor effective March 1 as part of accepting the award.
Read the full story on the Department of Pathology & Immunology website.
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Dr. Nicholas Borcherding receives ASCI 2023 Emerging Generation Award |
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Nicholas Borcherding, MD, PhD, resident in Clinical Pathology and a member of the Physician Science Training Program (PSTP) in the Department of Pathology & Immunology at Washington University School of Medicine, recently received a 2023 Emerging Generation Award from The American Society for Clinical Investigation (ASCI). The award recognizes post-MD, pre-faculty appointment physician-scientists who are meaningfully engaged in immersive research.
Read the full story on the Department of Pathology & Immunology website.
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Two P&I MSTP students selected as Olin Fellows |
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Vincent Peng, an MD/PhD student in the Colonna Lab in the Department of Pathology & Immunology at Washington University School of Medicine, and Renee Wu, an MD/PhD student in the Murphy Lab in the Department of Pathology & Immunology at Washington University School of Medicine, were recently selected as Olin Fellows. Olin Fellowships are presented to PhD and MD/PhD students conducting research in the biomedical sciences in any Washington University graduate program who have made significant contributions and demonstrated the potential to become outstanding research scientists.
Read the full story on the Department of Pathology & Immunology website.
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Kipnis Lab graduate student passes thesis defense |
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Andrea Francesca Salvador, PhD, a graduate student in the Kipnis Lab, successfully defended her thesis on April 27, 2023. Dr. Salvador's talk was entitled, "Age-dependent immune and lymphatic responses after spinal cord injury." Her work on spinal cord injury was recently accepted in Neuron and will be in print later this year.
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Pooja Khonde, Elizabeth Brunt, et. al. Liver pathology in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: vasculopathic disease beyond nodular regenerative hyperplasia. Human Pathology, May 2023. Article
Kaleigh Roberts, et. al. Diffusion basis spectrum imaging as an adjunct to conventional MRI leads to earlier diagnosis of high-grade glioma tumor progression versus treatment effect. Neuro-Oncology Advances, April 2023. Article
Ronald Jackups, Jr. FDA Regulation of Laboratory Clinical Decision Support Software: Is It a Medical Device? Clinical Chemistry, April 2023. Article
Marco Colonna, Tom Hannan, et. al. Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome. Nature Microbiology, April 10, 2023. Article
Steffen Storck, Taitea Dykstra, Siling Du, Igor Smirnov, Jonathan Kipnis, et. al. Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage. Journal of Experimental Medicine, April 7 2023. Article
Reza Ghasemi, Eric Duncavage, David Spencer, et. al. Persistent Molecular Disease in Adult Patients With AML Evaluated With Whole-Exome and Targeted Error-Corrected DNA Sequencing. JCO Precision Oncology, April 2023. Article
Sameer Kumar Malladi, Jackson Turner, Ali Ellebedy, et. al. SARS-CoV-2 Omicron boosting induces de novo B cell response in humans. Nature, April 3, 2023. Article
Jinchao Hou, Yingyue Zhou, Susan Gilfillan, Do-Hyun Kim, Steven J. Van Dyken, Maxim N. Artyomov,
Marco Colonna, et. al. Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination. Cell Reports, March 21, 2023. Article
Patricia V. Hernandez, Meagan M. Corliss, Molly C. Schroeder, Jonathan W. Heusel, Julie A. Neidich, Yang Cao, et. al. High-depth next-generation sequencing panel testing in the evaluation of arteriovenous malformations. American Journal of Medical Genetics, March 16, 2023. Article
Joseph P. Gaut. Time to Abandon Renalism: Patients with Kidney Diseases Deserve More. Clinical Journal of the American Society of Nephrology, March 9, 2023. Article
Molly Schroeder, John SA Chrisinger, et. al. Molecular Characterization of Multifocal Granular Cell Tumors. The American Journal of Surgical Pathology, March 2023. Article
Carey-Ann D. Burnham, Gautam Dantas, et. al. Outpatient Clonal Propagation and Rapid Regional Establishment of an Emergent Carbapenem-Resistant Acinetobacter baumannnii Lineage Sequence Type 499. The Journal of Infectious Diseases, March 2023. Article
Eric Duncavage, et. al. Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Blood, November 2022. Article.
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Marco Colonna, MD, Tom Hannan, DVM, PhD
$3.1 million, multi-year award from NIH for “Mucosal Immune Defense Mechanisms of the Urinary Bladder”
Ta-Chiang Liu, MD, PhD $1,015,114 from Helmsley Charitable Trust for “Cellular biomarkers for pediatric Crohn’s disease”
Steffen Storck, PhD $200,000 award from the Alzheimer's Association to study how the systems involved in controlling how fluid flows into, through and out of the brain interact with each other and affect the development of Alzheimer’s disease
Steven Van Dyken, PhD $4.1 million, 5-year grant from NIH for “Defining the role of IL-18 in atopic dermatitis”
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View more grants and awards in a new section of the website, "Grants and Notables."
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| Department of Pathology & Immunology Washington University School of Medicine
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