School of Medicine Basic Sciences departments

Biochemistry

• VARP binds SNX27 to promote endosomal supercomplexformation on membranes. Science Advances.
  Mintu Chandra*, Amy Kendall, Marijn Ford, Lauren Jackson*.
  
  College of Arts and Science: Jackson Lab reveals relationship between transport proteins and brain disease
  
  
• Helicobacter pylori CagA and Cag type IV secretion systemactivity have key roles in triggering gastric transcriptional andproteomic alterations. Infection and Immunity.
  Jennifer Shuman*, Aung Soe Lin, Mandy Westland, Kaeli Bryant, Gabrielle Fortier, M Blanca Piazuelo, Michelle Reyzer, Audra Judd, Tina Tsui, W. Hayes McDonald, Mark McClain, Kevin Schey, Holly Algood, Timothy Cover*.
  
  School of Medicine Basic Sciences: To cause cancer or not to cause cancer: What leads to H. pylori-induced stomach malignancies.
  
  
• A thiouracil desulfurase protects Clostridioides difficile RNA from 4-thiouracil incorporation, providing a competitive advantage in the gut. Cell Host & Microbe.
  Matthew Munneke, Catherine Shelton, Darian Carroll, Nicole Kirchoff, Martin Douglass, M. Wade Calcutt, Katherine Gibson-Corley, Maribeth Nicholson, Mariana Byndloss, Eric Skaar.
  
  VUMC News: C. diff uses toxic compound to fuel growth advantage
  
  Genetic Engineering & Biotechnology News: Toxic Compound Gives C. difficile Competitive Advantage in Infected Gut
  
  

Cell and Developmental Biology

• Mitochondrial and peroxisomal fission in cortical neurogenesis. The International Journal of Biochemistry & Cell Biology.
  Gabriella Robertson*, Caroline Bodnya, Vivian Gama*.
  
  
• Multiplexed cytometry for single cell chemical biology. Methods in Cell Biology.
  Henry Schares*, Madeline Hayes, Joseph Balsamo, Hannah Thirman, Brian Bachmann, Jonathan Irish*.
  
  
• The Genetic Architecture of Congenital Diarrhea and Enteropathy. New England Journal of Medicine.
  Zeenat Gaibee* (Hospital for Sick Children), Suli Mao, Sari Acra, Matthew Tyska, James Goldenring, Martín Martín* (University of California, Los Angeles), Jay Thiagarajah* (Boston Children’s Hospital and Harvard Medical School), Aleixo Muise* (Hospital for Sick Children, University of Toronto).
  
  
• Dipeptidase-1 knockout mice develop invasive tumors with features of microsatellite unstable colorectal cancer. JCI Insight.
  Sarah Glass*, Matthew Bechard, Zheng Cao, Radhika Aramandla, Ping Zhao, Samuel Ellis, Emily Green, Elizabeth Fisher, Ryan Smith, Chelsie Sievers, Maria Johnson Irudayam, Frank Revetta, M Kay Washington, Gregory Ayers, Cody Heiser, Alan Simmons, Yanwen Xu, Yu Wang, Martha Shrubsole, Nicholas Markham, Qi Liu, Ken Lau, Robert Coffey*.
  
  
• Tenascin-C potentiates Wnt signaling in thyroid cancer. Endocrinology.
  Heather Hartmann*, Matthew Loberg, George Xu, Anna Schwarzkopf, Sheau-Chiann Chen, Courtney Phifer, Kailey Caroland, Hua-Chang Chen, Diana Diaz, Megan Tigue, Amanda Hesterberg, Jean-Nicolas Gallant, Quanhu Sheng, James Netterville, Sarah Rohde, Carmen Solórzano, Lindsay Bischoff, Naira Baregamian, Paula Hurley, Barbara Murphy, Jennifer Choe, Fei Ye, Ethan Lee, Vivian Weiss*.
  
  School of Medicine Basic Sciences: Vanderbilt researchers identify key molecular driver in aggressive thyroid cancer

Pharmacology

• Total Synthesis and Pharmacological Evaluation of Phochrodines A-C. Journal of Natural Products.
  Jacob L Bouchard*, Sichen Chang, Srinivasan Krishnan, Christopher Presley, Olivier Boutaud, Nathan Schley, Darren Engers, Julie Engers, Craig Lindsley, Aaron Bender*.
  
  
• Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis. Frontiers in Pharmacology.
  Montana Young*, Ryan Ceddia, Analisa Thompson-Gray, David Reyes, Jackson Cassada, Julio Ayala, Owen McGuinness, Sheila Collins, Heidi Hamm.
  

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